Ferulic acid_PANC-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Ferulic acid perturbation in PANC-1 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Ferulic acid_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 0.152995
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.113055
MYH9 myosin, heavy chain 9, non-muscle 0.0981282
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.091137
SEPTIN9 septin 9 0.0863584
TRIO trio Rho guanine nucleotide exchange factor 0.0828143
PLEC plectin 0.0755847
EEF2 eukaryotic translation elongation factor 2 0.073555
COL18A1 collagen, type XVIII, alpha 1 0.0658385
FBL fibrillarin 0.0625056
EGR1 early growth response 1 0.0621085
FOSL1 FOS-like antigen 1 0.0579632
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.0513714
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.0512897
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1 0.0509547
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0482565
PTMA prothymosin, alpha 0.0466221
NAV2 neuron navigator 2 0.0464424
LOC112694756 uncharaterized LOC112694756 0.0462785
YBX1 Y box binding protein 1 0.0460266
P4HB prolyl 4-hydroxylase, beta polypeptide 0.045079
NCOR2 nuclear receptor corepressor 2 0.0441321
ANKRD11 ankyrin repeat domain 11 0.0440834
TMSB10 thymosin beta 10 0.0440486
CTBP2 C-terminal binding protein 2 0.0423126
VEGFA vascular endothelial growth factor A 0.041941
FLNA filamin A, alpha 0.0412478
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 0.039998
FLNB filamin B, beta 0.03816
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 0.037104
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0369311
ADAM17 ADAM metallopeptidase domain 17 0.035998
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 0.0358592
SMAD3 SMAD family member 3 0.0354884
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.0344877
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) 0.0342176
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0340874
ZCCHC7 zinc finger, CCHC domain containing 7 0.0314267
LENG8 leukocyte receptor cluster (LRC) member 8 0.0313241
DDIT4 DNA-damage-inducible transcript 4 0.030688
RPL3 ribosomal protein L3 0.0301562
L1CAM L1 cell adhesion molecule 0.0298596
HSPG2 heparan sulfate proteoglycan 2 0.0293424
CALR calreticulin 0.0288848
BHLHE40 basic helix-loop-helix family, member e40 0.0288237
HPCAL1 hippocalcin-like 1 0.0287267
FMNL2 formin-like 2 0.0282333
NONO non-POU domain containing, octamer-binding 0.0281525
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0278809
UPP1 uridine phosphorylase 1 0.0276239
RPL23 ribosomal protein L23 0.0274139
NUP58 nucleoporin 58 0.0273919
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.0270794
PRRC2A proline-rich coiled-coil 2A 0.0266151
COPA coatomer protein complex, subunit alpha 0.026486
PTPRJ protein tyrosine phosphatase, receptor type, J 0.0253742
TNIP1 TNFAIP3 interacting protein 1 0.0251986
JUN jun proto-oncogene 0.025126
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.0246189
SREBF2 sterol regulatory element binding transcription factor 2 0.0244046
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.0240298
CD109 CD109 molecule 0.0236478
RPLP0 ribosomal protein, large, P0 0.0236219
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.0232074
CMIP c-Maf inducing protein 0.0230828
PXDN peroxidasin 0.0228008
AHDC1 AT hook, DNA binding motif, containing 1 0.0227934
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0225099
H1-0 H1.0 linker histone 0.0224973
FUS FUS RNA binding protein 0.0219146
PLAU plasminogen activator, urokinase 0.0213043
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.0212084
PRDM16 PR domain containing 16 0.0211159
ATXN2L ataxin 2-like 0.0210003
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.0206259
RASA3 RAS p21 protein activator 3 0.020608
EPHA2 EPH receptor A2 0.0205195
KRT8 keratin 8, type II 0.0205045
RACK1 receptor for activated C kinase 1 0.0204062
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.0201845
WDR43 WD repeat domain 43 0.0201576
MSN moesin 0.020037
PPDPF pancreatic progenitor cell differentiation and proliferation factor 0.0199004
TFG TRK-fused gene 0.0198813
SPAG9 sperm associated antigen 9 0.0198277
RPS10 ribosomal protein S10 0.0198226
SHB Src homology 2 domain containing adaptor protein B 0.019711
ACTN1 actinin, alpha 1 0.0194136
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0193243
USP36 ubiquitin specific peptidase 36 0.0192502
RAD23B RAD23 homolog B (S. cerevisiae) 0.0190282
NUMA1 nuclear mitotic apparatus protein 1 0.0190079
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.0190012
PKM pyruvate kinase, muscle 0.0189033
RNASE12 ribonuclease, RNase A family, 12 (non-active) 0.0187498
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.0187186
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.0186432
ARID1A AT rich interactive domain 1A (SWI-like) 0.0184446
KRT18 keratin 18, type I 0.0184118
MIDEAS mitotic deacetylase associated SANT domain protein 0.0183307

decreased expression

