| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Filgotinib perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Filgotinib_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | 0.153226 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.152179 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.150511 |
| FN1 | fibronectin 1 | 0.147098 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.137603 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.12821 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.118696 |
| VCL | vinculin | 0.0813922 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0773744 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0743211 |
| PDE10A | phosphodiesterase 10A | 0.0739187 |
| NAV2 | neuron navigator 2 | 0.0724556 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0627152 |
| JMJD1C | jumonji domain containing 1C | 0.0610581 |
| MYOF | myoferlin | 0.0605723 |
| SEPTIN9 | septin 9 | 0.0580805 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0568594 |
| CADM1 | cell adhesion molecule 1 | 0.0558811 |
| PRELID2 | PRELI domain containing 2 | 0.0553742 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0549642 |
| FNIP1 | folliculin interacting protein 1 | 0.0543989 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0532065 |
| HMGA2 | high mobility group AT-hook 2 | 0.0522408 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0510685 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0508753 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.050834 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0501628 |
| TNS3 | tensin 3 | 0.0495046 |
| NAV1 | neuron navigator 1 | 0.0450459 |
| ATXN1 | ataxin 1 | 0.0448778 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0446489 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0416887 |
| RAD51B | RAD51 paralog B | 0.0415126 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0403184 |
| AHNAK | AHNAK nucleoprotein | 0.0401183 |
| PHF3 | PHD finger protein 3 | 0.0397233 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0395212 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0392166 |
| FLNA | filamin A, alpha | 0.0388357 |
| MSN | moesin | 0.0388009 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.038578 |
| SYNJ2 | synaptojanin 2 | 0.0381074 |
| OGA | O-GlcNAcase | 0.0374758 |
| DST | dystonin | 0.0371517 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0367396 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0367134 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0366427 |
| MCL1 | myeloid cell leukemia 1 | 0.0354811 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0353945 |
| CDH13 | cadherin 13 | 0.0350581 |
| ZNF292 | zinc finger protein 292 | 0.0350344 |
| TMEM132D | transmembrane protein 132D | 0.0341714 |
| SMYD3 | SET and MYND domain containing 3 | 0.0328423 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0328236 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0324015 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0319611 |
| CEP250 | centrosomal protein 250kDa | 0.0310999 |
| VCAN | versican | 0.0310343 |
| RTN4 | reticulon 4 | 0.0308649 |
| ENO1 | enolase 1, (alpha) | 0.0307637 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0304198 |
| FRMD5 | FERM domain containing 5 | 0.0302035 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0301119 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0298682 |
| SVIL | supervillin | 0.0298664 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0292512 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0292191 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0291568 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0290078 |
| LRRC7 | leucine rich repeat containing 7 | 0.028511 |
| SQSTM1 | sequestosome 1 | 0.0284496 |
| AFDN | afadin, adherens junction formation factor | 0.0283436 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0283302 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.028149 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.028146 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0280935 |
| CDK19 | cyclin-dependent kinase 19 | 0.0280504 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0276162 |
| FLOT1 | flotillin 1 | 0.0274433 |
| ASPH | aspartate beta-hydroxylase | 0.0272357 |
| EXOC4 | exocyst complex component 4 | 0.0270726 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0267972 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0267673 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0267659 |
| THBS1 | thrombospondin 1 | 0.0266518 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0264338 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0264244 |
| COL1A2 | collagen, type I, alpha 2 | 0.0263042 |
| MYLK | myosin light chain kinase | 0.0261717 |
| CENPF | centromere protein F, 350/400kDa | 0.025976 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0258072 |
| ZNF608 | zinc finger protein 608 | 0.025773 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0256771 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0252218 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0248067 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0247702 |
| EGFR | epidermal growth factor receptor | 0.0247514 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0247458 |
