Ferulic acid_SW480 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Ferulic acid perturbation in SW480 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Ferulic acid_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.117559
PLEC plectin 0.109602
NKD1 naked cuticle homolog 1 (Drosophila) 0.103488
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.103359
HDAC4 histone deacetylase 4 0.0929067
NAV2 neuron navigator 2 0.0832885
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.080582
ATXN1 ataxin 1 0.0691483
MYH9 myosin, heavy chain 9, non-muscle 0.0677114
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.0625205
EEF2 eukaryotic translation elongation factor 2 0.0589317
TNS3 tensin 3 0.0545075
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0540655
KRT8 keratin 8, type II 0.0530115
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.052963
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0502367
AOPEP aminopeptidase O (putative) 0.0492618
ASPH aspartate beta-hydroxylase 0.0489022
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0481409
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.046075
ANLN anillin, actin binding protein 0.0442688
FYN FYN proto-oncogene, Src family tyrosine kinase 0.0427926
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0416741
ACTN4 actinin, alpha 4 0.0413208
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.041123
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0410412
ABHD2 abhydrolase domain containing 2 0.0410393
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0407805
ESYT2 extended synaptotagmin-like protein 2 0.0402314
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0401111
FLNA filamin A, alpha 0.0399739
NONO non-POU domain containing, octamer-binding 0.038962
SMAD3 SMAD family member 3 0.0387517
TBC1D22A TBC1 domain family, member 22A 0.0382835
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0372542
CEMIP2 cell migration inducing hyaluronidase 2 0.0371249
DSPP dentin sialophosphoprotein 0.0371025
USP9X ubiquitin specific peptidase 9, X-linked 0.0358384
KDM6A lysine (K)-specific demethylase 6A 0.0357185
VGLL4 vestigial-like family member 4 0.0355007
MACF1 microtubule-actin crosslinking factor 1 0.0354791
WWOX WW domain containing oxidoreductase 0.0353696
MSI2 musashi RNA-binding protein 2 0.0352283
AXIN2 axin 2 0.0347883
SEPTIN9 septin 9 0.0347108
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.0344886
ANO6 anoctamin 6 0.0342355
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0341035
PTPN14 protein tyrosine phosphatase, non-receptor type 14 0.0338203
YAP1 Yes-associated protein 1 0.032801
HSPA8 heat shock 70kDa protein 8 0.0324978
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0320995
CD46 CD46 molecule, complement regulatory protein 0.0318448
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 0.0316333
ZNF292 zinc finger protein 292 0.0316058
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1 0.0315613
CMIP c-Maf inducing protein 0.0310364
RUNX1 runt-related transcription factor 1 0.0307978
TRIO trio Rho guanine nucleotide exchange factor 0.0304987
PRELID2 PRELI domain containing 2 0.0297666
SFPQ splicing factor proline/glutamine-rich 0.029225
ETNK1 ethanolamine kinase 1 0.0286274
RICTOR RPTOR independent companion of MTOR, complex 2 0.0286258
RNF43 ring finger protein 43 0.0283049
EIF4B eukaryotic translation initiation factor 4B 0.0282197
MSN moesin 0.0280521
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 0.0278305
RPL3 ribosomal protein L3 0.0277497
BHLHE40 basic helix-loop-helix family, member e40 0.0277439
MINK1 misshapen-like kinase 1 0.0276069
RAD51B RAD51 paralog B 0.0275073
EFNB2 ephrin-B2 0.0274495
SBF2 SET binding factor 2 0.0272584
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0272086
CTNND1 catenin (cadherin-associated protein), delta 1 0.0271654
ZNRF3 zinc and ring finger 3 0.0271439
NUMA1 nuclear mitotic apparatus protein 1 0.0265472
PKM pyruvate kinase, muscle 0.0263992
LMO7 LIM domain 7 0.0261398
KMT2C lysine (K)-specific methyltransferase 2C 0.0260101
PRPF8 pre-mRNA processing factor 8 0.0258953
LENG8 leukocyte receptor cluster (LRC) member 8 0.0256053
LPP LIM domain containing preferred translocation partner in lipoma 0.0255672
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0253073
LOC112694756 uncharaterized LOC112694756 0.0252388
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.0248581
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 0.0247508
ARHGAP32 Rho GTPase activating protein 32 0.0247082
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.024152
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0240224
DSCAM Down syndrome cell adhesion molecule 0.0239908
SRRM2 serine/arginine repetitive matrix 2 0.0236822
MAN1A1 mannosidase, alpha, class 1A, member 1 0.0232251
MED13 mediator complex subunit 13 0.0232151
PGK1 phosphoglycerate kinase 1 0.0231806
BRWD3 bromodomain and WD repeat domain containing 3 0.0227723
PCM1 pericentriolar material 1 0.022714
