| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Finasteride perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Finasteride_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.19362 |
| PODXL | podocalyxin-like | 0.149648 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.112456 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0974905 |
| AHNAK | AHNAK nucleoprotein | 0.0813945 |
| FBN1 | fibrillin 1 | 0.0715382 |
| NAV1 | neuron navigator 1 | 0.0670156 |
| LOXL2 | lysyl oxidase-like 2 | 0.0659777 |
| APP | amyloid beta (A4) precursor protein | 0.0649408 |
| DST | dystonin | 0.0634277 |
| NAV2 | neuron navigator 2 | 0.0579367 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.054447 |
| CD44 | CD44 molecule (Indian blood group) | 0.0529581 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0521639 |
| THBS2 | thrombospondin 2 | 0.0517363 |
| GPC6 | glypican 6 | 0.0517342 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0511284 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0481254 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0481067 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0473494 |
| AUTS2 | autism susceptibility candidate 2 | 0.0469696 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0443002 |
| RUNX1 | runt-related transcription factor 1 | 0.0437529 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0432426 |
| COL5A1 | collagen, type V, alpha 1 | 0.0429395 |
| SEPTIN9 | septin 9 | 0.0413767 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0407435 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0406732 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0406025 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0399214 |
| COL5A2 | collagen, type V, alpha 2 | 0.0397653 |
| COL3A1 | collagen, type III, alpha 1 | 0.0391953 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0389231 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0382853 |
| CDH13 | cadherin 13 | 0.0378934 |
| TMSB4X | thymosin beta 4, X-linked | 0.0376163 |
| ATP13A3 | ATPase type 13A3 | 0.0375551 |
| SMYD3 | SET and MYND domain containing 3 | 0.0367581 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0360603 |
| FLNA | filamin A, alpha | 0.0356933 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0353143 |
| PRELID2 | PRELI domain containing 2 | 0.0350178 |
| EGFR | epidermal growth factor receptor | 0.0349226 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0347762 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0337733 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0334814 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0330101 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.032641 |
| MYOF | myoferlin | 0.0324584 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0323515 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0317969 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0317503 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0316069 |
| RAI14 | retinoic acid induced 14 | 0.0315827 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0315541 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0311667 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0307213 |
| GLIS3 | GLIS family zinc finger 3 | 0.0307119 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0303615 |
| ANXA2 | annexin A2 | 0.0296342 |
| LOX | lysyl oxidase | 0.0291306 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0290404 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0289161 |
| ANO6 | anoctamin 6 | 0.0287765 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0286894 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0286735 |
| SBF2 | SET binding factor 2 | 0.0284769 |
| TENM3 | teneurin transmembrane protein 3 | 0.0278344 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0278087 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0272817 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0272729 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0267998 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0267841 |
| TPM3 | tropomyosin 3 | 0.0267722 |
| CEP170 | centrosomal protein 170kDa | 0.0265621 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0263847 |
| CANX | calnexin | 0.0261405 |
| C1D | C1D nuclear receptor corepressor | 0.0259768 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0258682 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0257213 |
| FNIP1 | folliculin interacting protein 1 | 0.0256425 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.025596 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0254713 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0254489 |
| SP3 | Sp3 transcription factor | 0.0254107 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0250155 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0248521 |
| YEATS2 | YEATS domain containing 2 | 0.0248466 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0247305 |
| NEK7 | NIMA-related kinase 7 | 0.0246243 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0245873 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0240433 |
| CLIC4 | chloride intracellular channel 4 | 0.0239902 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0239566 |
| EHBP1 | EH domain binding protein 1 | 0.0237918 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0234025 |
| COL4A2 | collagen, type IV, alpha 2 | 0.023155 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0229869 |
