Ferulic acid_J82 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Ferulic acid perturbation in J82 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Ferulic acid_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
TRIO trio Rho guanine nucleotide exchange factor 0.133694
NDRG1 N-myc downstream regulated 1 0.131905
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.103382
UGCG UDP-glucose ceramide glucosyltransferase 0.0933813
MYH9 myosin, heavy chain 9, non-muscle 0.0840669
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0794238
IGFBP3 insulin-like growth factor binding protein 3 0.0612463
VEGFA vascular endothelial growth factor A 0.0536813
FLNA filamin A, alpha 0.0516516
ATP13A3 ATPase type 13A3 0.0513471
BHLHE40 basic helix-loop-helix family, member e40 0.0508604
PODXL podocalyxin-like 0.0486539
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0473192
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0462675
ANXA2 annexin A2 0.0462479
FTH1 ferritin, heavy polypeptide 1 0.0454358
NUP58 nucleoporin 58 0.0449359
ADM adrenomedullin 0.0446528
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.044398
ANKRD11 ankyrin repeat domain 11 0.0431967
PLEC plectin 0.0424997
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0416958
WSB1 WD repeat and SOCS box containing 1 0.0413182
FLNB filamin B, beta 0.0395742
ACTN1 actinin, alpha 1 0.0386128
WAC WW domain containing adaptor with coiled-coil 0.0384507
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0384284
TSC22D2 TSC22 domain family, member 2 0.038087
SMAD3 SMAD family member 3 0.0370325
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.0363853
ANKRD10 ankyrin repeat domain 10 0.0362381
UBA6 ubiquitin-like modifier activating enzyme 6 0.0359463
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0358174
RICTOR RPTOR independent companion of MTOR, complex 2 0.0354643
NAV2 neuron navigator 2 0.0315586
SEPTIN9 septin 9 0.0312647
NCOR2 nuclear receptor corepressor 2 0.0302299
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0300901
NCOA3 nuclear receptor coactivator 3 0.0298503
TFG TRK-fused gene 0.0296548
KMT2C lysine (K)-specific methyltransferase 2C 0.0296177
ELL2 elongation factor, RNA polymerase II, 2 0.0288896
BRD2 bromodomain containing 2 0.0287953
LOC112694756 uncharaterized LOC112694756 0.0287395
SPAG9 sperm associated antigen 9 0.0286717
PGK1 phosphoglycerate kinase 1 0.0279959
ANKRD33B ankyrin repeat domain 33B 0.0278658
HILPDA hypoxia inducible lipid droplet-associated 0.0277927
QKI QKI, KH domain containing, RNA binding 0.0276101
RAB1A RAB1A, member RAS oncogene family 0.02753
TPD52 tumor protein D52 0.027468
DENND4C DENN/MADD domain containing 4C 0.0273656
RYBP RING1 and YY1 binding protein 0.0272587
MARCHF6 membrane associated ring-CH-type finger 6 0.0267037
HELZ helicase with zinc finger 0.0266083
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0263536
TPM3 tropomyosin 3 0.0262294
RAB8B RAB8B, member RAS oncogene family 0.0261168
PUM1 pumilio RNA-binding family member 1 0.0256954
ADAM9 ADAM metallopeptidase domain 9 0.0255538
NOP58 NOP58 ribonucleoprotein 0.0253237
FOXO3 forkhead box O3 0.0252142
STC2 stanniocalcin 2 0.0250577
RND3 Rho family GTPase 3 0.0250458
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0249632
DTNA dystrobrevin, alpha 0.024866
AKAP12 A kinase (PRKA) anchor protein 12 0.0246536
TRAM2 translocation associated membrane protein 2 0.0245475
ESYT2 extended synaptotagmin-like protein 2 0.0243913
RAD23B RAD23 homolog B (S. cerevisiae) 0.0243757
MSN moesin 0.0242571
POTEF POTE ankyrin domain family, member F 0.0241779
ADD1 adducin 1 (alpha) 0.0239137
RBM39 RNA binding motif protein 39 0.0234619
FGFR1 fibroblast growth factor receptor 1 0.023371
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0233644
FBXO42 F-box protein 42 0.0231644
RIOK3 RIO kinase 3 0.0230682
MAP2K1 mitogen-activated protein kinase kinase 1 0.0229682
CEP250 centrosomal protein 250kDa 0.0229678
ADARB1 adenosine deaminase, RNA-specific, B1 0.0228538
COL5A1 collagen, type V, alpha 1 0.0227609
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit 0.0225243
YEATS2 YEATS domain containing 2 0.0225221
DLG1 discs, large homolog 1 (Drosophila) 0.022404
MYH10 myosin, heavy chain 10, non-muscle 0.022291
WDR45B WD repeat domain 45B 0.0222531
PTPN14 protein tyrosine phosphatase, non-receptor type 14 0.0221728
KDM3A lysine (K)-specific demethylase 3A 0.0221486
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0220488
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 0.0220275
LENG8 leukocyte receptor cluster (LRC) member 8 0.0220065
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.021618
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.021474
USP3 ubiquitin specific peptidase 3 0.0214656
TRA2A transformer 2 alpha homolog (Drosophila) 0.0213888
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0213132
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.0212069
CXCL8 chemokine (C-X-C motif) ligand 8 0.021174
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.021103

decreased expression

Symbol Name Standardized Value
