| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ferulic acid perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ferulic acid_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.269743 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.253189 |
| FNDC3B | fibronectin type III domain containing 3B | 0.183453 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.150631 |
| VEGFA | vascular endothelial growth factor A | 0.126981 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.11466 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.114336 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.114111 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.109528 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0959614 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0952268 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0912158 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.08613 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0843594 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.081529 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0795466 |
| PEG3 | paternally expressed 3 | 0.0747915 |
| AFDN | afadin, adherens junction formation factor | 0.0747895 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0731195 |
| PLEC | plectin | 0.0691844 |
| FAT1 | FAT atypical cadherin 1 | 0.0670408 |
| IGF2 | insulin-like growth factor 2 | 0.0661377 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0660645 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0653085 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0644913 |
| NPAS2 | neuronal PAS domain protein 2 | 0.063934 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0635224 |
| CFB | complement factor B | 0.0631485 |
| C3 | complement component 3 | 0.0619732 |
| APOA2 | apolipoprotein A-II | 0.0612292 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0592091 |
| KRT8 | keratin 8, type II | 0.0587095 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0585654 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0583296 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0581145 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0561421 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0555587 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0536148 |
| ATXN1 | ataxin 1 | 0.0530898 |
| FLNB | filamin B, beta | 0.052989 |
| A2M | alpha-2-macroglobulin | 0.0529761 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.0527699 |
| IQSEC1 | IQ motif and Sec7 domain 1 | 0.05274 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0510372 |
| TNS1 | tensin 1 | 0.0495459 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0482657 |
| DST | dystonin | 0.0475532 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0475319 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0474036 |
| ENO1 | enolase 1, (alpha) | 0.0472824 |
| DSPP | dentin sialophosphoprotein | 0.0458437 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0452457 |
| EGR1 | early growth response 1 | 0.0450928 |
| APOB | apolipoprotein B | 0.0450879 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0447314 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.044694 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0444369 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0444309 |
| RACK1 | receptor for activated C kinase 1 | 0.0441296 |
| RPL23 | ribosomal protein L23 | 0.0441013 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0439248 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0431201 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0429854 |
| MSI2 | musashi RNA-binding protein 2 | 0.0426087 |
| KRT18 | keratin 18, type I | 0.0425785 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0424442 |
| APOA1 | apolipoprotein A-I | 0.0408092 |
| FMNL2 | formin-like 2 | 0.0407341 |
| NDRG1 | N-myc downstream regulated 1 | 0.0403976 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0392221 |
| PRRC2B | proline-rich coiled-coil 2B | 0.038837 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0386576 |
| RPL3 | ribosomal protein L3 | 0.0383641 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0379903 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0378878 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0376561 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0371776 |
| RNF213 | ring finger protein 213 | 0.0366108 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0365428 |
| MT2A | metallothionein 2A | 0.0362969 |
| KIAA1217 | KIAA1217 | 0.0358116 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0356475 |
| PARD3 | par-3 family cell polarity regulator | 0.0353879 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0350865 |
| APOE | apolipoprotein E | 0.033964 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0329378 |
| EHBP1 | EH domain binding protein 1 | 0.0318464 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0317283 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0316652 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0315946 |
| RPLP0 | ribosomal protein, large, P0 | 0.0311743 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0311171 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.031009 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0310016 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0309742 |
| FLNA | filamin A, alpha | 0.0308325 |
| ARFGEF3 | ARFGEF family member 3 | 0.030768 |
| RASGRF2 | Ras protein-specific guanine nucleotide-releasing factor 2 | 0.0306925 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0302399 |
| H1-0 | H1.0 linker histone | 0.0302285 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.197697 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0553801 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0510261 |
| RPS2 | ribosomal protein S2 | -0.0446333 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0386528 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0378736 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0302094 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0272473 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0265096 |
| PAPOLA | poly(A) polymerase alpha | -0.0262463 |
| GPC6 | glypican 6 | -0.0261896 |
| UBXN4 | UBX domain protein 4 | -0.0256801 |
| JMJD1C | jumonji domain containing 1C | -0.0246409 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.0243463 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0242681 |
| RPL21 | ribosomal protein L21 | -0.0240018 |
| RPS24 | ribosomal protein S24 | -0.0237005 |
| RPS6 | ribosomal protein S6 | -0.0235651 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0232497 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0230932 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.022002 |
| GOLGB1 | golgin B1 | -0.0216657 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | -0.0216639 |
| RBM25 | RNA binding motif protein 25 | -0.0214625 |
| DSTN | destrin (actin depolymerizing factor) | -0.0213539 |
| GPC3 | glypican 3 | -0.020521 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0204568 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0204459 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0203749 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0198618 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0195844 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0195771 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0192441 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.019222 |
| IFNGR1 | interferon gamma receptor 1 | -0.018712 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0186525 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0186028 |
| GOLGA4 | golgin A4 | -0.0184337 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0184081 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0180251 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0177801 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0177149 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0176938 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0175981 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0173333 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0171269 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0170662 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0169243 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0164841 |
| CSNK1G3 | casein kinase 1, gamma 3 | -0.0162042 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.016119 |
| EXOC6B | exocyst complex component 6B | -0.0159668 |
| ATM | ATM serine/threonine kinase | -0.0156709 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | -0.0156282 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0155332 |
| LMO7 | LIM domain 7 | -0.0154357 |
| CLTC | clathrin, heavy chain (Hc) | -0.0154054 |
| VMP1 | vacuole membrane protein 1 | -0.0153848 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0153089 |
| RPL4 | ribosomal protein L4 | -0.015289 |
| SVIL | supervillin | -0.0151314 |
| TXNRD1 | thioredoxin reductase 1 | -0.0147486 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.0147275 |
| TMF1 | TATA element modulatory factor 1 | -0.01463 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0137743 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0137331 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0137279 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0137199 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0137014 |
| ZFR | zinc finger RNA binding protein | -0.0136389 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0135813 |
| PDS5A | PDS5 cohesin associated factor A | -0.0133507 |
| MCFD2 | multiple coagulation factor deficiency 2 | -0.0133316 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0132667 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0132101 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0131347 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0130652 |
| GPHN | gephyrin | -0.0130222 |
| HSPE1 | heat shock 10kDa protein 1 | -0.0130018 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0128831 |
| PRPF4B | pre-mRNA processing factor 4B | -0.0128522 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0128357 |
| RPS16 | ribosomal protein S16 | -0.012813 |
| RAB10 | RAB10, member RAS oncogene family | -0.012794 |
| DSG2 | desmoglein 2 | -0.0127689 |
| PERP | PERP, TP53 apoptosis effector | -0.0127341 |
| CD2AP | CD2-associated protein | -0.012665 |
| PCBP2 | poly(rC) binding protein 2 | -0.012664 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0126573 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0126002 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0124687 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0124213 |
| RASA2 | RAS p21 protein activator 2 | -0.0123453 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0123341 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0121908 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0120436 |
| HMGA1 | high mobility group AT-hook 1 | -0.0120416 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0120289 |
| H1-4 | H1.4 linker histone, cluster member | -0.0120273 |
| CCDC88A | coiled-coil domain containing 88A | -0.0119459 |