| TDRD7 | tudor domain containing 7 | 0.0229346 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0228144 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.259055 |
| VIM | vimentin | -0.223871 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.201701 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.184052 |
| MT2A | metallothionein 2A | -0.132391 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.075507 |
| NDRG1 | N-myc downstream regulated 1 | -0.0750318 |
| PTMA | prothymosin, alpha | -0.0736568 |
| CSTB | cystatin B (stefin B) | -0.0620925 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0597933 |
| S100A6 | S100 calcium binding protein A6 | -0.0577399 |
| FTL | ferritin, light polypeptide | -0.0542497 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0531457 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0529996 |
| S100A10 | S100 calcium binding protein A10 | -0.051697 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0504687 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0498147 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0461366 |
| HLA-B | major histocompatibility complex, class I, B | -0.045766 |
| UBC | ubiquitin C | -0.037668 |
| PFN1 | profilin 1 | -0.0376283 |
| MT1X | metallothionein 1X | -0.0354987 |
| LMNA | lamin A/C | -0.0349599 |
| POTEF | POTE ankyrin domain family, member F | -0.0344779 |
| S100A11 | S100 calcium binding protein A11 | -0.033775 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0330727 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0329059 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0328671 |
| RPS19 | ribosomal protein S19 | -0.0315971 |
| RPS6 | ribosomal protein S6 | -0.0314649 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0313922 |
| RPLP2 | ribosomal protein, large, P2 | -0.0309804 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0296816 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0295838 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0285378 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0282396 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0269448 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0269207 |
| RPL37A | ribosomal protein L37a | -0.0268108 |
| ADM | adrenomedullin | -0.0267889 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0267187 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0266786 |
| RPL28 | ribosomal protein L28 | -0.0264593 |
| RPL23 | ribosomal protein L23 | -0.0260866 |
| RPL35A | ribosomal protein L35a | -0.0259331 |
| HLA-C | major histocompatibility complex, class I, C | -0.0258681 |
| B2M | beta-2-microglobulin | -0.0258479 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0258392 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0258166 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0257777 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0255474 |
| GNAS | GNAS complex locus | -0.025175 |
| SEC61G | Sec61 gamma subunit | -0.0251255 |
| PKM | pyruvate kinase, muscle | -0.0247892 |
| RPL36 | ribosomal protein L36 | -0.0244 |
| RPLP1 | ribosomal protein, large, P1 | -0.0241643 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0236588 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0235683 |
| TAGLN2 | transgelin 2 | -0.0233497 |
| IER3 | immediate early response 3 | -0.0225539 |
| S100A9 | S100 calcium binding protein A9 | -0.0221505 |
| FAM162A | family with sequence similarity 162, member A | -0.0219258 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0216645 |
| MAP1B | microtubule-associated protein 1B | -0.0215994 |
| SUCNR1 | succinate receptor 1 | -0.0214893 |
| MYADM | myeloid-associated differentiation marker | -0.021276 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0206382 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0206137 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0201217 |
| RPS14 | ribosomal protein S14 | -0.0200603 |
| RPL12 | ribosomal protein L12 | -0.0197669 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0194517 |
| BSG | basigin (Ok blood group) | -0.0192832 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0191846 |
| TPI1 | triosephosphate isomerase 1 | -0.0190167 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0189452 |
| RPL19 | ribosomal protein L19 | -0.0189387 |
| FOSL1 | FOS-like antigen 1 | -0.0187906 |
| RPS27 | ribosomal protein S27 | -0.0187059 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0186297 |
| KLF6 | Kruppel-like factor 6 | -0.017968 |
| RAB7A | RAB7A, member RAS oncogene family | -0.017839 |
| RPS13 | ribosomal protein S13 | -0.0178361 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0176331 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0174819 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0171663 |
| RPL31 | ribosomal protein L31 | -0.0171558 |
| CST3 | cystatin C | -0.0171351 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0169617 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0169548 |
| VKORC1 | vitamin K epoxide reductase complex, subunit 1 | -0.0169328 |
| GLRX | glutaredoxin (thioltransferase) | -0.0169287 |
| H3-3B | H3.3 histone B | -0.0167642 |
| FN1 | fibronectin 1 | -0.0166445 |
| RPS3 | ribosomal protein S3 | -0.0166029 |
| RPS8 | ribosomal protein S8 | -0.0163824 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0162666 |
| JUN | jun proto-oncogene | -0.0162339 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0162292 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0161438 |
