Ferulic acid_SW 1271 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Ferulic acid perturbation in SW 1271 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Ferulic acid_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
PTMA prothymosin, alpha 0.104261
MYH9 myosin, heavy chain 9, non-muscle 0.0985808
EEF2 eukaryotic translation elongation factor 2 0.0882245
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0876615
PKM pyruvate kinase, muscle 0.0748091
BHLHE40 basic helix-loop-helix family, member e40 0.0701111
WAC WW domain containing adaptor with coiled-coil 0.0671392
NUP58 nucleoporin 58 0.0667631
CEP250 centrosomal protein 250kDa 0.065272
SET SET nuclear proto-oncogene 0.0611359
SPAG9 sperm associated antigen 9 0.0602066
ZNF292 zinc finger protein 292 0.0599448
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0596367
NAMPT nicotinamide phosphoribosyltransferase 0.0558101
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0554519
MSN moesin 0.0550092
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0524759
MACF1 microtubule-actin crosslinking factor 1 0.0512132
RPL23 ribosomal protein L23 0.0509484
HOOK2 hook microtubule-tethering protein 2 0.0470084
FLNA filamin A, alpha 0.0467408
HILPDA hypoxia inducible lipid droplet-associated 0.0462
TPX2 TPX2, microtubule-associated 0.0447201
NUMA1 nuclear mitotic apparatus protein 1 0.0444489
SMAD3 SMAD family member 3 0.0440707
RAD23B RAD23 homolog B (S. cerevisiae) 0.0431215
GOLGA4 golgin A4 0.0428891
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0425954
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0410979
NAP1L1 nucleosome assembly protein 1-like 1 0.0407926
TNIP1 TNFAIP3 interacting protein 1 0.0405454
ANKRD11 ankyrin repeat domain 11 0.0397879
CALR calreticulin 0.0395016
ITCH itchy E3 ubiquitin protein ligase 0.0393303
FMNL2 formin-like 2 0.0392271
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0391929
TRIO trio Rho guanine nucleotide exchange factor 0.038959
NDRG1 N-myc downstream regulated 1 0.0378349
PDPK1 3-phosphoinositide dependent protein kinase 1 0.0372279
APP amyloid beta (A4) precursor protein 0.0365611
NCAPD2 non-SMC condensin I complex, subunit D2 0.0361756
PRRC2C proline-rich coiled-coil 2C 0.0357136
RPL32 ribosomal protein L32 0.0355215
ATP13A3 ATPase type 13A3 0.0352774
BAZ2A bromodomain adjacent to zinc finger domain, 2A 0.0344866
CSNK1A1 casein kinase 1, alpha 1 0.0335538
NAV2 neuron navigator 2 0.0332694
EIF1 eukaryotic translation initiation factor 1 0.0331983
SREK1 splicing regulatory glutamine/lysine-rich protein 1 0.0331503
XRN2 5'-3' exoribonuclease 2 0.0329057
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0325043
NONO non-POU domain containing, octamer-binding 0.031906
ARRDC3 arrestin domain containing 3 0.0316138
COLEC11 collectin sub-family member 11 0.0309258
PYGL phosphorylase, glycogen, liver 0.0308753
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0305942
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0303495
MPRIP myosin phosphatase Rho interacting protein 0.0302694
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0298767
KMT2D lysine (K)-specific methyltransferase 2D 0.0293692
NBAS neuroblastoma amplified sequence 0.0293037
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0291743
ELP2 elongator acetyltransferase complex subunit 2 0.0289889
RACK1 receptor for activated C kinase 1 0.0288837
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0286682
B2M beta-2-microglobulin 0.0285402
EIF4A1 eukaryotic translation initiation factor 4A1 0.0285024
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0278623
NKTR natural killer cell triggering receptor 0.0277073
TNPO1 transportin 1 0.0276156
MKI67 marker of proliferation Ki-67 0.0275524
ESYT2 extended synaptotagmin-like protein 2 0.027521
ANXA2 annexin A2 0.0274735
FUS FUS RNA binding protein 0.0270697
GIGYF2 GRB10 interacting GYF protein 2 0.0269451
MAP2K1 mitogen-activated protein kinase kinase 1 0.0269066
FXR1 fragile X mental retardation, autosomal homolog 1 0.0268598
PEAK1 pseudopodium-enriched atypical kinase 1 0.0266036
TFG TRK-fused gene 0.0264223
ENO1 enolase 1, (alpha) 0.0263365
RPS3 ribosomal protein S3 0.026328
TM9SF2 transmembrane 9 superfamily member 2 0.0262655
RPS17 ribosomal protein S17 0.0262334
SHB Src homology 2 domain containing adaptor protein B 0.0260853
TPM3 tropomyosin 3 0.0260698
MARCHF6 membrane associated ring-CH-type finger 6 0.0259917
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.0259713
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 0.0258091
TTK TTK protein kinase 0.0255651
PNN pinin, desmosome associated protein 0.0255561
LUC7L2 LUC7-like 2 (S. cerevisiae) 0.0254823
MATR3 matrin 3 0.0254409
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.025173
ANXA5 annexin A5 0.0251551
MYLIP myosin regulatory light chain interacting protein 0.0250864
FUBP1 far upstream element (FUSE) binding protein 1 0.0250642
GGNBP2 gametogenetin binding protein 2 0.0249492
SPAG5 sperm associated antigen 5 0.0249473
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.02491
HSPA8 heat shock 70kDa protein 8 0.0248243

decreased expression

Symbol Name Standardized Value
TPT1 tumor protein, translationally-controlled 1 -0.0507437
PNRC1 proline-rich nuclear receptor coactivator 1 -0.0503899
