Ferulic acid_SW 900 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Ferulic acid perturbation in SW 900 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Ferulic acid_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
NDRG1 N-myc downstream regulated 1 0.194247
VEGFA vascular endothelial growth factor A 0.166082
MYH9 myosin, heavy chain 9, non-muscle 0.0694325
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0693406
BHLHE40 basic helix-loop-helix family, member e40 0.0686704
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0660804
TRIO trio Rho guanine nucleotide exchange factor 0.0625859
STC2 stanniocalcin 2 0.0577877
FAM13A family with sequence similarity 13, member A 0.0561565
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0544239
HLA-B major histocompatibility complex, class I, B 0.0505224
FTH1 ferritin, heavy polypeptide 1 0.0503486
GLUL glutamate-ammonia ligase 0.0473935
SMOX spermine oxidase 0.0446402
SFTPA2 surfactant protein A2 0.0444418
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0434071
SHB Src homology 2 domain containing adaptor protein B 0.043307
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.043205
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0411666
GRB10 growth factor receptor-bound protein 10 0.0407506
ZMIZ1 zinc finger, MIZ-type containing 1 0.0402288
RPL37A ribosomal protein L37a 0.0397479
PLEC plectin 0.0389883
RICTOR RPTOR independent companion of MTOR, complex 2 0.0386243
UBA6 ubiquitin-like modifier activating enzyme 6 0.0377888
DDIT4 DNA-damage-inducible transcript 4 0.0377552
FLNA filamin A, alpha 0.0377552
TNIP1 TNFAIP3 interacting protein 1 0.0374338
MACF1 microtubule-actin crosslinking factor 1 0.037185
ESYT2 extended synaptotagmin-like protein 2 0.0367047
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0360585
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0347833
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0347517
RACK1 receptor for activated C kinase 1 0.0347073
GPC6 glypican 6 0.0342389
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0341089
IRAK3 interleukin-1 receptor-associated kinase 3 0.0338983
MED15 mediator complex subunit 15 0.0334362
NUMA1 nuclear mitotic apparatus protein 1 0.0323724
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0319581
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0318891
SMAD3 SMAD family member 3 0.0318345
EYA1 EYA transcriptional coactivator and phosphatase 1 0.0316975
PRRC2C proline-rich coiled-coil 2C 0.031657
COPA coatomer protein complex, subunit alpha 0.031643
RBM39 RNA binding motif protein 39 0.0315055
PRELID2 PRELI domain containing 2 0.0314109
TMSB4X thymosin beta 4, X-linked 0.0313077
HILPDA hypoxia inducible lipid droplet-associated 0.0310779
RPL35A ribosomal protein L35a 0.0310722
FAM20C family with sequence similarity 20, member C 0.030656
RPL3 ribosomal protein L3 0.0301399
FAT1 FAT atypical cadherin 1 0.0299319
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0296352
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.0287317
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.0286017
HELZ helicase with zinc finger 0.0285289
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 0.0285238
RPL11 ribosomal protein L11 0.0283046
TBC1D22A TBC1 domain family, member 22A 0.027839
PNN pinin, desmosome associated protein 0.0276285
FOSL1 FOS-like antigen 1 0.0271208
PPDPF pancreatic progenitor cell differentiation and proliferation factor 0.0268201
ACADVL acyl-CoA dehydrogenase, very long chain 0.0265805
SNX13 sorting nexin 13 0.026377
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.0261409
GUK1 guanylate kinase 1 0.025456
RPL38 ribosomal protein L38 0.0254089
MIDEAS mitotic deacetylase associated SANT domain protein 0.0249046
RNF145 ring finger protein 145 0.0247302
RPS27 ribosomal protein S27 0.0247258
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase) 0.0246244
PGK1 phosphoglycerate kinase 1 0.0245313
KMT2C lysine (K)-specific methyltransferase 2C 0.0244995
AFDN afadin, adherens junction formation factor 0.0242438
CEP250 centrosomal protein 250kDa 0.0242283
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1 0.0241215
WDR45B WD repeat domain 45B 0.0239928
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.0239146
TMED9 transmembrane emp24 protein transport domain containing 9 0.0238976
NCOR2 nuclear receptor corepressor 2 0.0238362
CFB complement factor B 0.0237783
FLNB filamin B, beta 0.0234885
LMNA lamin A/C 0.0233579
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.0232812
RAB6A RAB6A, member RAS oncogene family 0.0232375
HLA-C major histocompatibility complex, class I, C 0.0228
RPL36 ribosomal protein L36 0.022754
RPS26 ribosomal protein S26 0.0225169
NONO non-POU domain containing, octamer-binding 0.0224881
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 0.0223898
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0223687
UBE2H ubiquitin-conjugating enzyme E2H 0.022199
ANGPTL4 angiopoietin-like 4 0.0221429
USP36 ubiquitin specific peptidase 36 0.0221297
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0220517
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0220139