| SBF2 | SET binding factor 2 | 0.0247106 |
| ACTN1 | actinin, alpha 1 | 0.0243218 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.129572 |
| FTL | ferritin, light polypeptide | -0.0919747 |
| HLA-B | major histocompatibility complex, class I, B | -0.0883446 |
| MT2A | metallothionein 2A | -0.075984 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0660844 |
| VIM | vimentin | -0.0657708 |
| TMSB10 | thymosin beta 10 | -0.0638744 |
| KYNU | kynureninase | -0.0593284 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.058749 |
| B2M | beta-2-microglobulin | -0.0573565 |
| HLA-E | major histocompatibility complex, class I, E | -0.0511755 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0492575 |
| HLA-A | major histocompatibility complex, class I, A | -0.0464617 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0458639 |
| IER3 | immediate early response 3 | -0.0448767 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0437794 |
| RIGI | RNA sensor RIG-I | -0.0434102 |
| RPL12 | ribosomal protein L12 | -0.0428148 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0424715 |
| RPS3 | ribosomal protein S3 | -0.0396923 |
| PTMA | prothymosin, alpha | -0.0375994 |
| RPL36 | ribosomal protein L36 | -0.0372918 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0354689 |
| RPS6 | ribosomal protein S6 | -0.0337371 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0334023 |
| UBC | ubiquitin C | -0.0333032 |
| RPL37A | ribosomal protein L37a | -0.0331534 |
| RPL32 | ribosomal protein L32 | -0.0328085 |
| ADM | adrenomedullin | -0.0327837 |
| RPS19 | ribosomal protein S19 | -0.0325895 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0318044 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0312066 |
| RPLP2 | ribosomal protein, large, P2 | -0.0308953 |
| RPLP1 | ribosomal protein, large, P1 | -0.0308669 |
| RPL19 | ribosomal protein L19 | -0.0300392 |
| PMP22 | peripheral myelin protein 22 | -0.0291914 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0291092 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0285537 |
| RPL23 | ribosomal protein L23 | -0.0269248 |
| SP100 | SP100 nuclear antigen | -0.0267873 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0265245 |
| RPS13 | ribosomal protein S13 | -0.0264688 |
| RPS8 | ribosomal protein S8 | -0.0261848 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0260021 |
| RPS27A | ribosomal protein S27a | -0.0258176 |
| S100A9 | S100 calcium binding protein A9 | -0.0256681 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0256534 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0250075 |
| RACK1 | receptor for activated C kinase 1 | -0.0247991 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | -0.0247986 |
| RPS23 | ribosomal protein S23 | -0.0247725 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0246123 |
| PLSCR1 | phospholipid scramblase 1 | -0.0242466 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0237813 |
| TRIM22 | tripartite motif containing 22 | -0.0237463 |
| RPL31 | ribosomal protein L31 | -0.0227297 |
| RNF213 | ring finger protein 213 | -0.0225871 |
| RPS2 | ribosomal protein S2 | -0.0225427 |
| INHBA | inhibin, beta A | -0.0224963 |
| RPL36A | ribosomal protein L36a | -0.0218837 |
| RPS21 | ribosomal protein S21 | -0.0217127 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0216163 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0210513 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0209784 |
| RPS14 | ribosomal protein S14 | -0.0203464 |
| MX1 | MX dynamin-like GTPase 1 | -0.0201124 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.020043 |
| RPL28 | ribosomal protein L28 | -0.0199545 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0198028 |
| QKI | QKI, KH domain containing, RNA binding | -0.0197536 |
| RPS12 | ribosomal protein S12 | -0.0196501 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0195678 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0186967 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0185528 |
| IL6 | interleukin 6 | -0.0184887 |
| RND3 | Rho family GTPase 3 | -0.0183987 |
| GOPC | golgi-associated PDZ and coiled-coil motif containing | -0.0182348 |
| EGR1 | early growth response 1 | -0.0182031 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0181879 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0180125 |
| NTN4 | netrin 4 | -0.017955 |
| RPS10 | ribosomal protein S10 | -0.0179466 |
| ASTN2 | astrotactin 2 | -0.0178868 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.017524 |
| MX2 | MX dynamin-like GTPase 2 | -0.0175043 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.0173853 |
| RPS29 | ribosomal protein S29 | -0.0173753 |
| LOX | lysyl oxidase | -0.0172679 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.0172289 |
| RPL35 | ribosomal protein L35 | -0.017142 |
| RPL38 | ribosomal protein L38 | -0.016709 |
| TMSB4X | thymosin beta 4, X-linked | -0.0166137 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.0165896 |
| INTS6 | integrator complex subunit 6 | -0.016492 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0164346 |
| RPL8 | ribosomal protein L8 | -0.0163879 |
| RPL15 | ribosomal protein L15 | -0.016214 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0161905 |
| RPS15 | ribosomal protein S15 | -0.016007 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0157879 |
