| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Finasteride perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Finasteride_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0966411 |
| VEGFA | vascular endothelial growth factor A | 0.08736 |
| B2M | beta-2-microglobulin | 0.0861101 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0828878 |
| NDRG1 | N-myc downstream regulated 1 | 0.0760561 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0713469 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0605572 |
| RNF149 | ring finger protein 149 | 0.0561696 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0452618 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0431574 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0414569 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0411821 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0408111 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0395408 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0381856 |
| PTEN | phosphatase and tensin homolog | 0.0368703 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0360328 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0359945 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0358323 |
| SBF2 | SET binding factor 2 | 0.0356589 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0351956 |
| ABHD2 | abhydrolase domain containing 2 | 0.0351693 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.0337706 |
| RAD51B | RAD51 paralog B | 0.0336843 |
| DIAPH3 | diaphanous-related formin 3 | 0.0336478 |
| GOLGB1 | golgin B1 | 0.033412 |
| MKI67 | marker of proliferation Ki-67 | 0.0331578 |
| RPS6 | ribosomal protein S6 | 0.0315143 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0304287 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0304184 |
| RNF145 | ring finger protein 145 | 0.0299358 |
| AOPEP | aminopeptidase O (putative) | 0.02975 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0294165 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0286765 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0286675 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0277062 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0276342 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0270985 |
| CCNL1 | cyclin L1 | 0.0270296 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0265945 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0265907 |
| USP3 | ubiquitin specific peptidase 3 | 0.0265388 |
| DENND4C | DENN/MADD domain containing 4C | 0.0264816 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0263751 |
| NCOR1 | nuclear receptor corepressor 1 | 0.026357 |
| GOLGA2 | golgin A2 | 0.026209 |
| RPL35A | ribosomal protein L35a | 0.0259621 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0259614 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0258838 |
| YEATS2 | YEATS domain containing 2 | 0.0257148 |
| GOLGA4 | golgin A4 | 0.0255205 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0254283 |
| TXNIP | thioredoxin interacting protein | 0.0251967 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0245256 |
| PLIN2 | perilipin 2 | 0.0242066 |
| HELZ | helicase with zinc finger | 0.0240593 |
| ZNF395 | zinc finger protein 395 | 0.0236838 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0232778 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0229622 |
| GRAMD2B | GRAM domain containing 2B | 0.0229616 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0229596 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 | 0.0228116 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0227192 |
| CDC42SE2 | CDC42 small effector 2 | 0.0226449 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0222812 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0222533 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 0.0222185 |
| TPR | translocated promoter region, nuclear basket protein | 0.0221368 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0220024 |
| RLF | rearranged L-myc fusion | 0.0219548 |
| THOC2 | THO complex 2 | 0.0218449 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0217801 |
| ALPK1 | alpha-kinase 1 | 0.0214341 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.0211815 |
| SP3 | Sp3 transcription factor | 0.0211006 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0209565 |
| RBM39 | RNA binding motif protein 39 | 0.0209129 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0208142 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0208115 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0205889 |
| ARRDC3 | arrestin domain containing 3 | 0.020553 |
| KIF16B | kinesin family member 16B | 0.0202899 |
| STK39 | serine threonine kinase 39 | 0.0201774 |
| FNIP1 | folliculin interacting protein 1 | 0.0200781 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0200035 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0199475 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | 0.0199361 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.019922 |
| TMEM245 | transmembrane protein 245 | 0.0196753 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0195702 |
| ANXA4 | annexin A4 | 0.0194359 |
| CEP95 | centrosomal protein 95kDa | 0.019356 |
| USP47 | ubiquitin specific peptidase 47 | 0.0193046 |
| ATP11B | ATPase, class VI, type 11B | 0.0192531 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0192285 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0191529 |
| NBR1 | neighbor of BRCA1 gene 1 | 0.0190931 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0190554 |