CNOT4 CCR4-NOT transcription complex, subunit 4 0.0219838
YEATS2 YEATS domain containing 2 0.0217615
CLMN calmin (calponin-like, transmembrane) 0.0217333

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.170681
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.156346
UBC ubiquitin C -0.145053
ASPH aspartate beta-hydroxylase -0.102671
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0828475
VIM vimentin -0.0791532
FN1 fibronectin 1 -0.0787183
EXT1 exostosin glycosyltransferase 1 -0.0784138
CANX calnexin -0.0776685
TMEM156 transmembrane protein 156 -0.0702141
SQSTM1 sequestosome 1 -0.0697486
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.0693319
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0692047
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0657295
ITGA1 integrin, alpha 1 -0.0640402
VCL vinculin -0.0637996
RPS27A ribosomal protein S27a -0.0612126
NRG1 neuregulin 1 -0.0603038
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0589519
AHNAK AHNAK nucleoprotein -0.0586721
SYT1 synaptotagmin I -0.0585671
S100A6 S100 calcium binding protein A6 -0.0583007
PDE4D phosphodiesterase 4D, cAMP-specific -0.057693
PCBP2 poly(rC) binding protein 2 -0.0541742
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0493735
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.0492166
ENO1 enolase 1, (alpha) -0.0485279
SVIL supervillin -0.0479239
MAP1B microtubule-associated protein 1B -0.0468618
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0467121
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0462338
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0451784
TXNRD1 thioredoxin reductase 1 -0.0440986
NFE2L2 nuclear factor, erythroid 2-like 2 -0.041794
IFI16 interferon, gamma-inducible protein 16 -0.0417103
SPDYA speedy/RINGO cell cycle regulator family member A -0.0412301
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0410652
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0404681
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.039994
VMP1 vacuole membrane protein 1 -0.0398852
OSMR oncostatin M receptor -0.039735
AHR aryl hydrocarbon receptor -0.039619
MBD5 methyl-CpG binding domain protein 5 -0.0383545
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0382479
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0382153
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -0.0378589
KLHL5 kelch-like family member 5 -0.0375558
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0370394
TXNIP thioredoxin interacting protein -0.0370103
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.0369695
IER3 immediate early response 3 -0.0366536
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 -0.0364414
AEBP2 AE binding protein 2 -0.0359233
BICD1 bicaudal D homolog 1 (Drosophila) -0.0357583
FOXP1 forkhead box P1 -0.0357316
CALU calumenin -0.035643
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0350496
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0349423
NCOA7 nuclear receptor coactivator 7 -0.0347565
RAB10 RAB10, member RAS oncogene family -0.0346955
GCC2 GRIP and coiled-coil domain containing 2 -0.0342669
PDIA4 protein disulfide isomerase family A, member 4 -0.0341787
ANKRD28 ankyrin repeat domain 28 -0.0341258
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0334988
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0332589
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -0.0312415
FNDC3A fibronectin type III domain containing 3A -0.030974
ETV1 ets variant 1 -0.0308527
CAPN2 calpain 2, (m/II) large subunit -0.0307787
SLC38A2 solute carrier family 38, member 2 -0.0303735
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0303621
ATF6 activating transcription factor 6 -0.0298294
RPS24 ribosomal protein S24 -0.0297631
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -0.0296281
TPT1 tumor protein, translationally-controlled 1 -0.029386
ZC3H12C zinc finger CCCH-type containing 12C -0.0292323
SMYD3 SET and MYND domain containing 3 -0.0288626
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0286239
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.0283642
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.0282796
POTEF POTE ankyrin domain family, member F -0.0280188
DSG2 desmoglein 2 -0.027914
SOS1 son of sevenless homolog 1 (Drosophila) -0.02787
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0277433
ZBTB20 zinc finger and BTB domain containing 20 -0.0276776
CENPF centromere protein F, 350/400kDa -0.027568
ANKRD17 ankyrin repeat domain 17 -0.0275534
THBS1 thrombospondin 1 -0.0275508
NRP1 neuropilin 1 -0.0275461
MBNL1 muscleblind-like splicing regulator 1 -0.0275139
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -0.0269618
PALLD palladin, cytoskeletal associated protein -0.0266003
FRYL FRY-like -0.0263061
USP34 ubiquitin specific peptidase 34 -0.0260706
TAS2R14 taste receptor, type 2, member 14 -0.0257343
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.0255635
RHOA ras homolog family member A -0.0255028
HMGA2 high mobility group AT-hook 2 -0.025217
SP100 SP100 nuclear antigen -0.0251562
RANBP17 RAN binding protein 17 -0.0251344