Ferulic acid_SNU-423 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Ferulic acid perturbation in SNU-423 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Ferulic acid_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
MYH9 myosin, heavy chain 9, non-muscle 0.313935
COL6A3 collagen, type VI, alpha 3 0.232043
TRIO trio Rho guanine nucleotide exchange factor 0.198876
VEGFA vascular endothelial growth factor A 0.195772
FN1 fibronectin 1 0.157307
SOD2 superoxide dismutase 2, mitochondrial 0.151834
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1 0.140917
FRMD4A FERM domain containing 4A 0.119216
PDE10A phosphodiesterase 10A 0.114446
EEF2 eukaryotic translation elongation factor 2 0.109068
NAV2 neuron navigator 2 0.097775
TNIP1 TNFAIP3 interacting protein 1 0.0895005
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0794247
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.077088
SMAD3 SMAD family member 3 0.0726681
CADM1 cell adhesion molecule 1 0.0690242
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0638983
CEP250 centrosomal protein 250kDa 0.0635815
NONO non-POU domain containing, octamer-binding 0.063143
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.0597664
FLNA filamin A, alpha 0.0587896
MYOF myoferlin 0.0569153
ZMIZ1 zinc finger, MIZ-type containing 1 0.0556242
MSN moesin 0.0543109
MACF1 microtubule-actin crosslinking factor 1 0.0526712
FNDC3B fibronectin type III domain containing 3B 0.0525506
MLPH melanophilin 0.0505333
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0503865
SFTPA2 surfactant protein A2 0.0490737
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0481058
DST dystonin 0.046966
IGFBP3 insulin-like growth factor binding protein 3 0.0466354
COL5A1 collagen, type V, alpha 1 0.0454956
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0434781
RPS10 ribosomal protein S10 0.0433495
ATXN1 ataxin 1 0.0432389
ATP13A3 ATPase type 13A3 0.0420681
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0417437
CDH13 cadherin 13 0.041656
ARRDC3 arrestin domain containing 3 0.0411482
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.0410347
RAI14 retinoic acid induced 14 0.040439
AKAP12 A kinase (PRKA) anchor protein 12 0.0397437
NAV1 neuron navigator 1 0.038883
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.0371107
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0363176
BHLHE40 basic helix-loop-helix family, member e40 0.0363081
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0361954
RPL3 ribosomal protein L3 0.0358055
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0357941
COL8A1 collagen, type VIII, alpha 1 0.0344834
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0341928
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.033856
ZMYND8 zinc finger, MYND-type containing 8 0.033659
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0333854
FLNB filamin B, beta 0.0327548
CD44 CD44 molecule (Indian blood group) 0.0324929
PTPRJ protein tyrosine phosphatase, receptor type, J 0.0324097
LPP LIM domain containing preferred translocation partner in lipoma 0.0318798
FMNL2 formin-like 2 0.0315663
TGFBI transforming growth factor, beta-induced, 68kDa 0.0308976
MMP12 matrix metallopeptidase 12 0.0307364
PLEC plectin 0.0306245
CALR calreticulin 0.0305398
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0297876
PFKP phosphofructokinase, platelet 0.0296882
TMSB4X thymosin beta 4, X-linked 0.0295476
APP amyloid beta (A4) precursor protein 0.0294141
NDRG1 N-myc downstream regulated 1 0.0292725
PAPPA pregnancy-associated plasma protein A, pappalysin 1 0.0292472
CUL4B cullin 4B 0.0289263
SREBF2 sterol regulatory element binding transcription factor 2 0.0287843
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.0283886
ZNF292 zinc finger protein 292 0.0283864
EGFR epidermal growth factor receptor 0.0280366
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0279172
MKI67 marker of proliferation Ki-67 0.0278692
TENT5A terminal nucleotidyltransferase 5A 0.0278635
TPM3 tropomyosin 3 0.0276865
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 0.027553
WSB1 WD repeat and SOCS box containing 1 0.0274522
SEPTIN9 septin 9 0.0273915
VCAN versican 0.0272646
SLC41A2 solute carrier family 41 (magnesium transporter), member 2 0.0271168
TRAM2 translocation associated membrane protein 2 0.0271032
AFDN afadin, adherens junction formation factor 0.0269016
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.0267701
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0266595
TPM1 tropomyosin 1 (alpha) 0.0266576
SHB Src homology 2 domain containing adaptor protein B 0.0266431
TNS3 tensin 3 0.02659
RAD51B RAD51 paralog B 0.0265721
ACTN1 actinin, alpha 1 0.0265194
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0263771
C3 complement component 3 0.0263716
AMPD3 adenosine monophosphate deaminase 3 0.0256129