| CCDC14 | coiled-coil domain containing 14 | 0.0188975 |
| COG6 | component of oligomeric golgi complex 6 | 0.0188656 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.197546 |
| LMO7 | LIM domain 7 | -0.157478 |
| INTS6 | integrator complex subunit 6 | -0.141511 |
| RNF213 | ring finger protein 213 | -0.132459 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.127664 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.125694 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.121034 |
| ANXA2 | annexin A2 | -0.105605 |
| PERP | PERP, TP53 apoptosis effector | -0.0950345 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0880082 |
| PLSCR1 | phospholipid scramblase 1 | -0.0877993 |
| VCL | vinculin | -0.0835293 |
| RIGI | RNA sensor RIG-I | -0.0831569 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0828473 |
| PKM | pyruvate kinase, muscle | -0.0814969 |
| MX2 | MX dynamin-like GTPase 2 | -0.078964 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0768864 |
| JUN | jun proto-oncogene | -0.0757263 |
| MYO1E | myosin IE | -0.072913 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0724072 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0718055 |
| TJP1 | tight junction protein 1 | -0.0687132 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.068617 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0652185 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0650694 |
| SP100 | SP100 nuclear antigen | -0.0626088 |
| MX1 | MX dynamin-like GTPase 1 | -0.0614283 |
| EZR | ezrin | -0.0611665 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0609066 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0608112 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0592452 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0591837 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.057663 |
| PLSCR2 | phospholipid scramblase 2 | -0.0573097 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0562755 |
| EGR1 | early growth response 1 | -0.0560791 |
| AHNAK | AHNAK nucleoprotein | -0.0555725 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0551181 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0548232 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0533756 |
| MAP7 | microtubule-associated protein 7 | -0.0528136 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0515492 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0514081 |
| LAMA4 | laminin, alpha 4 | -0.0513762 |
| TMC5 | transmembrane channel-like 5 | -0.0510184 |
| ACTN4 | actinin, alpha 4 | -0.0509361 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0508059 |
| EFNB2 | ephrin-B2 | -0.0504111 |
| AREG | amphiregulin | -0.0501918 |
| SQSTM1 | sequestosome 1 | -0.0500898 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0495073 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0491904 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0488072 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.048368 |
| SPAG9 | sperm associated antigen 9 | -0.0477036 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0475637 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0465238 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | -0.0449601 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0447376 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0442063 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0438067 |
| POF1B | premature ovarian failure, 1B | -0.0429328 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0421212 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0420664 |
| ETV6 | ets variant 6 | -0.0418783 |
| EPCAM | epithelial cell adhesion molecule | -0.0416724 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0416298 |
| LCN2 | lipocalin 2 | -0.0415569 |
| SDC4 | syndecan 4 | -0.0410678 |
| ERBIN | erbb2 interacting protein | -0.0409364 |
| STK24 | serine/threonine kinase 24 | -0.0405912 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0402416 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0402298 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.040223 |
| MCU | mitochondrial calcium uniporter | -0.0394328 |
| XAF1 | XIAP associated factor 1 | -0.0393759 |
| MCL1 | myeloid cell leukemia 1 | -0.0385072 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0380611 |
| UBAP2 | ubiquitin associated protein 2 | -0.0379673 |
| NABP1 | nucleic acid binding protein 1 | -0.037961 |
| S100A10 | S100 calcium binding protein A10 | -0.0376787 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0372177 |
| ZNF207 | zinc finger protein 207 | -0.0368972 |
| HLA-E | major histocompatibility complex, class I, E | -0.0364539 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0361452 |
| IRS2 | insulin receptor substrate 2 | -0.0360227 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0359644 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0358243 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0351219 |
| TMSB10 | thymosin beta 10 | -0.0343691 |
| NCKAP5 | NCK-associated protein 5 | -0.0342765 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.033902 |
| SETX | senataxin | -0.0334924 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0334606 |
| SMAD3 | SMAD family member 3 | -0.0334274 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0328962 |
| HKDC1 | hexokinase domain containing 1 | -0.0325001 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.031979 |
| PHF3 | PHD finger protein 3 | -0.0315882 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0311816 |
