Ferulic acid_Hs 766T Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Ferulic acid perturbation in Hs 766T cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Ferulic acid_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
FLNB filamin B, beta 0.211468
PLEC plectin 0.149696
NDRG1 N-myc downstream regulated 1 0.124558
TRIO trio Rho guanine nucleotide exchange factor 0.116095
MYH9 myosin, heavy chain 9, non-muscle 0.0920731
PODXL podocalyxin-like 0.0813081
MEF2A myocyte enhancer factor 2A 0.0797073
CEMIP cell migration inducing protein, hyaluronan binding 0.0731751
KRT6A keratin 6A, type II 0.0704043
PRELID2 PRELI domain containing 2 0.0693043
CUL4B cullin 4B 0.0675651
BHLHE40 basic helix-loop-helix family, member e40 0.0650189
SMAD3 SMAD family member 3 0.0629139
MSN moesin 0.0596695
FLNA filamin A, alpha 0.0594126
TGM2 transglutaminase 2 0.0584587
KIAA1217 KIAA1217 0.0577906
GRB10 growth factor receptor-bound protein 10 0.0573255
MTSS1 metastasis suppressor 1 0.0543844
NCOR2 nuclear receptor corepressor 2 0.0533829
ESYT2 extended synaptotagmin-like protein 2 0.0533088
HSPG2 heparan sulfate proteoglycan 2 0.0530977
NAV2 neuron navigator 2 0.0520759
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.0480858
MYOF myoferlin 0.047757
MACF1 microtubule-actin crosslinking factor 1 0.0453504
EFHD2 EF-hand domain family, member D2 0.044976
BLCAP bladder cancer associated protein 0.0445146
LOC112694756 uncharaterized LOC112694756 0.0438025
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.043718
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 0.0436105
RAI14 retinoic acid induced 14 0.0431924
CEP250 centrosomal protein 250kDa 0.0426412
ATXN1 ataxin 1 0.0423226
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 0.040637
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.0404662
ANLN anillin, actin binding protein 0.0402282
EEF2 eukaryotic translation elongation factor 2 0.0400925
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0391826
CD44 CD44 molecule (Indian blood group) 0.0389776
MEGF6 multiple EGF-like-domains 6 0.0388619
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.0376146
EHBP1L1 EH domain binding protein 1-like 1 0.0376013
PDK3 pyruvate dehydrogenase kinase, isozyme 3 0.0370406
RICTOR RPTOR independent companion of MTOR, complex 2 0.0369016
ARRDC3 arrestin domain containing 3 0.0367349
APLP2 amyloid beta (A4) precursor-like protein 2 0.0366407
TNIP1 TNFAIP3 interacting protein 1 0.0363649
LMNA lamin A/C 0.0362251
PARP4 poly (ADP-ribose) polymerase family, member 4 0.0359136
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.0347807
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0346433
RIN2 Ras and Rab interactor 2 0.0330561
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 0.0327386
SH3PXD2A SH3 and PX domains 2A 0.0320833
NUMA1 nuclear mitotic apparatus protein 1 0.0319035
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.0318309
LAMA5 laminin, alpha 5 0.0314123
EZR ezrin 0.0313353
ANXA1 annexin A1 0.0313088
ANKH ANKH inorganic pyrophosphate transport regulator 0.0312768
ANXA2 annexin A2 0.0311352
EMP1 epithelial membrane protein 1 0.0310752
RASA3 RAS p21 protein activator 3 0.0307061
MBNL2 muscleblind-like splicing regulator 2 0.0305679
PGK1 phosphoglycerate kinase 1 0.0305223
CALR calreticulin 0.0304614
KRT14 keratin 14, type I 0.0301866
SUN1 Sad1 and UNC84 domain containing 1 0.0299106
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0295403
ZMIZ1 zinc finger, MIZ-type containing 1 0.0294777
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.0294424
RALGDS ral guanine nucleotide dissociation stimulator 0.0288569
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 0.02883
KIF16B kinesin family member 16B 0.0287462
ASPH aspartate beta-hydroxylase 0.028547
MCL1 myeloid cell leukemia 1 0.028364
LOXL2 lysyl oxidase-like 2 0.0282683
VEGFA vascular endothelial growth factor A 0.0280336
TPM3 tropomyosin 3 0.0278731
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0278084
EPHA2 EPH receptor A2 0.0277337
ZNF292 zinc finger protein 292 0.0275559
DOCK5 dedicator of cytokinesis 5 0.0273378
AMOTL1 angiomotin like 1 0.0272712
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 0.0271918
DIDO1 death inducer-obliterator 1 0.0270825
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0269035
MYO10 myosin X 0.0262945
SHB Src homology 2 domain containing adaptor protein B 0.0262806
PTPRF protein tyrosine phosphatase, receptor type, F 0.0262462
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.0257997
KRT17 keratin 17, type I 0.0254635
YEATS2 YEATS domain containing 2 0.0252879
RAD51B RAD51 paralog B 0.0251603
PDLIM1 PDZ and LIM domain 1 0.0249829
RPL3 ribosomal protein L3 0.0249664
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 0.0249587
SLC45A4 solute carrier family 45, member 4 0.0247454
TENM4 teneurin transmembrane protein 4 0.0244563

decreased expression

Symbol Name Standardized Value
TIMP3 TIMP metallopeptidase inhibitor 3 -0.278553
