Fibrosarcoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0016057
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Genes

399 genes associated with the disease Fibrosarcoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACE angiotensin I converting enzyme
ACTB actin, beta
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADGRE2 adhesion G protein-coupled receptor E2
ADGRE5 adhesion G protein-coupled receptor E5
AGER advanced glycosylation end product-specific receptor
AHI1 Abelson helper integration site 1
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKAP12 A kinase (PRKA) anchor protein 12
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALPK1 alpha-kinase 1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPT4 angiopoietin 4
ANGPTL1 angiopoietin-like 1
ANPEP alanyl (membrane) aminopeptidase
ANXA3 annexin A3
ANXA5 annexin A5
APRT adenine phosphoribosyltransferase
ARF6 ADP-ribosylation factor 6
ARFIP1 ADP-ribosylation factor interacting protein 1
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARL4C ADP-ribosylation factor-like 4C
ASCC1 activating signal cointegrator 1 complex subunit 1
ATF4 activating transcription factor 4
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BGN biglycan
BRAF B-Raf proto-oncogene, serine/threonine kinase
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCN2 cellular communication network factor 2
CCND1 cyclin D1
CD226 CD226 molecule
CD274 CD274 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CDC123 cell division cycle 123
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CER1 cerberus 1, DAN family BMP antagonist
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CLDN2 claudin 2
CLU clusterin
CMA1 chymase 1, mast cell
CNBP CCHC-type zinc finger, nucleic acid binding protein
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CPE carboxypeptidase E
CREB3L1 cAMP responsive element binding protein 3-like 1
CREB3L2 cAMP responsive element binding protein 3-like 2
CREG1 cellular repressor of E1A-stimulated genes 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSF1R colony stimulating factor 1 receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CST3 cystatin C
CTAG1A cancer/testis antigen 1A
CTAG1B cancer/testis antigen 1B
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUX1 cut-like homeobox 1
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT3 DNA-damage-inducible transcript 3
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DLD dihydrolipoamide dehydrogenase
DPYD dihydropyrimidine dehydrogenase
DPYS dihydropyrimidinase
E2F1 E2F transcription factor 1
EBP emopamil binding protein (sterol isomerase)
EGFR epidermal growth factor receptor
EGR1 early growth response 1
ELK1 ELK1, member of ETS oncogene family
EPHA3 EPH receptor A3
EPHB2 EPH receptor B2
EPHB4 EPH receptor B4
ERBB2 erb-b2 receptor tyrosine kinase 2
ETV4 ets variant 4
ETV6 ets variant 6
EWSR1 EWS RNA-binding protein 1
F3 coagulation factor III (thromboplastin, tissue factor)
FADD Fas (TNFRSF6)-associated via death domain
FBLN1 fibulin 1
FBXW11 F-box and WD repeat domain containing 11
FGF1 fibroblast growth factor 1 (acidic)
FGF2 fibroblast growth factor 2 (basic)
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLNA filamin A, alpha
FLT1 fms-related tyrosine kinase 1
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXC2 forkhead box C2
FOXP3 forkhead box P3
FUS FUS RNA binding protein
GAL galanin/GMAP prepropeptide
GCG glucagon
GDF10 growth differentiation factor 10
GFAP glial fibrillary acidic protein
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GJA1 gap junction protein, alpha 1, 43kDa
GLB1 galactosidase, beta 1
GLIS3 GLIS family zinc finger 3
GLO1 glyoxalase I
GORASP1 golgi reassembly stacking protein 1, 65kDa
GP6 glycoprotein VI (platelet)
GPI glucose-6-phosphate isomerase
GPX4 glutathione peroxidase 4
GRAP2 GRB2-related adaptor protein 2
GSK3B glycogen synthase kinase 3 beta
GSTK1 glutathione S-transferase kappa 1
HCCS holocytochrome c synthase
HCLS1 hematopoietic cell-specific Lyn substrate 1
HDAC1 histone deacetylase 1
HDAC9 histone deacetylase 9
HEATR3 HEAT repeat containing 3
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HK1 hexokinase 1
HLA-C major histocompatibility complex, class I, C
HMGA2 high mobility group AT-hook 2
HPRT1 hypoxanthine phosphoribosyltransferase 1
HPSE heparanase
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA14 heat shock 70kDa protein 14
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HSPA4 heat shock 70kDa protein 4
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPB1 heat shock 27kDa protein 1
HSPB2 heat shock 27kDa protein 2
HSPB3 heat shock 27kDa protein 3
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPG2 heparan sulfate proteoglycan 2
ICAM1 intercellular adhesion molecule 1
ICK intestinal cell (MAK-like) kinase
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IL10 interleukin 10
IL15 interleukin 15
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL2 interleukin 2
IL2RB interleukin 2 receptor, beta
IL6 interleukin 6
INSL6 insulin-like 6
IRF9 interferon regulatory factor 9
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAG1 jagged 1
JAK1 Janus kinase 1
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8
KDR kinase insert domain receptor
KHSRP KH-type splicing regulatory protein
KIF5B kinesin family member 5B
KITLG KIT ligand
KLRC4-KLRK1 KLRC4-KLRK1 readthrough
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2A lysine (K)-specific methyltransferase 2A
LAG3 lymphocyte-activation gene 3
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LDLR low density lipoprotein receptor
LIMK2 LIM domain kinase 2
LPA lipoprotein, Lp(a)
LPAR2 lysophosphatidic acid receptor 2
LPAR5 lysophosphatidic acid receptor 5
LRIF1 ligand dependent nuclear receptor interacting factor 1
