Ferulic acid_KATO III Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Ferulic acid perturbation in KATO III cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Ferulic acid_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
FGFR2 fibroblast growth factor receptor 2 0.111796
PLEC plectin 0.103118
MYH9 myosin, heavy chain 9, non-muscle 0.0979411
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0766413
VEGFA vascular endothelial growth factor A 0.0762565
KRT8 keratin 8, type II 0.0716582
ATXN1 ataxin 1 0.0705575
CEMIP cell migration inducing protein, hyaluronan binding 0.0685332
HYOU1 hypoxia up-regulated 1 0.0661954
KLHL29 kelch-like family member 29 0.0660651
KRT18 keratin 18, type I 0.0656174
FNDC3B fibronectin type III domain containing 3B 0.0616722
MBNL2 muscleblind-like splicing regulator 2 0.0609794
FLNB filamin B, beta 0.0585185
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0582912
FAT1 FAT atypical cadherin 1 0.0498623
ZFAND3 zinc finger, AN1-type domain 3 0.0477634
CADPS2 Ca++-dependent secretion activator 2 0.047025
ANLN anillin, actin binding protein 0.0433697
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.0433493
SMAD3 SMAD family member 3 0.0422685
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0420834
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 0.0416605
SHB Src homology 2 domain containing adaptor protein B 0.0413374
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.041259
NONO non-POU domain containing, octamer-binding 0.0407688
EXT1 exostosin glycosyltransferase 1 0.0379763
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 0.0375672
NDRG1 N-myc downstream regulated 1 0.0374396
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0372228
DSPP dentin sialophosphoprotein 0.0371022
COPG1 coatomer protein complex, subunit gamma 1 0.0370949
KMT2C lysine (K)-specific methyltransferase 2C 0.036386
FLNA filamin A, alpha 0.0357521
KIF16B kinesin family member 16B 0.0353939
MPRIP myosin phosphatase Rho interacting protein 0.0346417
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0343101
EXOC4 exocyst complex component 4 0.0340706
APLP2 amyloid beta (A4) precursor-like protein 2 0.0338738
MACF1 microtubule-actin crosslinking factor 1 0.0336762
LPP LIM domain containing preferred translocation partner in lipoma 0.0335073
CTNND1 catenin (cadherin-associated protein), delta 1 0.0331242
EEF2 eukaryotic translation elongation factor 2 0.0328701
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.0328308
BCL2L1 BCL2-like 1 0.0324568
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 0.032287
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0321631
CLTC clathrin, heavy chain (Hc) 0.0317564
INTS6 integrator complex subunit 6 0.031449
NCOR2 nuclear receptor corepressor 2 0.0312898
PMM2 phosphomannomutase 2 0.0305225
UMAD1 UBAP1-MVB12-associated (UMA) domain containing 1 0.0304527
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0302316
NFE2L1 nuclear factor, erythroid 2-like 1 0.0301727
AKAP9 A kinase (PRKA) anchor protein 9 0.030118
GRB10 growth factor receptor-bound protein 10 0.0300525
LOC112694756 uncharaterized LOC112694756 0.0297119
PRELID2 PRELI domain containing 2 0.0291917
SEPTIN9 septin 9 0.0290982
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.0290883
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.0289695
GCLC glutamate-cysteine ligase, catalytic subunit 0.0289659
PGM3 phosphoglucomutase 3 0.0285894
SRRM2 serine/arginine repetitive matrix 2 0.0283329
NUMA1 nuclear mitotic apparatus protein 1 0.0282906
GOLGA4 golgin A4 0.0281905
TBC1D22A TBC1 domain family, member 22A 0.0277702
ZNF292 zinc finger protein 292 0.0276414
LMO7 LIM domain 7 0.0275286
MYOF myoferlin 0.0274727
GIGYF2 GRB10 interacting GYF protein 2 0.0274491
ANXA11 annexin A11 0.0274112
RNASE12 ribonuclease, RNase A family, 12 (non-active) 0.027142
EIF4B eukaryotic translation initiation factor 4B 0.027044
PRDM16 PR domain containing 16 0.0267504
YEATS2 YEATS domain containing 2 0.0265098
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.026428
USP9X ubiquitin specific peptidase 9, X-linked 0.0263169
TRIM2 tripartite motif containing 2 0.0263104
GOLGB1 golgin B1 0.0262771
COG6 component of oligomeric golgi complex 6 0.026088
RAD51B RAD51 paralog B 0.0260624
ANKRD11 ankyrin repeat domain 11 0.0259265
ESRP1 epithelial splicing regulatory protein 1 0.0256986
MED15 mediator complex subunit 15 0.0254939
SEC24D SEC24 family member D 0.0254226
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0252114
ARHGAP32 Rho GTPase activating protein 32 0.0249819
HSPA8 heat shock 70kDa protein 8 0.024728
TMED2 transmembrane emp24 domain trafficking protein 2 0.0246397
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.0246354
KDM4C lysine (K)-specific demethylase 4C 0.0246193
DSCAM Down syndrome cell adhesion molecule 0.0246102
FNIP1 folliculin interacting protein 1 0.0245038
MYO18A myosin XVIIIA 0.0244384
MYO5B myosin VB 0.0243809