HMGA2 high mobility group AT-hook 2 -0.0491532
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.0438903
RIGI RNA sensor RIG-I -0.038162
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0373577
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.0367963
USP34 ubiquitin specific peptidase 34 -0.0360275
ZBTB20 zinc finger and BTB domain containing 20 -0.0358939
PHLDB2 pleckstrin homology-like domain, family B, member 2 -0.0323125
PRH1 proline-rich protein HaeIII subfamily 1 -0.0313546
SMC4 structural maintenance of chromosomes 4 -0.030838
EFNA5 ephrin-A5 -0.0305947
ATM ATM serine/threonine kinase -0.0299252
VCL vinculin -0.029811
ZC3H12C zinc finger CCCH-type containing 12C -0.0296931
MBD5 methyl-CpG binding domain protein 5 -0.0296929
SCAPER S-phase cyclin A-associated protein in the ER -0.0296674
OASL 2'-5'-oligoadenylate synthetase-like -0.0286011
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0285075
GCC2 GRIP and coiled-coil domain containing 2 -0.0277951
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -0.027745
CDK13 cyclin-dependent kinase 13 -0.0276305
IER3 immediate early response 3 -0.0266486
PCNX4 pecanex 4 -0.0262492
ETF1 eukaryotic translation termination factor 1 -0.0260877
JMJD1C jumonji domain containing 1C -0.0251221
BTG1 B-cell translocation gene 1, anti-proliferative -0.0246969
CD44 CD44 molecule (Indian blood group) -0.0244193
AHNAK AHNAK nucleoprotein -0.0242013
BASP1 brain abundant, membrane attached signal protein 1 -0.0240935
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0239595
FBXL2 F-box and leucine-rich repeat protein 2 -0.0238921
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.0237299
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0237103
BPTF bromodomain PHD finger transcription factor -0.0236875
ATG12 autophagy related 12 -0.0236639
BIRC2 baculoviral IAP repeat containing 2 -0.0226347
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB -0.0224917
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0224102
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -0.0221567
STXBP5 syntaxin binding protein 5 (tomosyn) -0.0215531
GPATCH2L G patch domain containing 2-like -0.0213835
FER fer (fps/fes related) tyrosine kinase -0.0212862
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0210049
SVIL supervillin -0.020997
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0209639
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.020848
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.0208104
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -0.0206396
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0205804
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0204126
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.0201508
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -0.0198184
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0196087
INTS6 integrator complex subunit 6 -0.0195497
PCED1B PC-esterase domain containing 1B -0.0195276
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0194995
BBX bobby sox homolog (Drosophila) -0.0194914
PTPRK protein tyrosine phosphatase, receptor type, K -0.019419
DENND5B DENN/MADD domain containing 5B -0.0192964
HLA-C major histocompatibility complex, class I, C -0.0192649
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0192457
IRF2BP2 interferon regulatory factor 2 binding protein 2 -0.0190435
SLC38A2 solute carrier family 38, member 2 -0.0189995
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.0188212
RTN4 reticulon 4 -0.0187855
LRP6 low density lipoprotein receptor-related protein 6 -0.0187019
SETX senataxin -0.0185311
PARP4 poly (ADP-ribose) polymerase family, member 4 -0.0185133
NLK nemo-like kinase -0.018421
FTH1 ferritin, heavy polypeptide 1 -0.0183969
MARCHF4 membrane associated ring-CH-type finger 4 -0.0182349
NALCN sodium leak channel, non selective -0.0181908
LDHA lactate dehydrogenase A -0.0180323
TES testin LIM domain protein -0.0178823
ZBTB38 zinc finger and BTB domain containing 38 -0.0177761
MYO9A myosin IXA -0.0177659
ARF4 ADP-ribosylation factor 4 -0.0177445
MTREX Mtr4 exosome RNA helicase -0.0177184
EPC2 enhancer of polycomb homolog 2 (Drosophila) -0.0173538
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.0173531
IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough -0.0173308
PGGT1B protein geranylgeranyltransferase type I, beta subunit -0.0170033
NCEH1 neutral cholesterol ester hydrolase 1 -0.0169025
ZNF721 zinc finger protein 721 -0.0168787
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0168447
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0167223
STARD4 StAR-related lipid transfer (START) domain containing 4 -0.0166808
TUT7 terminal uridylyl transferase 7 -0.0166232
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 -0.0166232
BZW1 basic leucine zipper and W2 domains 1 -0.0165849
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0165656
PHF14 PHD finger protein 14 -0.0164883
TOP6BL TOP6B like initiator of meiotic double strand breaks -0.0162941
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -0.0162352
TOM1L2 target of myb1-like 2 (chicken) -0.0162068
HDLBP high density lipoprotein binding protein -0.0161565
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0161253
COMMD10 COMM domain containing 10 -0.0160766