Ferulic acid_SW 1088 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Ferulic acid perturbation in SW 1088 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Ferulic acid_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
COL6A3 collagen, type VI, alpha 3 0.459944
MYH9 myosin, heavy chain 9, non-muscle 0.158686
HELZ helicase with zinc finger 0.0748108
COL5A1 collagen, type V, alpha 1 0.0720791
SPAG9 sperm associated antigen 9 0.0661835
ANKRD11 ankyrin repeat domain 11 0.063035
VEGFA vascular endothelial growth factor A 0.0618952
LOC112694756 uncharaterized LOC112694756 0.061521
MACF1 microtubule-actin crosslinking factor 1 0.0606068
TNIP1 TNFAIP3 interacting protein 1 0.058964
GRB10 growth factor receptor-bound protein 10 0.0565131
NAV2 neuron navigator 2 0.0552757
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.052944
APLP2 amyloid beta (A4) precursor-like protein 2 0.0527852
RASA2 RAS p21 protein activator 2 0.0516696
BHLHE40 basic helix-loop-helix family, member e40 0.0515116
PLEC plectin 0.0508926
ACSL3 acyl-CoA synthetase long-chain family member 3 0.0506211
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 0.048272
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 0.0476098
SAMD4A sterile alpha motif domain containing 4A 0.0473424
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0472179
RPS19 ribosomal protein S19 0.0467191
FLNA filamin A, alpha 0.0455307
IGFBP3 insulin-like growth factor binding protein 3 0.0450364
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.0439178
ZMIZ1 zinc finger, MIZ-type containing 1 0.0427434
EEF2 eukaryotic translation elongation factor 2 0.0426799
BACE2 beta-site APP-cleaving enzyme 2 0.0426143
COL6A2 collagen, type VI, alpha 2 0.0423607
FAM20C family with sequence similarity 20, member C 0.0416047
SND1 staphylococcal nuclease and tudor domain containing 1 0.0415719
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0414072
RAD23B RAD23 homolog B (S. cerevisiae) 0.0412276
WSB1 WD repeat and SOCS box containing 1 0.0412238
SEPTIN9 septin 9 0.0407527
KCMF1 potassium channel modulatory factor 1 0.0403848
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 0.0401846
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.039365
CDH13 cadherin 13 0.0392173
F3 coagulation factor III (thromboplastin, tissue factor) 0.0391936
AHDC1 AT hook, DNA binding motif, containing 1 0.0380543
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.036496
HAPSTR1 HUWE1 associated protein modifying stress responses 0.0361491
NUDCD3 NudC domain containing 3 0.0358539
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.035731
NCOR1 nuclear receptor corepressor 1 0.0357101
NDRG1 N-myc downstream regulated 1 0.03517
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.03409
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.0340853
WDR43 WD repeat domain 43 0.0339247
CD109 CD109 molecule 0.033912
VIM vimentin 0.0337501
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.0337413
KAZN kazrin, periplakin interacting protein 0.0337365
ANXA5 annexin A5 0.0336968
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0336954
PRSS23 protease, serine, 23 0.0336229
FEM1C fem-1 homolog c (C. elegans) 0.0335079
RPS3 ribosomal protein S3 0.0334048
LOXL2 lysyl oxidase-like 2 0.0332351
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0330476
TRIO trio Rho guanine nucleotide exchange factor 0.0330145
EIF1 eukaryotic translation initiation factor 1 0.0328664
DDIT4 DNA-damage-inducible transcript 4 0.0327799
NAMPT nicotinamide phosphoribosyltransferase 0.0327221
ECPAS Ecm29 proteasome adaptor and scaffold 0.0327122
SPPL3 signal peptide peptidase like 3 0.0326692
EGFR epidermal growth factor receptor 0.0322021
FNBP1L formin binding protein 1-like 0.0320978
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0319898
AKAP12 A kinase (PRKA) anchor protein 12 0.0317081
FSCN1 fascin actin-bundling protein 1 0.0315122
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0312934
ZNF644 zinc finger protein 644 0.0312809
SNX9 sorting nexin 9 0.0312275
FAM13A family with sequence similarity 13, member A 0.0309857
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0309376
WTAP Wilms tumor 1 associated protein 0.0309372
MCTP1 multiple C2 domains, transmembrane 1 0.0307966
NUP58 nucleoporin 58 0.030561
YBX1 Y box binding protein 1 0.0297423
IRF1 interferon regulatory factor 1 0.029246
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0292303
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.0292069
L1CAM L1 cell adhesion molecule 0.0291777
UBA6 ubiquitin-like modifier activating enzyme 6 0.0291354
UGCG UDP-glucose ceramide glucosyltransferase 0.0290717
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0290068
MIS18BP1 MIS18 binding protein 1 0.0288561
RPS17 ribosomal protein S17 0.0287797
DTNA dystrobrevin, alpha 0.0287416
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 0.0287298
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.0286315
TPI1 triosephosphate isomerase 1 0.0280956
CMIP c-Maf inducing protein 0.0279672
RPL3 ribosomal protein L3 0.0277017
FAR1 fatty acyl CoA reductase 1 0.0276898
RPL5 ribosomal protein L5 0.0274251
EIF4A1 eukaryotic translation initiation factor 4A1 0.0274241

decreased expression

