Fibromyalgia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A chronic disorder of unknown etiology characterized by pain, stiffness, and tenderness in the muscles of neck, shoulders, back, hips, arms, and legs. Other signs and symptoms include headaches, fatigue, sleep disturbances, and painful menstruation. (Experimental Factor Ontology, EFO_0005687)
External Link https://www.disgenet.org/browser/0/1/0/C0016053
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Genes

134 genes associated with the disease Fibromyalgia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACE angiotensin I converting enzyme
ACR acrosin
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRB2 adrenoceptor beta 2, surface
ADRM1 adhesion regulating molecule 1
ALB albumin
ANPEP alanyl (membrane) aminopeptidase
APOC1 apolipoprotein C-I
APOE apolipoprotein E
ASIC3 acid sensing (proton gated) ion channel 3
BDNF brain-derived neurotrophic factor
CASP1 caspase 1, apoptosis-related cysteine peptidase
CAT catalase
CCL11 chemokine (C-C motif) ligand 11
CCL2 chemokine (C-C motif) ligand 2
CCL24 chemokine (C-C motif) ligand 24
CCL4 chemokine (C-C motif) ligand 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CES2 carboxylesterase 2
CHRM3 cholinergic receptor, muscarinic 3
CNTN3 contactin 3 (plasmacytoma associated)
COMT catechol-O-methyltransferase
CPQ carboxypeptidase Q
CRH corticotropin releasing hormone
CRP C-reactive protein, pentraxin-related
CRYGD crystallin, gamma D
CSF1R colony stimulating factor 1 receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CXCL8 chemokine (C-X-C motif) ligand 8
DOCK11 dedicator of cytokinesis 11
DRD3 dopamine receptor D3
EDN1 endothelin 1
EFNA4 ephrin-A4
EMB embigin
ENO1 enolase 1, (alpha)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHA4 EPH receptor A4
ESR1 estrogen receptor 1
F2 coagulation factor II (thrombin)
FAS Fas cell surface death receptor
FES FES proto-oncogene, tyrosine kinase
FMR1 fragile X mental retardation 1
GCH1 GTP cyclohydrolase 1
GH1 growth hormone 1
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GPX1 glutathione peroxidase 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GSR glutathione reductase
HFE hemochromatosis
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HP haptoglobin
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFALS insulin-like growth factor binding protein, acid labile subunit
IL10 interleukin 10
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL37 interleukin 37
IL4 interleukin 4
IL6 interleukin 6
KLK4 kallikrein-related peptidase 4
KRT7 keratin 7, type II
L1CAM L1 cell adhesion molecule
LAMC2 laminin, gamma 2
LEP leptin
LNPEP leucyl/cystinyl aminopeptidase
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MAPK8 mitogen-activated protein kinase 8
MEFV Mediterranean fever
MFN2 mitofusin 2
MOS v-mos Moloney murine sarcoma viral oncogene homolog
MT-CYB cytochrome b
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYT1L myelin transcription factor 1-like
NGF nerve growth factor (beta polypeptide)
NLRP3 NLR family, pyrin domain containing 3
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPS neuropeptide S
NPY neuropeptide Y
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRXN3 neurexin 3
OPRD1 opioid receptor, delta 1
OPRL1 opiate receptor-like 1
OPRM1 opioid receptor, mu 1
PCLAF PCNA clamp associated factor
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PNOC prepronociceptin
POMC proopiomelanocortin
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PSIP1 PC4 and SFRS1 interacting protein 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
SCG2 secretogranin II
SCLY selenocysteine lyase
SCN9A sodium channel, voltage gated, type IX alpha subunit
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SNAP25 synaptosomal-associated protein, 25kDa
SOD1 superoxide dismutase 1, soluble
TAC1 tachykinin, precursor 1
TAC4 tachykinin 4 (hemokinin)
TACR1 tachykinin receptor 1
TAL1 T-cell acute lymphocytic leukemia 1
TCP1 t-complex 1
TF transferrin
TNF tumor necrosis factor
TP53INP2 tumor protein p53 inducible nuclear protein 2
TPO thyroid peroxidase
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TSC22D3 TSC22 domain family, member 3
TSHR thyroid stimulating hormone receptor
TSPO translocator protein (18kDa)
TTN titin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
ZNF77 zinc finger protein 77