Ferulic acid_HS-578T Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Ferulic acid perturbation in HS-578T cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Ferulic acid_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
COL6A3 collagen, type VI, alpha 3 0.487072
FN1 fibronectin 1 0.342924
NDRG1 N-myc downstream regulated 1 0.216785
MYH9 myosin, heavy chain 9, non-muscle 0.182774
IGFBP3 insulin-like growth factor binding protein 3 0.157846
VEGFA vascular endothelial growth factor A 0.132629
PLEC plectin 0.112266
PABPC1 poly(A) binding protein, cytoplasmic 1 0.105067
CADM1 cell adhesion molecule 1 0.103233
EEF2 eukaryotic translation elongation factor 2 0.0953094
TRIO trio Rho guanine nucleotide exchange factor 0.0932618
BHLHE40 basic helix-loop-helix family, member e40 0.0728737
COL5A1 collagen, type V, alpha 1 0.071583
TPM4 tropomyosin 4 0.0622806
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.058968
FLNA filamin A, alpha 0.0574869
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.0515243
CALR calreticulin 0.0508112
CDH13 cadherin 13 0.0495933
ANKRD11 ankyrin repeat domain 11 0.0493655
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.0454324
EGR1 early growth response 1 0.044202
MACF1 microtubule-actin crosslinking factor 1 0.0417608
APP amyloid beta (A4) precursor protein 0.0397611
ATP13A3 ATPase type 13A3 0.0387686
TNIP1 TNFAIP3 interacting protein 1 0.0386812
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.0379969
CAMTA1 calmodulin binding transcription activator 1 0.0374782
COL7A1 collagen, type VII, alpha 1 0.0374399
ZFAND3 zinc finger, AN1-type domain 3 0.0369383
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0351734
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.0349579
MRTFA myocardin related transcription factor A 0.0337542
RBMS3 RNA binding motif, single stranded interacting protein 3 0.0336681
ADAM17 ADAM metallopeptidase domain 17 0.0334561
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.0333828
GRB10 growth factor receptor-bound protein 10 0.0322881
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0320934
TFG TRK-fused gene 0.0319717
ANXA2 annexin A2 0.0316676
MED15 mediator complex subunit 15 0.0311997
LPP LIM domain containing preferred translocation partner in lipoma 0.0308052
TMSB10 thymosin beta 10 0.0303583
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.0298776
GSK3B glycogen synthase kinase 3 beta 0.0298219
RIGI RNA sensor RIG-I 0.0291636
TMED9 transmembrane emp24 protein transport domain containing 9 0.0288323
ACTN4 actinin, alpha 4 0.0288094
ANXA5 annexin A5 0.0282188
STC2 stanniocalcin 2 0.0277903
GARS1 glycyl-tRNA synthetase 1 0.0274565
CLIC4 chloride intracellular channel 4 0.0272721
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.0272347
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0271018
NAV2 neuron navigator 2 0.0270065
TIMP3 TIMP metallopeptidase inhibitor 3 0.0269432
MAP2K1 mitogen-activated protein kinase kinase 1 0.0266722
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0265943
LOC112694756 uncharaterized LOC112694756 0.0265913
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 0.0263577
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.0260081
NCOR2 nuclear receptor corepressor 2 0.0258039
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0257791
LUC7L2 LUC7-like 2 (S. cerevisiae) 0.0257014
ACTN1 actinin, alpha 1 0.0256209
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 0.0252837
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0249912
AHDC1 AT hook, DNA binding motif, containing 1 0.0249785
DDIT4 DNA-damage-inducible transcript 4 0.0249377
LOXL2 lysyl oxidase-like 2 0.0239567
EHD2 EH-domain containing 2 0.0237651
LENG8 leukocyte receptor cluster (LRC) member 8 0.0237322
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.0237198
GFPT1 glutamine--fructose-6-phosphate transaminase 1 0.023658
SEC31A SEC31 homolog A (S. cerevisiae) 0.0236164
YBX1 Y box binding protein 1 0.0235633
EXT1 exostosin glycosyltransferase 1 0.0235475
COG5 component of oligomeric golgi complex 5 0.023445
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0230981
CSNK1A1 casein kinase 1, alpha 1 0.0227678
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0225665
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.0224235
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0223807
FOXJ3 forkhead box J3 0.0222786
RAD23B RAD23 homolog B (S. cerevisiae) 0.022239
SPAG9 sperm associated antigen 9 0.0221918
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.0220536
JUN jun proto-oncogene 0.0219706
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 0.0219281
PARD3 par-3 family cell polarity regulator 0.0219167
PTPRF protein tyrosine phosphatase, receptor type, F 0.0218139
PDIA3 protein disulfide isomerase family A, member 3 0.0217351
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 0.0216432
PTPRJ protein tyrosine phosphatase, receptor type, J 0.0215445
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.0214403
TRAM2 translocation associated membrane protein 2 0.0211194
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0210313
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 0.020987