Symbol Name Standardized Value
AKAP12 A kinase (PRKA) anchor protein 12 -0.288379
RPS16 ribosomal protein S16 -0.150015
ERRFI1 ERBB receptor feedback inhibitor 1 -0.112782
VIM vimentin -0.108613
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0968692
ASPH aspartate beta-hydroxylase -0.087193
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.0776203
WWTR1 WW domain containing transcription regulator 1 -0.0737103
CENPF centromere protein F, 350/400kDa -0.0714994
AHNAK AHNAK nucleoprotein -0.0703738
TM4SF1 transmembrane 4 L six family member 1 -0.0678427
DST dystonin -0.0677996
RPS2 ribosomal protein S2 -0.0670008
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0660393
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0653181
JMJD1C jumonji domain containing 1C -0.0611974
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0610786
ZNF780B zinc finger protein 780B -0.0558043
BIRC2 baculoviral IAP repeat containing 2 -0.0537454
ARHGAP29 Rho GTPase activating protein 29 -0.0472901
DSTN destrin (actin depolymerizing factor) -0.0472064
SAMD4B sterile alpha motif domain containing 4B -0.046742
VCL vinculin -0.0454789
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0444008
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0426161
EFNA5 ephrin-A5 -0.0425765
ATRX alpha thalassemia/mental retardation syndrome X-linked -0.0413169
KTN1 kinectin 1 (kinesin receptor) -0.0412749
PHF14 PHD finger protein 14 -0.0411648
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0405696
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 -0.0392417
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0385573
SMYD3 SET and MYND domain containing 3 -0.0383616
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -0.0376087
BIRC3 baculoviral IAP repeat containing 3 -0.0374499
ATM ATM serine/threonine kinase -0.0373268
USP34 ubiquitin specific peptidase 34 -0.0371262
MYO9A myosin IXA -0.0371012
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0364688
VMP1 vacuole membrane protein 1 -0.0363338
SDK1 sidekick cell adhesion molecule 1 -0.0363042
SBF2 SET binding factor 2 -0.0358162
ZBTB20 zinc finger and BTB domain containing 20 -0.0353401
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0352724
LARS1 leucyl-tRNA synthetase 1 -0.0349723
MBD5 methyl-CpG binding domain protein 5 -0.034903
DSCAM Down syndrome cell adhesion molecule -0.0348032
SMC4 structural maintenance of chromosomes 4 -0.0346697
ODF2L outer dense fiber of sperm tails 2-like -0.0344739
THOC2 THO complex 2 -0.0337883
RTN4 reticulon 4 -0.0337632
TPX2 TPX2, microtubule-associated -0.0335077
NF1 neurofibromin 1 -0.0335049
TPT1 tumor protein, translationally-controlled 1 -0.0334304
GLCCI1 glucocorticoid induced 1 -0.0333874
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0330597
ZC3H12B zinc finger CCCH-type containing 12B -0.0327503
CARD18 caspase recruitment domain family, member 18 -0.032524
PNISR PNN-interacting serine/arginine-rich protein -0.0324507
CCDC88A coiled-coil domain containing 88A -0.0324225
TXNRD1 thioredoxin reductase 1 -0.0320082
ZNF292 zinc finger protein 292 -0.0317474
EHBP1 EH domain binding protein 1 -0.0309889
PDE3B phosphodiesterase 3B, cGMP-inhibited -0.0306499
CEP350 centrosomal protein 350kDa -0.0306285
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0303954
FBXL17 F-box and leucine-rich repeat protein 17 -0.0300275
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0298644
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.0297179
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.02968
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.0295379
DEK DEK proto-oncogene -0.0294795
GOLGB1 golgin B1 -0.029459
RPLP2 ribosomal protein, large, P2 -0.0291809
ANKRD12 ankyrin repeat domain 12 -0.0291556
ALCAM activated leukocyte cell adhesion molecule -0.0290193
CDK13 cyclin-dependent kinase 13 -0.0290107
UTRN utrophin -0.0288629
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0286772
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0286152
RABGAP1L RAB GTPase activating protein 1-like -0.028495
ANO6 anoctamin 6 -0.0284681
ANKHD1 ankyrin repeat and KH domain containing 1 -0.0283055
ZFR zinc finger RNA binding protein -0.0279649
BMERB1 bMERB domain containing 1 -0.0278983
FAF1 Fas (TNFRSF6) associated factor 1 -0.0277453
NT5E 5'-nucleotidase, ecto (CD73) -0.0275918
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.0274648
OSMR oncostatin M receptor -0.0274387
CD44 CD44 molecule (Indian blood group) -0.0272775
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0270817
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.027015
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0268895
SPIDR scaffolding protein involved in DNA repair -0.0268864
NIPBL Nipped-B homolog (Drosophila) -0.0268715
ANKIB1 ankyrin repeat and IBR domain containing 1 -0.0264592
ZNF638 zinc finger protein 638 -0.02635
RPL4 ribosomal protein L4 -0.0260928
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -0.0259789
RPLP1 ribosomal protein, large, P1 -0.0259134