| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Filgotinib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Filgotinib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA6 | integrin, alpha 6 | 0.128947 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.114714 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.109304 |
| SPATA13 | spermatogenesis associated 13 | 0.107308 |
| MACC1 | metastasis associated in colon cancer 1 | 0.106653 |
| RUNX1 | runt-related transcription factor 1 | 0.099752 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0995146 |
| ABHD2 | abhydrolase domain containing 2 | 0.0852508 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0852225 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0826913 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0794689 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0719794 |
| NCKAP5 | NCK-associated protein 5 | 0.067935 |
| RNF43 | ring finger protein 43 | 0.0631154 |
| DSPP | dentin sialophosphoprotein | 0.0623561 |
| PHF3 | PHD finger protein 3 | 0.0618622 |
| MYO1E | myosin IE | 0.0615146 |
| SERINC5 | serine incorporator 5 | 0.0603991 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0596663 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0555268 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0554859 |
| STK24 | serine/threonine kinase 24 | 0.0551084 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0550746 |
| B2M | beta-2-microglobulin | 0.0547015 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.054179 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0537476 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0537276 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0526832 |
| USP54 | ubiquitin specific peptidase 54 | 0.0509289 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0494948 |
| H1-0 | H1.0 linker histone | 0.0490913 |
| TXNIP | thioredoxin interacting protein | 0.0487179 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.048714 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0482788 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0472789 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.047188 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0470033 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0468472 |
| ETNK1 | ethanolamine kinase 1 | 0.046632 |
| EPHB2 | EPH receptor B2 | 0.0451046 |
| ADD3 | adducin 3 (gamma) | 0.0444679 |
| YAP1 | Yes-associated protein 1 | 0.0442341 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0429923 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0428753 |
| TMEM62 | transmembrane protein 62 | 0.0426081 |
| FOXP1 | forkhead box P1 | 0.0420285 |
| APP | amyloid beta (A4) precursor protein | 0.0412806 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0412036 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0410478 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0406351 |
| MEIS2 | Meis homeobox 2 | 0.0402926 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0400469 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0395256 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0392815 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.039075 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0383445 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0382094 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0378958 |
| BCL2L1 | BCL2-like 1 | 0.0375121 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0372986 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0366293 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0365576 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0364084 |
| ERBIN | erbb2 interacting protein | 0.036048 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.035753 |
| MECOM | MDS1 and EVI1 complex locus | 0.0357155 |
| PRSS3 | protease, serine, 3 | 0.0356335 |
| ETV6 | ets variant 6 | 0.0354909 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.035481 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0353965 |
| LIMA1 | LIM domain and actin binding 1 | 0.0348895 |
| AOPEP | aminopeptidase O (putative) | 0.0343781 |
| MSI2 | musashi RNA-binding protein 2 | 0.0338515 |
| TMC5 | transmembrane channel-like 5 | 0.0337752 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0336811 |
| FAT1 | FAT atypical cadherin 1 | 0.0336494 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0334011 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0332694 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0332519 |
| ABLIM1 | actin binding LIM protein 1 | 0.0331645 |
| EHF | ets homologous factor | 0.0331125 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0329698 |
| PGK1 | phosphoglycerate kinase 1 | 0.0329069 |
| TJP2 | tight junction protein 2 | 0.0328159 |
| ANXA4 | annexin A4 | 0.0326638 |
| IL20RA | interleukin 20 receptor, alpha | 0.0323199 |
| ANXA11 | annexin A11 | 0.0322986 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0322245 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.03221 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0322019 |
| VCL | vinculin | 0.0321134 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.031899 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0318165 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | 0.0314331 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0312526 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0307693 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0305907 |