RHEB Ras homolog enriched in brain 0.0208431
NT5DC3 5'-nucleotidase domain containing 3 0.0206227

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.132514
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0982337
VIM vimentin -0.0863185
NKAIN3 Na+/K+ transporting ATPase interacting 3 -0.0821739
HMGA2 high mobility group AT-hook 2 -0.0762295
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.0756892
CD44 CD44 molecule (Indian blood group) -0.0730508
MT2A metallothionein 2A -0.0724348
WWTR1 WW domain containing transcription regulator 1 -0.0525616
ZBTB20 zinc finger and BTB domain containing 20 -0.0512042
PSD3 pleckstrin and Sec7 domain containing 3 -0.0501852
LDHA lactate dehydrogenase A -0.0428739
STC1 stanniocalcin 1 -0.0411962
RPS2 ribosomal protein S2 -0.0381804
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0359621
ASPH aspartate beta-hydroxylase -0.0354895
COL1A2 collagen, type I, alpha 2 -0.0352574
IGFBP7 insulin-like growth factor binding protein 7 -0.0348485
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0329602
GLIS3 GLIS family zinc finger 3 -0.0321154
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -0.0309091
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0304189
ERRFI1 ERBB receptor feedback inhibitor 1 -0.0297855
TMF1 TATA element modulatory factor 1 -0.0274967
AHNAK AHNAK nucleoprotein -0.0274353
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) -0.0256636
HAS2 hyaluronan synthase 2 -0.0255596
LIMS1 LIM and senescent cell antigen-like domains 1 -0.024684
LTBP1 latent transforming growth factor beta binding protein 1 -0.023003
GOLGB1 golgin B1 -0.022849
IER3 immediate early response 3 -0.0223688
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0214813
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 -0.021448
TPT1 tumor protein, translationally-controlled 1 -0.021353
TRPS1 trichorhinophalangeal syndrome I -0.0213004
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0212678
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.021155
GFPT2 glutamine-fructose-6-phosphate transaminase 2 -0.0210652
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1 -0.0210114
ALCAM activated leukocyte cell adhesion molecule -0.0199857
ZBTB38 zinc finger and BTB domain containing 38 -0.0199501
RPL7 ribosomal protein L7 -0.0198055
ECE1 endothelin converting enzyme 1 -0.0193055
IL6ST interleukin 6 signal transducer -0.0187552
MAP1B microtubule-associated protein 1B -0.0186281
FTL ferritin, light polypeptide -0.0185739
MT1X metallothionein 1X -0.0182176
UBC ubiquitin C -0.0178843
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0176846
ABI3BP ABI family, member 3 (NESH) binding protein -0.017459
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0172183
MBD5 methyl-CpG binding domain protein 5 -0.0171302
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0166597
SAMD9 sterile alpha motif domain containing 9 -0.0165611
COL3A1 collagen, type III, alpha 1 -0.0165411
SIPA1L1 signal-induced proliferation-associated 1 like 1 -0.0164056
NF1 neurofibromin 1 -0.0162659
DUSP6 dual specificity phosphatase 6 -0.0162652
SQSTM1 sequestosome 1 -0.0161782
OXR1 oxidation resistance 1 -0.0161655
VMP1 vacuole membrane protein 1 -0.0160397
PDE4D phosphodiesterase 4D, cAMP-specific -0.0158026
AGO3 argonaute RISC catalytic component 3 -0.0156112
BIRC2 baculoviral IAP repeat containing 2 -0.0156041
SKAP2 src kinase associated phosphoprotein 2 -0.0153417
SPIDR scaffolding protein involved in DNA repair -0.0151228
STK38L serine/threonine kinase 38 like -0.014911
DPYSL3 dihydropyrimidinase-like 3 -0.0147995
TRPC1 transient receptor potential cation channel, subfamily C, member 1 -0.0147397
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.0145581
ANTXR2 anthrax toxin receptor 2 -0.014551
MX2 MX dynamin-like GTPase 2 -0.0145108
IFI16 interferon, gamma-inducible protein 16 -0.014469
FAM114A1 family with sequence similarity 114, member A1 -0.0144455
OSMR oncostatin M receptor -0.0143358
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.014262
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.013885
CLU clusterin -0.0137893
TGFBI transforming growth factor, beta-induced, 68kDa -0.013704
RAI14 retinoic acid induced 14 -0.0136156
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha -0.0135413
H1-4 H1.4 linker histone, cluster member -0.0134128
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0133944
NRP1 neuropilin 1 -0.0132621
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.0132466
ARHGAP22 Rho GTPase activating protein 22 -0.0130771
FAM107B family with sequence similarity 107, member B -0.0130324
AHR aryl hydrocarbon receptor -0.0128534
XPO1 exportin 1 -0.0127575
CENPF centromere protein F, 350/400kDa -0.0126934
LEPROT leptin receptor overlapping transcript -0.0126302
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.0126151
RBM25 RNA binding motif protein 25 -0.0125988
BBS9 Bardet-Biedl syndrome 9 -0.0125643
ANGPTL4 angiopoietin-like 4 -0.012473
KIF2A kinesin heavy chain member 2A -0.0124639
DST dystonin -0.0123557
DSTN destrin (actin depolymerizing factor) -0.0121596
UBAP2 ubiquitin associated protein 2 -0.0120939
SNX14 sorting nexin 14 -0.01201