NALF1 NALCN channel auxiliary factor 1 -0.0980834
CD44 CD44 molecule (Indian blood group) -0.0616656
EXT1 exostosin glycosyltransferase 1 -0.0522535
MT2A metallothionein 2A -0.0510099
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0451948
HLA-B major histocompatibility complex, class I, B -0.0443432
CENPF centromere protein F, 350/400kDa -0.0375652
TPT1 tumor protein, translationally-controlled 1 -0.0375531
GLIS3 GLIS family zinc finger 3 -0.0358488
SMC4 structural maintenance of chromosomes 4 -0.0323965
ZBTB20 zinc finger and BTB domain containing 20 -0.032374
ASPH aspartate beta-hydroxylase -0.0316306
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0295796
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0294098
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0278162
PHLDB2 pleckstrin homology-like domain, family B, member 2 -0.0270553
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0268343
AHNAK AHNAK nucleoprotein -0.0250125
DPYD dihydropyrimidine dehydrogenase -0.0246564
RAI14 retinoic acid induced 14 -0.0245344
RPS8 ribosomal protein S8 -0.0242548
RPS6 ribosomal protein S6 -0.024119
ERBIN erbb2 interacting protein -0.0239244
HMGB1 high mobility group box 1 -0.0235795
DIAPH3 diaphanous-related formin 3 -0.0229433
OSMR oncostatin M receptor -0.0225713
TUBB tubulin, beta class I -0.0222191
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 -0.0219927
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0219346
FHIT fragile histidine triad -0.0214084
ABI3BP ABI family, member 3 (NESH) binding protein -0.0211968
MKI67 marker of proliferation Ki-67 -0.020265
VIM vimentin -0.0201078
TXNRD1 thioredoxin reductase 1 -0.0199132
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0198592
RAD51B RAD51 paralog B -0.0194169
BRCA2 breast cancer 2, early onset -0.0185812
MAP1B microtubule-associated protein 1B -0.0183772
RPL26 ribosomal protein L26 -0.0182454
RPL9 ribosomal protein L9 -0.0179643
RPS24 ribosomal protein S24 -0.0179623
PLSCR1 phospholipid scramblase 1 -0.0179346
RPL35A ribosomal protein L35a -0.0178621
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 -0.0178031
TMSB10 thymosin beta 10 -0.0175944
GOLGB1 golgin B1 -0.0174836
LPP LIM domain containing preferred translocation partner in lipoma -0.0174295
PTPRK protein tyrosine phosphatase, receptor type, K -0.0173722
EIF5B eukaryotic translation initiation factor 5B -0.0173234
CDK12 cyclin-dependent kinase 12 -0.0169513
MYL12B myosin, light chain 12B, regulatory -0.0167951
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.0164173
NABP1 nucleic acid binding protein 1 -0.0163513
STARD13 StAR-related lipid transfer (START) domain containing 13 -0.0162108
TUT7 terminal uridylyl transferase 7 -0.0161722
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0160535
LRMDA leucine rich melanocyte differentiation associated -0.0159669
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -0.0159387
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0158535
ZNF644 zinc finger protein 644 -0.015735
SCLT1 sodium channel and clathrin linker 1 -0.0153508
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -0.0153389
RPLP2 ribosomal protein, large, P2 -0.0152266
NF1 neurofibromin 1 -0.0152038
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.0151784
IFI16 interferon, gamma-inducible protein 16 -0.0151482
PARVA parvin, alpha -0.0150697
SCFD1 sec1 family domain containing 1 -0.0150489
SCAF11 SR-related CTD-associated factor 11 -0.014986
PARD3B par-3 family cell polarity regulator beta -0.0149716
PRIM2 primase, DNA, polypeptide 2 (58kDa) -0.0148706
GCC2 GRIP and coiled-coil domain containing 2 -0.014812
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0146917
DEK DEK proto-oncogene -0.0146532
VEGFC vascular endothelial growth factor C -0.0144044
PALM2AKAP2 PALM2 and AKAP2 fusion -0.0143723
ZEB2 zinc finger E-box binding homeobox 2 -0.0143058
TRIM56 tripartite motif containing 56 -0.014199
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0141338
EHBP1 EH domain binding protein 1 -0.0140992
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -0.0140768
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -0.0140637
SUMF1 sulfatase modifying factor 1 -0.0139308
SLIT2 slit homolog 2 (Drosophila) -0.0138316
LIMA1 LIM domain and actin binding 1 -0.0137354
RPL35 ribosomal protein L35 -0.01366
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0136061
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -0.0135442
TAS2R14 taste receptor, type 2, member 14 -0.0134678
WWOX WW domain containing oxidoreductase -0.0132951
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0132092
COL4A2 collagen, type IV, alpha 2 -0.0131451
NRG1 neuregulin 1 -0.0131047
EXOC4 exocyst complex component 4 -0.0130571
RHOBTB3 Rho-related BTB domain containing 3 -0.0130208
HMGN2 high mobility group nucleosomal binding domain 2 -0.0127311
BOD1L1 biorientation of chromosomes in cell division 1-like 1 -0.0126635
RPL12 ribosomal protein L12 -0.012625
TBC1D5 TBC1 domain family, member 5 -0.0126072
NSRP1 nuclear speckle splicing regulatory protein 1 -0.0125263