YEATS2 YEATS domain containing 2 0.0226996
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0226974
WDFY2 WD repeat and FYVE domain containing 2 0.0226914

decreased expression

Symbol Name Standardized Value
AKAP12 A kinase (PRKA) anchor protein 12 -0.0733796
TMSB10 thymosin beta 10 -0.0688017
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0510173
CCND1 cyclin D1 -0.0414376
CDK6 cyclin-dependent kinase 6 -0.0359866
LOC102724023 ES1 protein homolog, mitochondrial -0.0352901
RPS3 ribosomal protein S3 -0.0343206
PTMA prothymosin, alpha -0.0339363
IARS1 isoleucyl-tRNA synthetase 1 -0.0335153
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0318457
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0315778
RBM25 RNA binding motif protein 25 -0.0314629
CDH13 cadherin 13 -0.0302324
GARS1 glycyl-tRNA synthetase 1 -0.02725
EIF1 eukaryotic translation initiation factor 1 -0.0267513
RPS6 ribosomal protein S6 -0.0251812
TPM4 tropomyosin 4 -0.0206747
SLC38A1 solute carrier family 38, member 1 -0.0204519
VCL vinculin -0.0201485
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0197896
RPS24 ribosomal protein S24 -0.019369
MT2A metallothionein 2A -0.0193552
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 -0.0192525
EIF5B eukaryotic translation initiation factor 5B -0.0190987
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0190746
VIM vimentin -0.0190026
RPL35A ribosomal protein L35a -0.0189743
PERP PERP, TP53 apoptosis effector -0.0189551
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0188636
RPL32 ribosomal protein L32 -0.0184991
RPS27A ribosomal protein S27a -0.0182341
ACTG1 actin gamma 1 -0.0182127
DOCK9 dedicator of cytokinesis 9 -0.0181984
DUSP6 dual specificity phosphatase 6 -0.0180096
RPL31 ribosomal protein L31 -0.0179537
LARS1 leucyl-tRNA synthetase 1 -0.01772
TPT1 tumor protein, translationally-controlled 1 -0.0176718
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 -0.0173788
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0173681
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0167962
ARF4 ADP-ribosylation factor 4 -0.0167886
RPL19 ribosomal protein L19 -0.0165387
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0165151
CANX calnexin -0.0164955
RPL12 ribosomal protein L12 -0.0164146
RPLP2 ribosomal protein, large, P2 -0.0162558
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0160038
FTL ferritin, light polypeptide -0.0159381
RPS11 ribosomal protein S11 -0.0153661
RPLP1 ribosomal protein, large, P1 -0.0150083
RPS13 ribosomal protein S13 -0.0148853
DMGDH dimethylglycine dehydrogenase -0.0148515
THOC2 THO complex 2 -0.014841
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0148095
RPS19 ribosomal protein S19 -0.0147903
MT1X metallothionein 1X -0.0147874
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -0.0146198
HP1BP3 heterochromatin protein 1, binding protein 3 -0.0145397
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0144881
RPL18 ribosomal protein L18 -0.0144507
IER3 immediate early response 3 -0.0140241
RPS21 ribosomal protein S21 -0.0139857
RSL1D1 ribosomal L1 domain containing 1 -0.0139174
RHOBTB3 Rho-related BTB domain containing 3 -0.0138009
MYL12B myosin, light chain 12B, regulatory -0.0137427
GCC2 GRIP and coiled-coil domain containing 2 -0.0137193
GCLC glutamate-cysteine ligase, catalytic subunit -0.0137188
ATF4 activating transcription factor 4 -0.0136848
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -0.0136537
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -0.0134442
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0132594
SOX4 SRY (sex determining region Y)-box 4 -0.0131531
DSTN destrin (actin depolymerizing factor) -0.0131189
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0130293
KPNB1 karyopherin (importin) beta 1 -0.0129271
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric -0.0129219
PDE4D phosphodiesterase 4D, cAMP-specific -0.0129063
RPL27A ribosomal protein L27a -0.0127275
CDK13 cyclin-dependent kinase 13 -0.0126291
CLDN1 claudin 1 -0.0125921
S100A6 S100 calcium binding protein A6 -0.0125049
LIMS1 LIM and senescent cell antigen-like domains 1 -0.0123043
SKAP1 src kinase associated phosphoprotein 1 -0.0121635
SYT1 synaptotagmin I -0.0121613
RPS5 ribosomal protein S5 -0.0121586
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.0121234
S100A11 S100 calcium binding protein A11 -0.0121197
PFN1 profilin 1 -0.0120783
ATRX alpha thalassemia/mental retardation syndrome X-linked -0.0120233
RPL8 ribosomal protein L8 -0.0119976
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -0.0119781
AIG1 androgen-induced 1 -0.0118899
RPL36 ribosomal protein L36 -0.0118321
UBB ubiquitin B -0.0117008
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -0.0116859
COL8A1 collagen, type VIII, alpha 1 -0.0115868
RPL34 ribosomal protein L34 -0.0115289
RPL11 ribosomal protein L11 -0.0114904
SMCO2 single-pass membrane protein with coiled-coil domains 2 -0.011469
RPS29 ribosomal protein S29 -0.0114664