Ferulic acid_HOP62 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Ferulic acid perturbation in HOP62 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Ferulic acid_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
TRIO trio Rho guanine nucleotide exchange factor 0.118249
NDRG1 N-myc downstream regulated 1 0.117157
FNDC3B fibronectin type III domain containing 3B 0.112772
ELL2 elongation factor, RNA polymerase II, 2 0.102848
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0739854
PLEC plectin 0.0720294
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0672513
MYH9 myosin, heavy chain 9, non-muscle 0.0630967
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0624827
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0587544
FAM13A family with sequence similarity 13, member A 0.0558799
SEPTIN9 septin 9 0.0551306
NAV2 neuron navigator 2 0.054662
FLNB filamin B, beta 0.0509737
VEGFA vascular endothelial growth factor A 0.0481153
ANKRD11 ankyrin repeat domain 11 0.0480428
SMAD3 SMAD family member 3 0.0475969
HPCAL1 hippocalcin-like 1 0.0461344
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0419834
SIPA1L3 signal-induced proliferation-associated 1 like 3 0.0403718
PTPRM protein tyrosine phosphatase, receptor type, M 0.0393184
ZNF292 zinc finger protein 292 0.038482
MSN moesin 0.0379845
PPARD peroxisome proliferator-activated receptor delta 0.0366069
RRM2 ribonucleotide reductase M2 0.0359469
NUP58 nucleoporin 58 0.0358524
SHB Src homology 2 domain containing adaptor protein B 0.03542
COL6A3 collagen, type VI, alpha 3 0.0349805
FLNA filamin A, alpha 0.0343753
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0338336
EEF2 eukaryotic translation elongation factor 2 0.0336381
PTK2 protein tyrosine kinase 2 0.0335098
USP3 ubiquitin specific peptidase 3 0.0324487
BHLHE40 basic helix-loop-helix family, member e40 0.0312472
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0309966
NAMPT nicotinamide phosphoribosyltransferase 0.0308653
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0303226
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0300819
PKM pyruvate kinase, muscle 0.0298522
ERRFI1 ERBB receptor feedback inhibitor 1 0.0296738
ATP13A3 ATPase type 13A3 0.0289629
CD44 CD44 molecule (Indian blood group) 0.0286891
ACTN4 actinin, alpha 4 0.0284662
TFG TRK-fused gene 0.0282374
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0279257
TAC4 tachykinin 4 (hemokinin) 0.0272076
JARID2 jumonji, AT rich interactive domain 2 0.0267084
RNF145 ring finger protein 145 0.0263135
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0256349
HELZ helicase with zinc finger 0.0255506
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0254034
TNIP1 TNFAIP3 interacting protein 1 0.0250197
RYBP RING1 and YY1 binding protein 0.0247949
RUNX1 runt-related transcription factor 1 0.0243932
TNS1 tensin 1 0.0242781
KMT2E lysine (K)-specific methyltransferase 2E 0.0240664
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0238912
HSPA8 heat shock 70kDa protein 8 0.0237993
SPAG9 sperm associated antigen 9 0.0237504
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0236154
UBA6 ubiquitin-like modifier activating enzyme 6 0.0235272
MAP3K2 mitogen-activated protein kinase kinase kinase 2 0.0234862
CDCP1 CUB domain containing protein 1 0.0231253
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.0227336
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0225536
SFPQ splicing factor proline/glutamine-rich 0.0221911
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0219596
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0218069
RTN4 reticulon 4 0.0215349
WDR45B WD repeat domain 45B 0.0212521
IQGAP3 IQ motif containing GTPase activating protein 3 0.0212271
TFRC transferrin receptor 0.0209816
NPTN neuroplastin 0.0209633
AXL AXL receptor tyrosine kinase 0.0208883
FOSL1 FOS-like antigen 1 0.0208654
MPRIP myosin phosphatase Rho interacting protein 0.0208588
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 0.0207462
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0206648
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0206049
ADAM17 ADAM metallopeptidase domain 17 0.0203705
RPL3 ribosomal protein L3 0.020205
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0198964
TOP2B topoisomerase (DNA) II beta 180kDa 0.0198225
DTNA dystrobrevin, alpha 0.0198187
TUBB6 tubulin, beta 6 class V 0.0197239
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 0.0196597
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.019507
TPM3 tropomyosin 3 0.019371
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.0193159
RCOR1 REST corepressor 1 0.0192863
ARRDC3 arrestin domain containing 3 0.0190258
SYAP1 synapse associated protein 1 0.0190208
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0189799
CCNL1 cyclin L1 0.0187468
UGCG UDP-glucose ceramide glucosyltransferase 0.0186111
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.0184271
WAC WW domain containing adaptor with coiled-coil 0.0183568
NR1D2 nuclear receptor subfamily 1, group D, member 2 0.0183396
