Ferulic acid_COLO 205 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Ferulic acid perturbation in COLO 205 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Ferulic acid_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
BTBD9 BTB (POZ) domain containing 9 0.139482
NDRG1 N-myc downstream regulated 1 0.0771461
MBNL2 muscleblind-like splicing regulator 2 0.0770555
ZMYND8 zinc finger, MYND-type containing 8 0.0731879
UBR2 ubiquitin protein ligase E3 component n-recognin 2 0.0665855
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.0658467
ARHGAP26 Rho GTPase activating protein 26 0.0591932
PARP4 poly (ADP-ribose) polymerase family, member 4 0.0576093
MYH9 myosin, heavy chain 9, non-muscle 0.0569894
RNF43 ring finger protein 43 0.0565329
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 0.0550808
ZMYM2 zinc finger, MYM-type 2 0.0549659
PRELID2 PRELI domain containing 2 0.0545459
N4BP2L2 NEDD4 binding protein 2-like 2 0.0528494
RUNX1 runt-related transcription factor 1 0.0527206
FAT1 FAT atypical cadherin 1 0.052632
UBAC2 UBA domain containing 2 0.0525508
PAN3 PAN3 poly(A) specific ribonuclease subunit 0.0521727
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0515095
PHF3 PHD finger protein 3 0.0512213
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0494148
FNDC3A fibronectin type III domain containing 3A 0.0484712
EGLN3 egl-9 family hypoxia-inducible factor 3 0.0484299
IFNGR1 interferon gamma receptor 1 0.04794
TRIO trio Rho guanine nucleotide exchange factor 0.0453986
MLPH melanophilin 0.0450327
RNF149 ring finger protein 149 0.0450102
DSCAM Down syndrome cell adhesion molecule 0.0447296
SORBS1 sorbin and SH3 domain containing 1 0.0447276
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 0.043777
ARGLU1 arginine and glutamate rich 1 0.0437426
AHI1 Abelson helper integration site 1 0.0435483
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 0.0434982
MCTP2 multiple C2 domains, transmembrane 2 0.0429078
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 0.0421492
SREBF2 sterol regulatory element binding transcription factor 2 0.041764
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 0.0414366
AFF1 AF4/FMR2 family, member 1 0.0407815
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0401687
NRIP1 nuclear receptor interacting protein 1 0.0399164
FNDC3B fibronectin type III domain containing 3B 0.0398414
ATXN1 ataxin 1 0.0397143
PTBP3 polypyrimidine tract binding protein 3 0.0393745
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0393217
TXNIP thioredoxin interacting protein 0.0377104
SMAD3 SMAD family member 3 0.0374431
RAD51B RAD51 paralog B 0.0373355
NCKAP5 NCK-associated protein 5 0.0370742
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.0366512
BHLHE40 basic helix-loop-helix family, member e40 0.0361548
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 0.0359891
MSI2 musashi RNA-binding protein 2 0.0352393
PTEN phosphatase and tensin homolog 0.0352038
ARHGAP32 Rho GTPase activating protein 32 0.0351969
FHIP1A FHF complex subunit HOOK interacting protein 1A 0.0351832
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.034684
SBF2 SET binding factor 2 0.0341205
ABHD2 abhydrolase domain containing 2 0.0338664
PHC3 polyhomeotic homolog 3 (Drosophila) 0.033747
AOPEP aminopeptidase O (putative) 0.0333812
HDAC4 histone deacetylase 4 0.0332232
TM9SF2 transmembrane 9 superfamily member 2 0.0331814
RBM26 RNA binding motif protein 26 0.0331089
VEGFA vascular endothelial growth factor A 0.0322865
GRK3 G protein-coupled receptor kinase 3 0.0321538
RHOBTB3 Rho-related BTB domain containing 3 0.0321384
FNIP1 folliculin interacting protein 1 0.0317729
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like 0.0313537
OARD1 O-acyl-ADP-ribose deacylase 1 0.0307249
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0306528
ERRFI1 ERBB receptor feedback inhibitor 1 0.0305901
PDK3 pyruvate dehydrogenase kinase, isozyme 3 0.0305045
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.0304164
PTK2 protein tyrosine kinase 2 0.0300417
ZNF148 zinc finger protein 148 0.029984
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.0297754
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.0294938
PATJ PATJ crumbs cell polarity complex component 0.0294207
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0290994
NCOR1 nuclear receptor corepressor 1 0.0289868
TTC3 tetratricopeptide repeat domain 3 0.0288408
MYO10 myosin X 0.0287691
ESYT2 extended synaptotagmin-like protein 2 0.0285244
ZBTB20 zinc finger and BTB domain containing 20 0.0284412
COPA coatomer protein complex, subunit alpha 0.0282762
SPATA13 spermatogenesis associated 13 0.0281292
BICRAL BICRA like chromatin remodeling complex associated protein 0.0281085
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.0280156
CANX calnexin 0.0279003
ASPH aspartate beta-hydroxylase 0.0277461
H1-0 H1.0 linker histone 0.0275476
ATP11A ATPase, class VI, type 11A 0.0273823
LPP LIM domain containing preferred translocation partner in lipoma 0.0272024
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0271895
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.0269268