Symbol Name Standardized Value
MT2A metallothionein 2A -0.227862
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.105481
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.0871509
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0839705
B2M beta-2-microglobulin -0.0799046
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0783078
ANKRD17 ankyrin repeat domain 17 -0.0704723
IGFBP7 insulin-like growth factor binding protein 7 -0.0625353
TRA2A transformer 2 alpha homolog (Drosophila) -0.0588142
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0528315
ELL2 elongation factor, RNA polymerase II, 2 -0.0517467
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0496115
FTL ferritin, light polypeptide -0.0478137
COL6A1 collagen, type VI, alpha 1 -0.0472027
TGFBI transforming growth factor, beta-induced, 68kDa -0.0468538
ZNF395 zinc finger protein 395 -0.0441077
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0426338
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0422915
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0422028
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0420882
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.0420705
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0407854
TRIP12 thyroid hormone receptor interactor 12 -0.0407747
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -0.0407717
PDIA4 protein disulfide isomerase family A, member 4 -0.0404199
GOLGA4 golgin A4 -0.0397324
SDC4 syndecan 4 -0.0386168
PSD3 pleckstrin and Sec7 domain containing 3 -0.0383882
MBNL1 muscleblind-like splicing regulator 1 -0.0381722
RNF24 ring finger protein 24 -0.0372659
MAP1B microtubule-associated protein 1B -0.0372584
STC1 stanniocalcin 1 -0.0371778
SCAF11 SR-related CTD-associated factor 11 -0.0371333
GFPT2 glutamine-fructose-6-phosphate transaminase 2 -0.0369691
WDPCP WD repeat containing planar cell polarity effector -0.0363215
TPM4 tropomyosin 4 -0.0361905
CPEB4 cytoplasmic polyadenylation element binding protein 4 -0.0357148
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0354462
AFF4 AF4/FMR2 family, member 4 -0.0354
TANK TRAF family member-associated NFKB activator -0.0352637
EFNA5 ephrin-A5 -0.0352312
TIMP1 TIMP metallopeptidase inhibitor 1 -0.035228
DSTN destrin (actin depolymerizing factor) -0.0348676
TNRC6B trinucleotide repeat containing 6B -0.0344694
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -0.034247
RPS24 ribosomal protein S24 -0.0341007
TNPO1 transportin 1 -0.0339561
RRBP1 ribosome binding protein 1 -0.0339451
TXNIP thioredoxin interacting protein -0.0338404
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 -0.0337403
MAPK8 mitogen-activated protein kinase 8 -0.0336531
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.0333118
GCC2 GRIP and coiled-coil domain containing 2 -0.0332259
FNDC3B fibronectin type III domain containing 3B -0.0329953
WNT5A wingless-type MMTV integration site family, member 5A -0.0329404
CLMP CXADR-like membrane protein -0.0323699
TVP23C-CDRT4 TVP23C-CDRT4 readthrough -0.0322008
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0321527
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase -0.0321469
POTEF POTE ankyrin domain family, member F -0.0316634
CALD1 caldesmon 1 -0.0316125
ZBTB20 zinc finger and BTB domain containing 20 -0.0315534
AKAP9 A kinase (PRKA) anchor protein 9 -0.0315188
PNPLA8 patatin-like phospholipase domain containing 8 -0.0314131
RPS2 ribosomal protein S2 -0.0311546
LEPROT leptin receptor overlapping transcript -0.0305954
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -0.0298057
PTN pleiotrophin -0.029686
PTPN1 protein tyrosine phosphatase, non-receptor type 1 -0.0294014
RSRP1 arginine/serine-rich protein 1 -0.0292008
MT1X metallothionein 1X -0.0289495
SEC31A SEC31 homolog A (S. cerevisiae) -0.0288904
TMEM59 transmembrane protein 59 -0.0288512
LMAN2 lectin, mannose-binding 2 -0.0288318
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.0287259
IFRD1 interferon-related developmental regulator 1 -0.0287245
RAB31 RAB31, member RAS oncogene family -0.0286719
MAML3 mastermind-like 3 (Drosophila) -0.0284746
RB1CC1 RB1-inducible coiled-coil 1 -0.0282637
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0282032
LDHA lactate dehydrogenase A -0.0281113
RUNX1 runt-related transcription factor 1 -0.0280007
BASP1 brain abundant, membrane attached signal protein 1 -0.0279341
EXT1 exostosin glycosyltransferase 1 -0.0277944
CAMTA1 calmodulin binding transcription activator 1 -0.0277905
TMF1 TATA element modulatory factor 1 -0.0277817
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.0276916
TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast) -0.0274855
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -0.0274729
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0272288
CANX calnexin -0.027185
ZEB1 zinc finger E-box binding homeobox 1 -0.0270609
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -0.0270059
SYNRG synergin, gamma -0.0269387
PRRC1 proline-rich coiled-coil 1 -0.026918
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -0.0266487
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -0.026642
ASPH aspartate beta-hydroxylase -0.0263164
CAV1 caveolin 1, caveolae protein, 22kDa -0.0261651
ITGAV integrin, alpha V -0.0260462