NUMA1 nuclear mitotic apparatus protein 1 0.02537
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.025366
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 0.025326
BACE2 beta-site APP-cleaving enzyme 2 0.025043

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.196666
VIM vimentin -0.134489
FTL ferritin, light polypeptide -0.0859375
MT2A metallothionein 2A -0.0778692
TPT1 tumor protein, translationally-controlled 1 -0.0745743
TMSB10 thymosin beta 10 -0.0637678
RPS24 ribosomal protein S24 -0.0591883
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0564897
RPL35A ribosomal protein L35a -0.0446707
BICC1 BicC family RNA binding protein 1 -0.0440389
EIF1 eukaryotic translation initiation factor 1 -0.0434208
RPS6 ribosomal protein S6 -0.0430241
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.040932
RPLP1 ribosomal protein, large, P1 -0.0408378
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0389183
PNRC1 proline-rich nuclear receptor coactivator 1 -0.0388835
RPLP2 ribosomal protein, large, P2 -0.0385208
IER3 immediate early response 3 -0.0370742
RPL36A ribosomal protein L36a -0.0333576
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.0328027
DEK DEK proto-oncogene -0.0327137
IFITM3 interferon induced transmembrane protein 3 -0.0308464
IFI16 interferon, gamma-inducible protein 16 -0.0306358
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -0.030528
VDAC1 voltage-dependent anion channel 1 -0.0304494
CTSD cathepsin D -0.0298524
RPS19 ribosomal protein S19 -0.0297295
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0294438
SLC38A2 solute carrier family 38, member 2 -0.0284222
UBC ubiquitin C -0.0283401
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0280666
RPS25 ribosomal protein S25 -0.0279886
UBE2B ubiquitin-conjugating enzyme E2B -0.0270088
NCOA7 nuclear receptor coactivator 7 -0.0268753
RPS14 ribosomal protein S14 -0.0267011
RPL7A ribosomal protein L7a -0.0259178
GPC6 glypican 6 -0.0250099
RPL28 ribosomal protein L28 -0.0246767
GNAS GNAS complex locus -0.0237842
RPS20 ribosomal protein S20 -0.0237553
RPL12 ribosomal protein L12 -0.0232996
IFI6 interferon, alpha-inducible protein 6 -0.0221306
RPL34 ribosomal protein L34 -0.022118
DSTN destrin (actin depolymerizing factor) -0.0215488
TXNIP thioredoxin interacting protein -0.0211427
RAP1B RAP1B, member of RAS oncogene family -0.0209523
RPL32 ribosomal protein L32 -0.0208608
RPL27A ribosomal protein L27a -0.0205608
IFIH1 interferon induced with helicase C domain 1 -0.0195152
RPS23 ribosomal protein S23 -0.0190026
RPL19 ribosomal protein L19 -0.0187008
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0184958
GLIPR1 GLI pathogenesis-related 1 -0.0184444
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0183916
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.0183845
IFITM1 interferon induced transmembrane protein 1 -0.0182807
B2M beta-2-microglobulin -0.0180969
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0178495
LDHA lactate dehydrogenase A -0.0175985
RPS16 ribosomal protein S16 -0.017502
MT1X metallothionein 1X -0.0173425
POTEF POTE ankyrin domain family, member F -0.0172931
ALCAM activated leukocyte cell adhesion molecule -0.01718
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.0171386
VMP1 vacuole membrane protein 1 -0.0170537
RPLP0 ribosomal protein, large, P0 -0.017045
OSMR oncostatin M receptor -0.0169864
NABP1 nucleic acid binding protein 1 -0.016888
RPL31 ribosomal protein L31 -0.0166543
VCL vinculin -0.0166244
TIMP2 TIMP metallopeptidase inhibitor 2 -0.0162555
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 -0.0162412
PHIP pleckstrin homology domain interacting protein -0.0161687
RTN4 reticulon 4 -0.0160579
RPS29 ribosomal protein S29 -0.0160046
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0159737
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0159405
RPL5 ribosomal protein L5 -0.0159221
RPS21 ribosomal protein S21 -0.0157422
ENO1 enolase 1, (alpha) -0.0156047
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0154308
RPS11 ribosomal protein S11 -0.0153843
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -0.0153194
KPNB1 karyopherin (importin) beta 1 -0.0153087
TUBA1B tubulin, alpha 1b -0.0152638
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0149424
UBB ubiquitin B -0.0148388
SGO2 shugoshin 2 -0.0148314
BTG1 B-cell translocation gene 1, anti-proliferative -0.014828
TMEM41B transmembrane protein 41B -0.0148115
TUT7 terminal uridylyl transferase 7 -0.0148025
RPL37 ribosomal protein L37 -0.0146405
SP100 SP100 nuclear antigen -0.0146335
XAF1 XIAP associated factor 1 -0.0146035
RPL15 ribosomal protein L15 -0.0145346
RPL21 ribosomal protein L21 -0.0144771
RNF24 ring finger protein 24 -0.0144762
RHOBTB3 Rho-related BTB domain containing 3 -0.0143882
PERP PERP, TP53 apoptosis effector -0.0141611
HMGB1 high mobility group box 1 -0.0140986