Filopodium Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description Thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft. (Gene Ontology, GO_0030175)
External Link http://amigo.geneontology.org/amigo/term/GO:0030175
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Genes

69 proteins localized to the Filopodium cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
FSCN1 fascin actin-bundling protein 1 5.0
ARF6 ADP-ribosylation factor 6 5.0
TBC1D10C TBC1 domain family, member 10C 5.0
PALM paralemmin 5.0
PODXL podocalyxin-like 5.0
SYNE2 spectrin repeat containing, nuclear envelope 2 5.0
MYO3A myosin IIIA 5.0
KITLG KIT ligand 5.0
BAIAP2 BAI1-associated protein 2 5.0
PPP1R9B protein phosphatase 1, regulatory subunit 9B 5.0
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 5.0
CDC42 cell division cycle 42 5.0
MSN moesin 5.0
GAP43 growth associated protein 43 5.0
CIB1 calcium and integrin binding 1 (calmyrin) 5.0
CD302 CD302 molecule 5.0
ARL4C ADP-ribosylation factor-like 4C 5.0
ANTXR1 anthrax toxin receptor 1 5.0
SPEF1 sperm flagellar 1 5.0
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 5.0
SPATA13 spermatogenesis associated 13 5.0
MTM1 myotubularin 1 5.0
ABI1 abl-interactor 1 5.0
ABI2 abl-interactor 2 5.0
RIPOR2 RHO family interacting cell polarization regulator 2 5.0
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 5.0
ITGAV integrin, alpha V 5.0
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 5.0
ACTN2 actinin, alpha 2 5.0
EZR ezrin 5.0
IQGAP2 IQ motif containing GTPase activating protein 2 5.0
MORN4 MORN repeat containing 4 5.0
VASP vasodilator-stimulated phosphoprotein 5.0
MYO5A myosin VA (heavy chain 12, myoxin) 5.0
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 5.0
TUBB3 tubulin, beta 3 class III 4.0
TOX4 TOX high mobility group box family member 4 4.0
ABITRAM actin binding transcription modulator 4.0
GPM6A glycoprotein M6A 4.0
RDX radixin 4.0
SHTN1 shootin 1 4.0
UTRN utrophin 4.0
UNC5C unc-5 homolog C (C. elegans) 4.0
TM4SF19 transmembrane 4 L six family member 19 4.0
FMR1 fragile X mental retardation 1 4.0
PDPN podoplanin 4.0
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 4.0
CXADR coxsackie virus and adenovirus receptor 4.0
MYO1B myosin IB 4.0
DMD dystrophin 4.0
VIL1 villin 1 4.0
VCAM1 vascular cell adhesion molecule 1 4.0
TENM2 teneurin transmembrane protein 2 4.0
FGF13 fibroblast growth factor 13 4.0
MYO10 myosin X 3.0
FSCN3 fascin actin-bundling protein 3, testicular 3.0
ACTA2 actin, alpha 2, smooth muscle, aorta 3.0
NLGN1 neuroligin 1 3.0
METAP2 methionyl aminopeptidase 2 3.0
TRPV4 transient receptor potential cation channel, subfamily V, member 4 3.0
NF2 neurofibromin 2 (merlin) 3.0
ACTC1 actin, alpha, cardiac muscle 1 3.0
ACTA1 actin, alpha 1, skeletal muscle 3.0
MYO3B myosin IIIB 3.0
TWF2 twinfilin actin binding protein 2 3.0
ACTG2 actin, gamma 2, smooth muscle, enteric 3.0
TWF1 twinfilin actin binding protein 1 3.0
ERMN ermin, ERM-like protein 3.0
FYCO1 FYVE and coiled-coil domain containing 1 3.0