PCBP2 poly(rC) binding protein 2 0.0183137
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0182952

decreased expression

Symbol Name Standardized Value
FN1 fibronectin 1 -0.255244
VIM vimentin -0.2096
HMGA2 high mobility group AT-hook 2 -0.130222
CDH13 cadherin 13 -0.0893297
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0761008
RAI14 retinoic acid induced 14 -0.0737745
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.073621
TMSB10 thymosin beta 10 -0.0707773
LOX lysyl oxidase -0.0694424
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0651209
IGF2 insulin-like growth factor 2 -0.0533429
AHNAK AHNAK nucleoprotein -0.0478301
FMN1 formin 1 -0.0453352
CCND1 cyclin D1 -0.045088
DST dystonin -0.0418809
ACTG1 actin gamma 1 -0.0414879
CANX calnexin -0.0406932
TENM2 teneurin transmembrane protein 2 -0.039865
LAMB3 laminin, beta 3 -0.0368389
ASPH aspartate beta-hydroxylase -0.0360923
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric -0.0328047
CLMP CXADR-like membrane protein -0.0327752
COL1A1 collagen, type I, alpha 1 -0.031469
EXT1 exostosin glycosyltransferase 1 -0.0314422
MAML3 mastermind-like 3 (Drosophila) -0.0299893
INHBA inhibin, beta A -0.028777
RRBP1 ribosome binding protein 1 -0.0280539
GLIS3 GLIS family zinc finger 3 -0.0278033
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 -0.0276122
NF1 neurofibromin 1 -0.0271852
ZMYND8 zinc finger, MYND-type containing 8 -0.0271038
TAS2R14 taste receptor, type 2, member 14 -0.0268397
CAVIN1 caveolae associated protein 1 -0.0265598
IL1B interleukin 1, beta -0.0263564
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.026072
ADARB1 adenosine deaminase, RNA-specific, B1 -0.0247512
TTC3 tetratricopeptide repeat domain 3 -0.0245087
ZBTB20 zinc finger and BTB domain containing 20 -0.0242829
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.02416
MYO9A myosin IXA -0.0239248
MBD5 methyl-CpG binding domain protein 5 -0.0234394
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -0.0233302
TAOK1 TAO kinase 1 -0.0227758
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0227272
EIF1 eukaryotic translation initiation factor 1 -0.022567
ERC1 ELKS/RAB6-interacting/CAST family member 1 -0.0224898
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 -0.0220792
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.021828
RIN2 Ras and Rab interactor 2 -0.0217062
ANKIB1 ankyrin repeat and IBR domain containing 1 -0.0213438
BASP1 brain abundant, membrane attached signal protein 1 -0.0209178
GOLGB1 golgin B1 -0.020499
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0204314
IGFBP3 insulin-like growth factor binding protein 3 -0.0203991
FBXL2 F-box and leucine-rich repeat protein 2 -0.0200502
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0199961
NABP1 nucleic acid binding protein 1 -0.0197861
BTG1 B-cell translocation gene 1, anti-proliferative -0.0196763
EGFR epidermal growth factor receptor -0.0195852
CHD9 chromodomain helicase DNA binding protein 9 -0.0195736
LIMCH1 LIM and calponin homology domains 1 -0.0191464
HDLBP high density lipoprotein binding protein -0.0191393
SAMD3 sterile alpha motif domain containing 3 -0.019062
PTMA prothymosin, alpha -0.0189206
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0187618
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0186274
EHBP1 EH domain binding protein 1 -0.0186192
IGFBP4 insulin-like growth factor binding protein 4 -0.0186088
COL5A1 collagen, type V, alpha 1 -0.0185682
TNNC1 troponin C type 1 (slow) -0.0185283
APOLD1 apolipoprotein L domain containing 1 -0.0183785
DNAAF9 dynein axonemal assembly factor 9 -0.0178325
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -0.0177289
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 -0.0176953
NALF1 NALCN channel auxiliary factor 1 -0.0175984
BPTF bromodomain PHD finger transcription factor -0.0172526
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -0.0171987
OSMR oncostatin M receptor -0.0171072
BBS9 Bardet-Biedl syndrome 9 -0.0167473
AFF3 AF4/FMR2 family, member 3 -0.0165919
ENO1 enolase 1, (alpha) -0.0165156
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0163153
ATRX alpha thalassemia/mental retardation syndrome X-linked -0.0160839
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0159662
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.0158921
TRPS1 trichorhinophalangeal syndrome I -0.015626
PCNX4 pecanex 4 -0.0156175
SOX5 SRY (sex determining region Y)-box 5 -0.0155912
KLF12 Kruppel-like factor 12 -0.0155762
SAMD4A sterile alpha motif domain containing 4A -0.0155437
ARHGAP22 Rho GTPase activating protein 22 -0.0154195
ANKHD1 ankyrin repeat and KH domain containing 1 -0.0153517
COL6A1 collagen, type VI, alpha 1 -0.0149779
ZNF804A zinc finger protein 804A -0.0148411
ANTXR2 anthrax toxin receptor 2 -0.0146979
FRMD4A FERM domain containing 4A -0.0146543
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0145268
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0142709
S100A6 S100 calcium binding protein A6 -0.0139927
ANKRD28 ankyrin repeat domain 28 -0.0136988