KIF16B kinesin family member 16B 0.0269233
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0265312
SAMD12 sterile alpha motif domain containing 12 0.0264313
ZDHHC20 zinc finger, DHHC-type containing 20 0.0260974
TBC1D22A TBC1 domain family, member 22A 0.0259854

decreased expression

Symbol Name Standardized Value
EGR1 early growth response 1 -0.119144
LMO7 LIM domain 7 -0.114374
INTS6 integrator complex subunit 6 -0.10602
ANXA2 annexin A2 -0.0887411
TPT1 tumor protein, translationally-controlled 1 -0.0828336
AREG amphiregulin -0.0707512
SQSTM1 sequestosome 1 -0.0685228
RAB7A RAB7A, member RAS oncogene family -0.0647716
B2M beta-2-microglobulin -0.0618004
LOC102724023 ES1 protein homolog, mitochondrial -0.0579847
EZR ezrin -0.057459
RIGI RNA sensor RIG-I -0.0566751
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 -0.0561896
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0559793
PERP PERP, TP53 apoptosis effector -0.0556318
FOS FBJ murine osteosarcoma viral oncogene homolog -0.0555568
SP100 SP100 nuclear antigen -0.0547282
IFI6 interferon, alpha-inducible protein 6 -0.0536624
PTMA prothymosin, alpha -0.0519714
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0478077
MYO1E myosin IE -0.0475938
VCL vinculin -0.0453336
MX2 MX dynamin-like GTPase 2 -0.0445274
LCN2 lipocalin 2 -0.0430484
JUN jun proto-oncogene -0.0425486
FTL ferritin, light polypeptide -0.0419757
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0409553
ERN1 endoplasmic reticulum to nucleus signaling 1 -0.0399575
TJP1 tight junction protein 1 -0.0398353
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -0.0392543
RNF213 ring finger protein 213 -0.0381492
HLA-B major histocompatibility complex, class I, B -0.0380018
PLSCR2 phospholipid scramblase 2 -0.0373125
RSAD2 radical S-adenosyl methionine domain containing 2 -0.0361411
C6ORF132 chromosome 6 open reading frame 132 -0.0356307
ACTG1 actin gamma 1 -0.0353663
IRF1 interferon regulatory factor 1 -0.0353567
IFI27 interferon, alpha-inducible protein 27 -0.0352157
TMSB10 thymosin beta 10 -0.0347384
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 -0.0346497
PLSCR1 phospholipid scramblase 1 -0.0343568
EFNB2 ephrin-B2 -0.0339461
MCL1 myeloid cell leukemia 1 -0.0336445
RPL35A ribosomal protein L35a -0.0327499
NABP1 nucleic acid binding protein 1 -0.032512
MT2A metallothionein 2A -0.0308704
MCTP1 multiple C2 domains, transmembrane 1 -0.0302654
MX1 MX dynamin-like GTPase 1 -0.0299177
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.0289595
CATSPERB catsper channel auxiliary subunit beta -0.0288241
XAF1 XIAP associated factor 1 -0.0284211
BLZF1 basic leucine zipper nuclear factor 1 -0.0277944
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.0276449
DDIT3 DNA-damage-inducible transcript 3 -0.0276406
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0275047
BAIAP2L1 BAI1-associated protein 2-like 1 -0.0270781
PHACTR4 phosphatase and actin regulator 4 -0.0269072
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0265898
UBAP2 ubiquitin associated protein 2 -0.0264208
TMC5 transmembrane channel-like 5 -0.0264146
NPSR1 neuropeptide S receptor 1 -0.0264013
S100A10 S100 calcium binding protein A10 -0.0253199
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.0249054
CYSTM1 cysteine-rich transmembrane module containing 1 -0.0248373
S100A6 S100 calcium binding protein A6 -0.0247972
LYZ lysozyme -0.024766
TM4SF19 transmembrane 4 L six family member 19 -0.0244721
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0244511
RPL23 ribosomal protein L23 -0.0243583
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0241782
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.0238108
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0235636
ITPKC inositol-trisphosphate 3-kinase C -0.023393
STS steroid sulfatase (microsomal), isozyme S -0.0231572
RPLP1 ribosomal protein, large, P1 -0.0230489
GCLC glutamate-cysteine ligase, catalytic subunit -0.0229691
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.0229584
SLC38A2 solute carrier family 38, member 2 -0.0226926
FBXO39 F-box protein 39 -0.0225816
RPS6 ribosomal protein S6 -0.0224087
IER2 immediate early response 2 -0.0222514
FTH1 ferritin, heavy polypeptide 1 -0.0218639
IER3 immediate early response 3 -0.0216781
FOSL1 FOS-like antigen 1 -0.0216515
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.021491
HLA-E major histocompatibility complex, class I, E -0.0213239
ERBIN erbb2 interacting protein -0.0211716
HLA-A major histocompatibility complex, class I, A -0.020995
IFITM3 interferon induced transmembrane protein 3 -0.0209559
TM4SF1 transmembrane 4 L six family member 1 -0.0208189
RPL31 ribosomal protein L31 -0.0206803
TSHZ2 teashirt zinc finger homeobox 2 -0.0205511
CLDN4 claudin 4 -0.0205388
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 -0.0203133
SLC38A1 solute carrier family 38, member 1 -0.0201957
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.0201477
GMDS GDP-mannose 4,6-dehydratase -0.0198969
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.0197564
POF1B premature ovarian failure, 1B -0.0197562
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.0196041