Ferulic acid_SW48 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Ferulic acid perturbation in SW48 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Ferulic acid_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
EEF2 eukaryotic translation elongation factor 2 0.0900773
ANXA1 annexin A1 0.0887094
AREG amphiregulin 0.086026
PDE4B phosphodiesterase 4B, cAMP-specific 0.076417
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0729923
CD36 CD36 molecule (thrombospondin receptor) 0.0687832
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0654839
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0621519
PTMA prothymosin, alpha 0.0612248
LMO7 LIM domain 7 0.059044
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0588209
NDRG1 N-myc downstream regulated 1 0.0514135
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.0493399
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0489276
ITPRID2 ITPR interacting domain containing 2 0.0467003
PLAUR plasminogen activator, urokinase receptor 0.0451414
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0434051
EZR ezrin 0.043193
GARS1 glycyl-tRNA synthetase 1 0.0430132
KMT2C lysine (K)-specific methyltransferase 2C 0.042265
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0421068
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0416956
GOLGA4 golgin A4 0.0413652
RNF43 ring finger protein 43 0.0411596
RUNX2 runt-related transcription factor 2 0.0399093
TXNRD1 thioredoxin reductase 1 0.0398969
WAC WW domain containing adaptor with coiled-coil 0.0394934
NUP58 nucleoporin 58 0.0393844
HSPA8 heat shock 70kDa protein 8 0.0392285
HILPDA hypoxia inducible lipid droplet-associated 0.0384535
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0383801
RPL3 ribosomal protein L3 0.0382083
KDM6A lysine (K)-specific demethylase 6A 0.0377664
TOP1 topoisomerase (DNA) I 0.0375468
EREG epiregulin 0.0373251
NAMPT nicotinamide phosphoribosyltransferase 0.0367407
DDIT4 DNA-damage-inducible transcript 4 0.0354695
OXR1 oxidation resistance 1 0.0348443
MYH9 myosin, heavy chain 9, non-muscle 0.0322704
EPHA2 EPH receptor A2 0.0320149
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.0319394
ZNF292 zinc finger protein 292 0.0319057
FAT1 FAT atypical cadherin 1 0.0318499
YBX1 Y box binding protein 1 0.0314535
PKM pyruvate kinase, muscle 0.0304162
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0301824
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0300213
WDR43 WD repeat domain 43 0.0299934
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0295599
MYO5B myosin VB 0.0292701
LAMB3 laminin, beta 3 0.0290107
AXIN2 axin 2 0.0287252
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.0282431
KDM3A lysine (K)-specific demethylase 3A 0.0280514
SLMAP sarcolemma associated protein 0.0280002
USP3 ubiquitin specific peptidase 3 0.0277706
RBM39 RNA binding motif protein 39 0.027513
TSC22D2 TSC22 domain family, member 2 0.0274325
PRRC2C proline-rich coiled-coil 2C 0.0273104
RLF rearranged L-myc fusion 0.0272692
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.0272045
OGA O-GlcNAcase 0.0268146
RNF145 ring finger protein 145 0.0266338
MARCHF6 membrane associated ring-CH-type finger 6 0.0265992
COPA coatomer protein complex, subunit alpha 0.0265843
EIF3E eukaryotic translation initiation factor 3, subunit E 0.0261527
DSPP dentin sialophosphoprotein 0.0258552
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0258298
RPS3 ribosomal protein S3 0.0255759
LDHA lactate dehydrogenase A 0.0254608
UBA6 ubiquitin-like modifier activating enzyme 6 0.0253211
GCLC glutamate-cysteine ligase, catalytic subunit 0.0252416
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.0250969
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.0248981
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.0248439
ANXA2 annexin A2 0.0247369
ESYT2 extended synaptotagmin-like protein 2 0.024601
TXNIP thioredoxin interacting protein 0.0245707
NPEPPS aminopeptidase puromycin sensitive 0.024532
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.024502
STRN3 striatin, calmodulin binding protein 3 0.0243629
COG5 component of oligomeric golgi complex 5 0.0243422
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0242879
LAMC2 laminin, gamma 2 0.0242299
FAR1 fatty acyl CoA reductase 1 0.0241881
RPL23 ribosomal protein L23 0.0237322
CSNK1A1 casein kinase 1, alpha 1 0.0234947
ZMYM2 zinc finger, MYM-type 2 0.023437
RPL26 ribosomal protein L26 0.023432
ARRDC3 arrestin domain containing 3 0.0231976
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.0231487
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0229928
ARL5B ADP-ribosylation factor-like 5B 0.0228734
MAP3K2 mitogen-activated protein kinase kinase kinase 2 0.022821
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0227937
PUM2 pumilio RNA-binding family member 2 0.0226235
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.0225534
NCKAP1 NCK-associated protein 1 0.0223513
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.0215946
FHIP1A FHF complex subunit HOOK interacting protein 1A 0.02155

decreased expression

Symbol Name Standardized Value
