| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Finasteride perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Finasteride_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.146716 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.129799 |
| VIM | vimentin | 0.119259 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0948452 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0931597 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0872035 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0851968 |
| AREG | amphiregulin | 0.0812177 |
| TXNRD1 | thioredoxin reductase 1 | 0.0793161 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0783635 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0766967 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0756677 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0717055 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.070631 |
| TMEM41B | transmembrane protein 41B | 0.0705548 |
| VMP1 | vacuole membrane protein 1 | 0.0659038 |
| MATR3 | matrin 3 | 0.0599684 |
| MMP12 | matrix metallopeptidase 12 | 0.0590364 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0578529 |
| MED13L | mediator complex subunit 13-like | 0.0577725 |
| ANXA1 | annexin A1 | 0.0572762 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0558956 |
| CCNL1 | cyclin L1 | 0.0541385 |
| RTN4 | reticulon 4 | 0.0531004 |
| KIF5B | kinesin family member 5B | 0.0525191 |
| TNPO1 | transportin 1 | 0.0507969 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0502009 |
| NEK7 | NIMA-related kinase 7 | 0.0498333 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0492165 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0483896 |
| WDR43 | WD repeat domain 43 | 0.0481938 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0476586 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0472349 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0452385 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0446725 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0444886 |
| CPOX | coproporphyrinogen oxidase | 0.0444542 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0443892 |
| THOC1 | THO complex 1 | 0.0442335 |
| XPO1 | exportin 1 | 0.0439341 |
| RPL26 | ribosomal protein L26 | 0.043313 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0428606 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.041546 |
| PCBP2 | poly(rC) binding protein 2 | 0.041214 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0409575 |
| IPO7 | importin 7 | 0.040408 |
| ATP11A | ATPase, class VI, type 11A | 0.0401456 |
| YBX1 | Y box binding protein 1 | 0.0394911 |
| YAP1 | Yes-associated protein 1 | 0.0394783 |
| CDK17 | cyclin-dependent kinase 17 | 0.0382608 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0375267 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0373087 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0371637 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0370481 |
| RPS2 | ribosomal protein S2 | 0.036968 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0366145 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0364254 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0361329 |
| ZNF292 | zinc finger protein 292 | 0.0357543 |
| ZNF217 | zinc finger protein 217 | 0.0356791 |
| ENO1 | enolase 1, (alpha) | 0.0354804 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.035324 |
| GASK1B | golgi associated kinase 1B | 0.0352064 |
| PNN | pinin, desmosome associated protein | 0.034938 |
| PDGFC | platelet derived growth factor C | 0.0348938 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0347847 |
| RPL11 | ribosomal protein L11 | 0.0346731 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0338958 |
| ECT2 | epithelial cell transforming 2 | 0.0338071 |
| YBX3 | Y box binding protein 3 | 0.0332482 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0329855 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0327656 |
| TFG | TRK-fused gene | 0.0327071 |
| TPR | translocated promoter region, nuclear basket protein | 0.0326677 |
| CEP95 | centrosomal protein 95kDa | 0.0326487 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0325693 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0324742 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0324654 |
| NUP58 | nucleoporin 58 | 0.0321859 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0320843 |
| TBK1 | TANK-binding kinase 1 | 0.0320024 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0318416 |
| CLDND1 | claudin domain containing 1 | 0.0317244 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0314866 |
| AXIN2 | axin 2 | 0.0314695 |
| RACK1 | receptor for activated C kinase 1 | 0.0314024 |
| CLTC | clathrin, heavy chain (Hc) | 0.0312083 |
| RPLP0 | ribosomal protein, large, P0 | 0.0304651 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0301906 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0301553 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0299927 |
| TPM3 | tropomyosin 3 | 0.0294526 |
| HLA-A | major histocompatibility complex, class I, A | 0.0294346 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0290516 |
| LDHB | lactate dehydrogenase B | 0.0290142 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.028721 |
| RPS3 | ribosomal protein S3 | 0.0286991 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0286226 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0286026 |