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.219675
TPT1 tumor protein, translationally-controlled 1 -0.104731
ALCAM activated leukocyte cell adhesion molecule -0.0783103
RPS24 ribosomal protein S24 -0.0474035
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -0.044517
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0375627
POTEF POTE ankyrin domain family, member F -0.0355987
RASAL2 RAS protein activator like 2 -0.0352183
GNAS GNAS complex locus -0.0348864
RPS25 ribosomal protein S25 -0.034015
S100A11 S100 calcium binding protein A11 -0.0338473
RIGI RNA sensor RIG-I -0.0330732
SAMD9 sterile alpha motif domain containing 9 -0.0329363
RAP1B RAP1B, member of RAS oncogene family -0.0326969
RPS21 ribosomal protein S21 -0.0304762
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0273962
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.0268261
SP100 SP100 nuclear antigen -0.0266263
RPL34 ribosomal protein L34 -0.0262699
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.0256422
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0251089
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0250779
PDLIM5 PDZ and LIM domain 5 -0.0248244
PITPNB phosphatidylinositol transfer protein, beta -0.0244876
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0242918
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0240767
RBM39 RNA binding motif protein 39 -0.0240385
IFI27 interferon, alpha-inducible protein 27 -0.023417
PTMA prothymosin, alpha -0.0234043
DPYD dihydropyrimidine dehydrogenase -0.0231943
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0228288
RPLP0 ribosomal protein, large, P0 -0.0222166
RPS6 ribosomal protein S6 -0.0221759
TXNRD1 thioredoxin reductase 1 -0.0216766
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 -0.0213899
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0212851
RTN4 reticulon 4 -0.0206625
ZSWIM6 zinc finger, SWIM-type containing 6 -0.020613
RPL35A ribosomal protein L35a -0.0205414
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 -0.0205052
RPLP2 ribosomal protein, large, P2 -0.0203383
PDE4D phosphodiesterase 4D, cAMP-specific -0.0200854
IFI44L interferon-induced protein 44-like -0.0200668
LDHA lactate dehydrogenase A -0.0199631
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0199238
ZNFX1 zinc finger, NFX1-type containing 1 -0.0198544
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0198306
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.0194099
RIOK3 RIO kinase 3 -0.019337
RPL27A ribosomal protein L27a -0.0191228
MX2 MX dynamin-like GTPase 2 -0.0190984
EXOC6B exocyst complex component 6B -0.0189614
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -0.0187295
ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein-like 2 -0.0185445
ARID4B AT rich interactive domain 4B (RBP1-like) -0.018386
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0183263
THBD thrombomodulin -0.0182359
FRMD4B FERM domain containing 4B -0.0182076
VDAC1 voltage-dependent anion channel 1 -0.0180806
DEK DEK proto-oncogene -0.0179217
RAB7A RAB7A, member RAS oncogene family -0.0178316
ANKRD17 ankyrin repeat domain 17 -0.0177335
DSG2 desmoglein 2 -0.0176918
NT5C2 5'-nucleotidase, cytosolic II -0.0176537
WNT2B wingless-type MMTV integration site family, member 2B -0.0174067
IFI6 interferon, alpha-inducible protein 6 -0.0173972
IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough -0.0172491
S100A10 S100 calcium binding protein A10 -0.0172029
EXT1 exostosin glycosyltransferase 1 -0.0171076
WASF2 WAS protein family, member 2 -0.0170795
RPS19 ribosomal protein S19 -0.017079
SPINK5 serine peptidase inhibitor, Kazal type 5 -0.017034
KIF5B kinesin family member 5B -0.0169251
WARS1 tryptophanyl-tRNA synthetase 1 -0.0168653
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.0168411
FTL ferritin, light polypeptide -0.0167121
RPL12 ribosomal protein L12 -0.0166693
ACTG1 actin gamma 1 -0.016603
KISS1 KiSS-1 metastasis-suppressor -0.016571
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.01648
JMJD1C jumonji domain containing 1C -0.0164041
TKT transketolase -0.0163493
MCU mitochondrial calcium uniporter -0.0163346
CDK17 cyclin-dependent kinase 17 -0.0162407
LY6E lymphocyte antigen 6 complex, locus E -0.0161818
RPL31 ribosomal protein L31 -0.016126
HLA-E major histocompatibility complex, class I, E -0.016093
CSE1L CSE1 chromosome segregation 1-like (yeast) -0.0159769
ZMYND8 zinc finger, MYND-type containing 8 -0.015875
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0157976
PALLD palladin, cytoskeletal associated protein -0.0157335
IGFBP4 insulin-like growth factor binding protein 4 -0.0156689
CSTB cystatin B (stefin B) -0.0156663
NAP1L1 nucleosome assembly protein 1-like 1 -0.0156347
CCND1 cyclin D1 -0.0155736
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.0155705
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.015555
B2M beta-2-microglobulin -0.0155381
RPS14 ribosomal protein S14 -0.0153366