HMGA2 high mobility group AT-hook 2 -0.09852
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0955176
FHIT fragile histidine triad -0.0764045
RAD51B RAD51 paralog B -0.0670842
ACTG1 actin gamma 1 -0.0603987
FRAS1 Fraser extracellular matrix complex subunit 1 -0.057349
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0513885
VCL vinculin -0.0463614
CCSER1 coiled-coil serine-rich protein 1 -0.0452104
LAMA4 laminin, alpha 4 -0.0412845
RCOR1 REST corepressor 1 -0.0373777
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0361859
EXOC4 exocyst complex component 4 -0.0340856
CUX1 cut-like homeobox 1 -0.0313181
PHF14 PHD finger protein 14 -0.0301086
GPHN gephyrin -0.0290111
SLCO1B3-SLCO1B7 SLCO1B3-SLCO1B7 readthrough -0.0272463
LOC102724023 ES1 protein homolog, mitochondrial -0.0262298
EHBP1 EH domain binding protein 1 -0.0260641
MTAP methylthioadenosine phosphorylase -0.0260065
SKAP1 src kinase associated phosphoprotein 1 -0.0259563
DOCK5 dedicator of cytokinesis 5 -0.0258727
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0254726
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.0250937
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 -0.0248529
CMIP c-Maf inducing protein -0.0237618
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0233353
SMYD3 SET and MYND domain containing 3 -0.023195
CDK13 cyclin-dependent kinase 13 -0.0231105
GPC5 glypican 5 -0.0205316
BPTF bromodomain PHD finger transcription factor -0.0201167
ZBTB20 zinc finger and BTB domain containing 20 -0.0197811
RPL35A ribosomal protein L35a -0.0196227
PARD3B par-3 family cell polarity regulator beta -0.019515
ABR active BCR-related -0.0193998
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0189992
TENM3 teneurin transmembrane protein 3 -0.018974
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0189384
GLCCI1 glucocorticoid induced 1 -0.0184532
RPL31 ribosomal protein L31 -0.0179375
ITGB4 integrin, beta 4 -0.0178764
DOCK1 dedicator of cytokinesis 1 -0.0175727
DIAPH2 diaphanous-related formin 2 -0.0169057
ANKRD17 ankyrin repeat domain 17 -0.0168791
TTC3 tetratricopeptide repeat domain 3 -0.0168739
COMMD10 COMM domain containing 10 -0.0166279
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0164716
AK1 adenylate kinase 1 -0.0164228
ASPH aspartate beta-hydroxylase -0.0163263
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0163201
EGFR epidermal growth factor receptor -0.0161725
TAS2R14 taste receptor, type 2, member 14 -0.016151
PATJ PATJ crumbs cell polarity complex component -0.0161371
WWOX WW domain containing oxidoreductase -0.0160686
CDHR3 cadherin-related family member 3 -0.0160331
BICD1 bicaudal D homolog 1 (Drosophila) -0.0158968
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0157945
UBAP2 ubiquitin associated protein 2 -0.0157452
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -0.0157015
CREB5 cAMP responsive element binding protein 5 -0.0155193
PRELID2 PRELI domain containing 2 -0.0153253
TNS3 tensin 3 -0.0150986
SGMS2 sphingomyelin synthase 2 -0.0148607
TPT1 tumor protein, translationally-controlled 1 -0.0145568
ERC1 ELKS/RAB6-interacting/CAST family member 1 -0.014403
RABGAP1L RAB GTPase activating protein 1-like -0.0143109
LGALS12 lectin, galactoside-binding, soluble, 12 -0.0142635
RASAL2 RAS protein activator like 2 -0.0142135
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.0140467
PCNX4 pecanex 4 -0.0139914
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0139186
SPIDR scaffolding protein involved in DNA repair -0.0135557
IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough -0.0132521
FAF1 Fas (TNFRSF6) associated factor 1 -0.0132462
INTS6 integrator complex subunit 6 -0.0132273
KLK10 kallikrein-related peptidase 10 -0.0132227
ATP5F1B ATP synthase F1 subunit beta -0.0131715
SCMH1 sex comb on midleg homolog 1 (Drosophila) -0.0130848
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0130729
SGPP2 sphingosine-1-phosphate phosphatase 2 -0.0130264
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.013024
CCND1 cyclin D1 -0.0129352
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 -0.0127964
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -0.0127944
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.0127886
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -0.0127818
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) -0.0127021
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.0126345
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0126236
MAML3 mastermind-like 3 (Drosophila) -0.0125388
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 -0.0125057
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) -0.0124492
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 -0.012433
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0124241
KANK1 KN motif and ankyrin repeat domains 1 -0.0123793
ZNF638 zinc finger protein 638 -0.0123116
LPP LIM domain containing preferred translocation partner in lipoma -0.0123052
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -0.0122856
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0122038
AKAP13 A kinase (PRKA) anchor protein 13 -0.012187