HELZ helicase with zinc finger 0.0242238
DOCK5 dedicator of cytokinesis 5 0.0240737
AKAP13 A kinase (PRKA) anchor protein 13 0.0240727
SND1 staphylococcal nuclease and tudor domain containing 1 0.0239972

decreased expression

Symbol Name Standardized Value
TPT1 tumor protein, translationally-controlled 1 -0.110016
PTMA prothymosin, alpha -0.106342
TMSB10 thymosin beta 10 -0.0977171
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0893456
NPSR1 neuropeptide S receptor 1 -0.0885596
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0848913
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.0770081
RPS6 ribosomal protein S6 -0.0756446
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.0711678
S100A6 S100 calcium binding protein A6 -0.0706983
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.066503
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0645979
RPL35A ribosomal protein L35a -0.0629499
POTEF POTE ankyrin domain family, member F -0.0589022
B2M beta-2-microglobulin -0.0527624
ATF5 activating transcription factor 5 -0.0480758
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.0473568
EPCAM epithelial cell adhesion molecule -0.0462604
AGR2 anterior gradient 2 -0.0458302
TMEM123 transmembrane protein 123 -0.0454961
IFI6 interferon, alpha-inducible protein 6 -0.044975
HLA-A major histocompatibility complex, class I, A -0.0433829
S100A10 S100 calcium binding protein A10 -0.0415902
LCN2 lipocalin 2 -0.0410954
RPS25 ribosomal protein S25 -0.0410944
FTL ferritin, light polypeptide -0.0408157
TMC5 transmembrane channel-like 5 -0.038469
RPLP1 ribosomal protein, large, P1 -0.0378726
IFI27 interferon, alpha-inducible protein 27 -0.0369377
RPS24 ribosomal protein S24 -0.0350188
DEK DEK proto-oncogene -0.0343576
S100A11 S100 calcium binding protein A11 -0.0343544
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0341236
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0331416
LOC102724023 ES1 protein homolog, mitochondrial -0.0321412
RPL34 ribosomal protein L34 -0.0314605
HMGB1 high mobility group box 1 -0.0305018
KPNB1 karyopherin (importin) beta 1 -0.0297889
SLC38A1 solute carrier family 38, member 1 -0.0293625
ACACA acetyl-CoA carboxylase alpha -0.0288267
RPL36A ribosomal protein L36a -0.0287577
IFITM1 interferon induced transmembrane protein 1 -0.0281643
RPS16 ribosomal protein S16 -0.0281218
TPM4 tropomyosin 4 -0.0269313
CDK6 cyclin-dependent kinase 6 -0.0253968
S100A9 S100 calcium binding protein A9 -0.0252771
CBX3 chromobox homolog 3 -0.0251899
TM4SF1 transmembrane 4 L six family member 1 -0.024772
IFITM3 interferon induced transmembrane protein 3 -0.0242319
PGK1 phosphoglycerate kinase 1 -0.023693
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.0234777
RPL23 ribosomal protein L23 -0.023472
S100P S100 calcium binding protein P -0.0233517
RPL39 ribosomal protein L39 -0.0231891
HLA-E major histocompatibility complex, class I, E -0.0231789
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -0.0229991
IER3 immediate early response 3 -0.0229956
TUBA1B tubulin, alpha 1b -0.0228222
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0227368
SOX4 SRY (sex determining region Y)-box 4 -0.0227108
ENO1 enolase 1, (alpha) -0.0223439
PERP PERP, TP53 apoptosis effector -0.0222091
DSTN destrin (actin depolymerizing factor) -0.0221881
CCND1 cyclin D1 -0.022131
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.0221148
RPS19 ribosomal protein S19 -0.0217461
MYL12B myosin, light chain 12B, regulatory -0.0214857
RPL12 ribosomal protein L12 -0.0212638
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.0212507
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0209035
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0208824
PRSS3 protease, serine, 3 -0.0208102
SP100 SP100 nuclear antigen -0.0207379
RPS21 ribosomal protein S21 -0.0206405
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0206134
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -0.0205952
DSG2 desmoglein 2 -0.0205706
INSIG1 insulin induced gene 1 -0.0205484
CD2AP CD2-associated protein -0.0204842
KLK10 kallikrein-related peptidase 10 -0.0202812
WDR45B WD repeat domain 45B -0.0202005
AGR3 anterior gradient 3 -0.0199083
RPL19 ribosomal protein L19 -0.0195454
CLDN7 claudin 7 -0.01943
RPS27A ribosomal protein S27a -0.0192542
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0192403
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0191083
AREG amphiregulin -0.019045
RPS14 ribosomal protein S14 -0.0189479
RPS8 ribosomal protein S8 -0.018862
GPX2 glutathione peroxidase 2 -0.0188288
RPL26 ribosomal protein L26 -0.018634
XAF1 XIAP associated factor 1 -0.0184696
THOC2 THO complex 2 -0.0184365
VDAC1 voltage-dependent anion channel 1 -0.0183429
RPS29 ribosomal protein S29 -0.0182395
ATP5F1B ATP synthase F1 subunit beta -0.0182322
RPL9 ribosomal protein L9 -0.0181152
RBM25 RNA binding motif protein 25 -0.0179608
ACSL4 acyl-CoA synthetase long-chain family member 4 -0.0175839