| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Filgotinib perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Filgotinib_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FOXO1 | forkhead box O1 | 0.101879 |
| PDLIM5 | PDZ and LIM domain 5 | 0.100761 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0991242 |
| BLCAP | bladder cancer associated protein | 0.0979755 |
| VCL | vinculin | 0.087344 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0869471 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0762816 |
| NRG1 | neuregulin 1 | 0.0755558 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0681142 |
| MECOM | MDS1 and EVI1 complex locus | 0.0680954 |
| ITGA6 | integrin, alpha 6 | 0.0652777 |
| AOPEP | aminopeptidase O (putative) | 0.0638829 |
| DST | dystonin | 0.0602957 |
| NEK7 | NIMA-related kinase 7 | 0.0595341 |
| PALLD | palladin, cytoskeletal associated protein | 0.0594637 |
| MYOF | myoferlin | 0.0534657 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0530679 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.051921 |
| ANKRD33B | ankyrin repeat domain 33B | 0.051408 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0492586 |
| RBM39 | RNA binding motif protein 39 | 0.0491409 |
| FOXP1 | forkhead box P1 | 0.0476584 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0437214 |
| EXOC6B | exocyst complex component 6B | 0.0430747 |
| SULF1 | sulfatase 1 | 0.0427011 |
| HDAC9 | histone deacetylase 9 | 0.0418723 |
| FAT1 | FAT atypical cadherin 1 | 0.0399462 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0399202 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0383239 |
| PRELID2 | PRELI domain containing 2 | 0.0373814 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0365534 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0354961 |
| CAPRIN2 | caprin family member 2 | 0.0346452 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0346303 |
| FLNA | filamin A, alpha | 0.0344504 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0340828 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0337696 |
| AHNAK | AHNAK nucleoprotein | 0.0337372 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0335835 |
| TSC22D1 | TSC22 domain family, member 1 | 0.033023 |
| MEF2C | myocyte enhancer factor 2C | 0.0327915 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0327718 |
| FAM107B | family with sequence similarity 107, member B | 0.032342 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0319721 |
| ASPH | aspartate beta-hydroxylase | 0.0315228 |
| GOLGB1 | golgin B1 | 0.029021 |
| HMGA2 | high mobility group AT-hook 2 | 0.0287863 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0285241 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0285094 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0280952 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.027738 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.027483 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.026966 |
| AFAP1L2 | actin filament associated protein 1-like 2 | 0.0262612 |
| ZNF292 | zinc finger protein 292 | 0.026254 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0259041 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0254363 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0254126 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.025159 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0250006 |
| TXNRD1 | thioredoxin reductase 1 | 0.0248005 |
| SMAD3 | SMAD family member 3 | 0.0247394 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0247281 |
| LMO7 | LIM domain 7 | 0.0244231 |
| NBEA | neurobeachin | 0.0243472 |
| SMYD3 | SET and MYND domain containing 3 | 0.0238088 |
| METTL15 | methyltransferase like 15 | 0.0232426 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.022975 |
| BCL2L1 | BCL2-like 1 | 0.0227556 |
| MSN | moesin | 0.022673 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0223856 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0222135 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0219976 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.021736 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0214685 |
| TNS3 | tensin 3 | 0.0208812 |
| FLOT1 | flotillin 1 | 0.0207974 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0207641 |
| RBM25 | RNA binding motif protein 25 | 0.0206681 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.020634 |
| CD44 | CD44 molecule (Indian blood group) | 0.0204926 |
| MYO10 | myosin X | 0.0203598 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0201845 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.0200697 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0197024 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0196535 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0194997 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0194969 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0193668 |
| TPM3 | tropomyosin 3 | 0.0192843 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0192631 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0191191 |
| PLEC | plectin | 0.0188473 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0187569 |
| SH3D19 | SH3 domain containing 19 | 0.0187093 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0186659 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0184619 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0184084 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0183717 |