| NEBL | nebulette | 0.0302279 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0298992 |
| FMN1 | formin 1 | 0.0297154 |
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | -0.159394 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0949162 |
| PLSCR2 | phospholipid scramblase 2 | -0.080683 |
| RNF213 | ring finger protein 213 | -0.0713366 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0590682 |
| LCN2 | lipocalin 2 | -0.0569956 |
| SQSTM1 | sequestosome 1 | -0.0553511 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0535927 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0496494 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0479373 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0476786 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0431166 |
| RPS6 | ribosomal protein S6 | -0.042293 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0419129 |
| EGR1 | early growth response 1 | -0.0396351 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0386806 |
| RIGI | RNA sensor RIG-I | -0.0372037 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0336948 |
| NDRG1 | N-myc downstream regulated 1 | -0.0336123 |
| NABP1 | nucleic acid binding protein 1 | -0.0333415 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0302915 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0299899 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0275927 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0267793 |
| RPL23 | ribosomal protein L23 | -0.0266829 |
| RPL35A | ribosomal protein L35a | -0.0259465 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.025196 |
| RPL37A | ribosomal protein L37a | -0.0245448 |
| MORF4L2 | mortality factor 4 like 2 | -0.0243955 |
| RPL12 | ribosomal protein L12 | -0.0242491 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0235471 |
| HM13 | histocompatibility (minor) 13 | -0.0228057 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0219166 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0215989 |
| FTL | ferritin, light polypeptide | -0.0213473 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0208347 |
| SDCBP | syndecan binding protein (syntenin) | -0.020768 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0204692 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0203245 |
| RPS8 | ribosomal protein S8 | -0.0201501 |
| RPL19 | ribosomal protein L19 | -0.0200851 |
| HOMER1 | homer scaffolding protein 1 | -0.0198172 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0197371 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0197062 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0195932 |
| GK | glycerol kinase | -0.0193652 |
| IRF1 | interferon regulatory factor 1 | -0.0193357 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0192839 |
| AHI1 | Abelson helper integration site 1 | -0.0192601 |
| PMM2 | phosphomannomutase 2 | -0.019138 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0191306 |
| RPS12 | ribosomal protein S12 | -0.0190583 |
| RPL28 | ribosomal protein L28 | -0.0186142 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.018534 |
| RPLP2 | ribosomal protein, large, P2 | -0.0184021 |
| ANXA1 | annexin A1 | -0.0183348 |
| RPL31 | ribosomal protein L31 | -0.0182893 |
| TLE4 | transducin-like enhancer of split 4 | -0.0181219 |
| FUS | FUS RNA binding protein | -0.0181057 |
| RPL34 | ribosomal protein L34 | -0.0178712 |
| FBXO39 | F-box protein 39 | -0.0175937 |
| RPS17 | ribosomal protein S17 | -0.0173703 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0172886 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.017121 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0170441 |
| TOP1 | topoisomerase (DNA) I | -0.0170135 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0169346 |
| RPLP1 | ribosomal protein, large, P1 | -0.0168773 |
| GOLGA4 | golgin A4 | -0.0168293 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0167425 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0166453 |
| UBAP2 | ubiquitin associated protein 2 | -0.0166233 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0166226 |
| RPS27A | ribosomal protein S27a | -0.0163269 |
| ADM | adrenomedullin | -0.0162192 |
| RPL8 | ribosomal protein L8 | -0.0162038 |
| GOSR2 | golgi SNAP receptor complex member 2 | -0.0161925 |
| CALU | calumenin | -0.0161748 |
| TMSB10 | thymosin beta 10 | -0.0161693 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0161653 |
| KYNU | kynureninase | -0.0161434 |
| RPS19 | ribosomal protein S19 | -0.0160301 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0159058 |
| RPL26 | ribosomal protein L26 | -0.0157184 |
| RPL13A | ribosomal protein L13a | -0.0157113 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0155694 |
| RPL9 | ribosomal protein L9 | -0.0154865 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0154736 |
| AREG | amphiregulin | -0.0152983 |
| ATF4 | activating transcription factor 4 | -0.0152211 |
| DUSP10 | dual specificity phosphatase 10 | -0.0148714 |
| RPS20 | ribosomal protein S20 | -0.014709 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0145377 |
| RPS3 | ribosomal protein S3 | -0.0145243 |
| S100A9 | S100 calcium binding protein A9 | -0.0142401 |
| RPS25 | ribosomal protein S25 | -0.0140719 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.014049 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0137442 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0136558 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0136319 |