LRP6 low density lipoprotein receptor-related protein 6
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K20 mitogen-activated protein kinase kinase kinase 20
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MAU2 MAU2 sister chromatid cohesion factor
MCRS1 microspherule protein 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MET MET proto-oncogene, receptor tyrosine kinase
MFAP1 microfibrillar-associated protein 1
MIA melanoma inhibitory activity
MIB1 mindbomb E3 ubiquitin protein ligase 1
MINK1 misshapen-like kinase 1
MKI67 marker of proliferation Ki-67
MLANA melan-A
MLKL mixed lineage kinase domain-like
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP25 matrix metallopeptidase 25
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MNS1 meiosis-specific nuclear structural 1
MSH2 mutS homolog 2
MTAP methylthioadenosine phosphorylase
MTF1 metal-regulatory transcription factor 1
MUC4 mucin 4, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAMPT nicotinamide phosphoribosyltransferase
NCKIPSD NCK interacting protein with SH3 domain
NCOA7 nuclear receptor coactivator 7
NES nestin
NEUROD1 neuronal differentiation 1
NF1 neurofibromin 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
NME2 NME/NM23 nucleoside diphosphate kinase 2
NR2E1 nuclear receptor subfamily 2, group E, member 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
ODC1 ornithine decarboxylase 1
PAEP progestagen-associated endometrial protein
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAM peptidylglycine alpha-amidating monooxygenase
PARP1 poly (ADP-ribose) polymerase 1
PC pyruvate carboxylase
PCLAF PCNA clamp associated factor
PDGFB platelet-derived growth factor beta polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDLIM5 PDZ and LIM domain 5
PDX1 pancreatic and duodenal homeobox 1
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase
PGF placental growth factor
PGPEP1 pyroglutamyl-peptidase I
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLG plasminogen
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POTEF POTE ankyrin domain family, member F
POU5F1 POU class 5 homeobox 1
PRDM1 PR domain containing 1, with ZNF domain
PRDX1 peroxiredoxin 1
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PROM1 prominin 1
PRRT2 proline-rich transmembrane protein 2
PSAP prosaposin
PSIP1 PC4 and SFRS1 interacting protein 1
PTEN phosphatase and tensin homolog
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTK7 protein tyrosine kinase 7 (inactive)
PTX3 pentraxin 3, long
PVR poliovirus receptor
PXN paxillin
PYCARD PYD and CARD domain containing
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAD17 RAD17 homolog (S. pombe)
RAD51 RAD51 recombinase
RAD51B RAD51 paralog B
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALBP1 ralA binding protein 1
RAP1A RAP1A, member of RAS oncogene family
RBM5 RNA binding motif protein 5
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RET ret proto-oncogene
REV1 REV1, polymerase (DNA directed)
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIF1 replication timing regulatory factor 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK3 receptor-interacting serine-threonine kinase 3
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNMT RNA (guanine-7-) methyltransferase
ROR1 receptor tyrosine kinase-like orphan receptor 1
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RRAS related RAS viral (r-ras) oncogene homolog
RRM2 ribonucleotide reductase M2
RSPO2 R-spondin 2
RTL1 retrotransposon-like 1
SDC1 syndecan 1
SDC2 syndecan 2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SETD2 SET domain containing 2
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC12A9 solute carrier family 12, member 9
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC39A13 solute carrier family 39 (zinc transporter), member 13
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SLFN5 schlafen family member 5
SLTM SAFB-like, transcription modulator
SMAD2 SMAD family member 2
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMYD3 SET and MYND domain containing 3
SNRPE small nuclear ribonucleoprotein polypeptide E
SOX2 SRY (sex determining region Y)-box 2
SOX21 SRY (sex determining region Y)-box 21
SP1 Sp1 transcription factor
SPRY2 sprouty homolog 2 (Drosophila)
SPZ1 spermatogenic leucine zipper 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STK3 serine/threonine kinase 3
STS steroid sulfatase (microsomal), isozyme S
SYN1 synapsin I
SYT1 synaptotagmin I
TAT tyrosine aminotransferase
TAZ tafazzin
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBPL1 TBP-like 1
TBX3 T-box 3
TBX5 T-box 5
TCF3 transcription factor 3
TCL1B T-cell leukemia/lymphoma 1B
TEK TEK tyrosine kinase, endothelial
TERF2 telomeric repeat binding factor 2
TERT telomerase reverse transcriptase
TFPI2 tissue factor pathway inhibitor 2
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMSB4X thymosin beta 4, X-linked
TNC tenascin C
TNF tumor necrosis factor
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TOP1 topoisomerase (DNA) I
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP63 tumor protein p63
TPSAB1 tryptase alpha/beta 1
TPT1 tumor protein, translationally-controlled 1
TRAF2 TNF receptor-associated factor 2
TRIM59 tripartite motif containing 59
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTL tubulin tyrosine ligase
TTLL1 tubulin tyrosine ligase-like family member 1
TXN thioredoxin
TYK2 tyrosine kinase 2
UCN urocortin
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae)
VTN vitronectin
WFDC1 WAP four-disulfide core domain 1
WNK1 WNK lysine deficient protein kinase 1
WWOX WW domain containing oxidoreductase
XPA xeroderma pigmentosum, complementation group A
ZFP57 ZFP57 zinc finger protein
ZHX2 zinc fingers and homeoboxes 2
ZNF398 zinc finger protein 398