| TJP1 | tight junction protein 1 | 0.0181378 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | -0.172802 |
| NDRG1 | N-myc downstream regulated 1 | -0.1648 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.13009 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.130084 |
| MT2A | metallothionein 2A | -0.113898 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.103593 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.102852 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0984311 |
| TMSB10 | thymosin beta 10 | -0.0984184 |
| HLA-B | major histocompatibility complex, class I, B | -0.0958427 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.09461 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0892935 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0842548 |
| TMSB4X | thymosin beta 4, X-linked | -0.0777579 |
| RPS21 | ribosomal protein S21 | -0.0765189 |
| MTSS1 | metastasis suppressor 1 | -0.0747643 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0745308 |
| STC1 | stanniocalcin 1 | -0.0743622 |
| IFI44L | interferon-induced protein 44-like | -0.0693598 |
| PTMA | prothymosin, alpha | -0.0674621 |
| S100A10 | S100 calcium binding protein A10 | -0.0660579 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0629502 |
| HLA-E | major histocompatibility complex, class I, E | -0.0620808 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0620468 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0610873 |
| SP100 | SP100 nuclear antigen | -0.0599198 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0586615 |
| RIGI | RNA sensor RIG-I | -0.0582572 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0581735 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0577294 |
| IFI44 | interferon-induced protein 44 | -0.0562322 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0555505 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.052789 |
| S100A9 | S100 calcium binding protein A9 | -0.0514715 |
| IGF2 | insulin-like growth factor 2 | -0.0514646 |
| S100A11 | S100 calcium binding protein A11 | -0.0495016 |
| FTL | ferritin, light polypeptide | -0.0486381 |
| NAV2 | neuron navigator 2 | -0.0485083 |
| RPLP2 | ribosomal protein, large, P2 | -0.0484657 |
| FLNB | filamin B, beta | -0.0484399 |
| RPLP1 | ribosomal protein, large, P1 | -0.047592 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0471981 |
| RAI14 | retinoic acid induced 14 | -0.046169 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0452887 |
| H1-0 | H1.0 linker histone | -0.0446726 |
| RPS19 | ribosomal protein S19 | -0.0441119 |
| MX1 | MX dynamin-like GTPase 1 | -0.0437436 |
| TGM2 | transglutaminase 2 | -0.0433835 |
| LAMC2 | laminin, gamma 2 | -0.0431936 |
| ADAR | adenosine deaminase, RNA-specific | -0.0425531 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0424286 |
| TXNIP | thioredoxin interacting protein | -0.042424 |
| MT1X | metallothionein 1X | -0.0421833 |
| HLA-A | major histocompatibility complex, class I, A | -0.0421576 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0411585 |
| ENO1 | enolase 1, (alpha) | -0.0407329 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0401448 |
| S100A6 | S100 calcium binding protein A6 | -0.0394694 |
| POTEF | POTE ankyrin domain family, member F | -0.0385738 |
| RPS13 | ribosomal protein S13 | -0.0383735 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0379764 |
| RPS8 | ribosomal protein S8 | -0.0377945 |
| DSG2 | desmoglein 2 | -0.0377433 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0376603 |
| RPL12 | ribosomal protein L12 | -0.0376501 |
| TPM4 | tropomyosin 4 | -0.0373221 |
| CSTB | cystatin B (stefin B) | -0.0362407 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0359207 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.034967 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0349665 |
| UBC | ubiquitin C | -0.0349338 |
| PODXL | podocalyxin-like | -0.0342992 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0341377 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0337649 |
| RPS24 | ribosomal protein S24 | -0.0336786 |
| SULF2 | sulfatase 2 | -0.0334911 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0332623 |
| KISS1 | KiSS-1 metastasis-suppressor | -0.0330638 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0326257 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0325295 |
| RPS6 | ribosomal protein S6 | -0.0321346 |
| MX2 | MX dynamin-like GTPase 2 | -0.0319126 |
| RPL35A | ribosomal protein L35a | -0.0318378 |
| PGK1 | phosphoglycerate kinase 1 | -0.0316827 |
| LDHA | lactate dehydrogenase A | -0.0309064 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0308111 |
| RPL37 | ribosomal protein L37 | -0.0306245 |
| CDCP1 | CUB domain containing protein 1 | -0.0299152 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0298952 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0297648 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0297215 |
| PMP22 | peripheral myelin protein 22 | -0.0297155 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.0295122 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0295005 |
| KRT17 | keratin 17, type I | -0.029288 |
| GNAS | GNAS complex locus | -0.029241 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0290862 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0289831 |
| ANXA1 | annexin A1 | -0.0289164 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.0288437 |