| RPS8 | ribosomal protein S8 | 0.0284184 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | -0.146181 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.113295 |
| HMGA2 | high mobility group AT-hook 2 | -0.0924228 |
| EHBP1 | EH domain binding protein 1 | -0.0679945 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0665735 |
| INTS6 | integrator complex subunit 6 | -0.0588221 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0417597 |
| PCDH7 | protocadherin 7 | -0.0414942 |
| ZNF804A | zinc finger protein 804A | -0.0401289 |
| ADIPOR2 | adiponectin receptor 2 | -0.0400175 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0389738 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0358423 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0344446 |
| RASAL2 | RAS protein activator like 2 | -0.0344063 |
| NABP1 | nucleic acid binding protein 1 | -0.0322015 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.03146 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0310711 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0302016 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0298346 |
| EGR1 | early growth response 1 | -0.0292704 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0291492 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0286738 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | -0.0269359 |
| CMIP | c-Maf inducing protein | -0.025273 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0252419 |
| LRRC23 | leucine rich repeat containing 23 | -0.0245603 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0243655 |
| RNF213 | ring finger protein 213 | -0.0240527 |
| FSTL5 | follistatin-like 5 | -0.0237532 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0236786 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.0236342 |
| CUX1 | cut-like homeobox 1 | -0.0235677 |
| ACTG1 | actin gamma 1 | -0.023009 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0228878 |
| DTNA | dystrobrevin, alpha | -0.0228631 |
| CEP112 | centrosomal protein 112kDa | -0.0228389 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0228024 |
| TBCA | tubulin folding cofactor A | -0.0227918 |
| BPTF | bromodomain PHD finger transcription factor | -0.0225058 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0224487 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.02212 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0220583 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | -0.0214699 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0200591 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0190223 |
| ETV6 | ets variant 6 | -0.0187248 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0186554 |
| KSR2 | kinase suppressor of ras 2 | -0.0182427 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0180159 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0179228 |
| SETX | senataxin | -0.0178202 |
| SYT1 | synaptotagmin I | -0.0177165 |
| AEBP2 | AE binding protein 2 | -0.0175431 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0174235 |
| DENND5A | DENN/MADD domain containing 5A | -0.0172024 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0171198 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0170733 |
| GPHN | gephyrin | -0.0170652 |
| BNC2 | basonuclin 2 | -0.0170487 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0169002 |
| MYOM1 | myomesin 1 | -0.0168227 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0166328 |
| DMXL1 | Dmx-like 1 | -0.0166077 |
| NBEAL1 | neurobeachin-like 1 | -0.0165413 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.016361 |
| SSH2 | slingshot protein phosphatase 2 | -0.0162299 |
| COL5A2 | collagen, type V, alpha 2 | -0.016097 |
| CLDN1 | claudin 1 | -0.0160053 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0159186 |
| DUSP16 | dual specificity phosphatase 16 | -0.0157312 |
| EGFR | epidermal growth factor receptor | -0.0157254 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0157001 |
| MYPN | myopalladin | -0.0156837 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0156285 |
| MED12L | mediator complex subunit 12-like | -0.0155272 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0155241 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0155142 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0154271 |
| NHSL1 | NHS-like 1 | -0.015421 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0153351 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0152818 |
| UBAP2 | ubiquitin associated protein 2 | -0.0152316 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0149817 |
| DIAPH2 | diaphanous-related formin 2 | -0.0148305 |
| R3HDM2 | R3H domain containing 2 | -0.0147904 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0147652 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0146796 |
| THADA | thyroid adenoma associated | -0.0145162 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0145139 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0144796 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0144 |
| ZNF407 | zinc finger protein 407 | -0.0142594 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0142578 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0140635 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0140455 |
| AK1 | adenylate kinase 1 | -0.0140316 |
| MECOM | MDS1 and EVI1 complex locus | -0.0140201 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | -0.0139497 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0139256 |
| TMEM108 | transmembrane protein 108 | -0.0139127 |
