| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Finasteride perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Finasteride_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.180964 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.113838 |
| VEGFA | vascular endothelial growth factor A | 0.10277 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0844871 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.082874 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0805732 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.076901 |
| CADM1 | cell adhesion molecule 1 | 0.0760818 |
| ATP13A3 | ATPase type 13A3 | 0.076048 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0692142 |
| RPS6 | ribosomal protein S6 | 0.0655318 |
| LOXL2 | lysyl oxidase-like 2 | 0.0585764 |
| ZNF292 | zinc finger protein 292 | 0.0556982 |
| PTMA | prothymosin, alpha | 0.0551371 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0540875 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0528096 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0519676 |
| RPL11 | ribosomal protein L11 | 0.0503216 |
| RLF | rearranged L-myc fusion | 0.047045 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0447566 |
| CANX | calnexin | 0.043873 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0435142 |
| GOLGA4 | golgin A4 | 0.0428465 |
| RASA2 | RAS p21 protein activator 2 | 0.0426151 |
| MT2A | metallothionein 2A | 0.0420691 |
| FN1 | fibronectin 1 | 0.0419588 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0412685 |
| ARRDC3 | arrestin domain containing 3 | 0.0393883 |
| QKI | QKI, KH domain containing, RNA binding | 0.0392541 |
| RNF145 | ring finger protein 145 | 0.0383109 |
| RPL26 | ribosomal protein L26 | 0.0382022 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0381331 |
| YBX1 | Y box binding protein 1 | 0.0377996 |
| RPL7 | ribosomal protein L7 | 0.0377353 |
| RPL35A | ribosomal protein L35a | 0.0376131 |
| USP3 | ubiquitin specific peptidase 3 | 0.0374756 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0367294 |
| TFG | TRK-fused gene | 0.0362985 |
| RPS3 | ribosomal protein S3 | 0.0354943 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0352935 |
| SPAG9 | sperm associated antigen 9 | 0.0351447 |
| PDE10A | phosphodiesterase 10A | 0.0350821 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0333105 |
| FMNL2 | formin-like 2 | 0.0330302 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0329858 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0328867 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0324018 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0317369 |
| PDE8A | phosphodiesterase 8A | 0.030995 |
| IRF1 | interferon regulatory factor 1 | 0.0301465 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0301327 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0300959 |
| MATR3 | matrin 3 | 0.0297649 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0296367 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0294583 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0286617 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0286558 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.028353 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0283249 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.028091 |
| MRTFA | myocardin related transcription factor A | 0.0280623 |
| RPS2 | ribosomal protein S2 | 0.0280206 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0274342 |
| SMAD3 | SMAD family member 3 | 0.0272538 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0267465 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0266934 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0263509 |
| B2M | beta-2-microglobulin | 0.0261438 |
| FOXJ3 | forkhead box J3 | 0.026065 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0253213 |
| PTK2 | protein tyrosine kinase 2 | 0.0247834 |
| ANXA5 | annexin A5 | 0.0244757 |
| RBM39 | RNA binding motif protein 39 | 0.0241675 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0241206 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0240925 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.024059 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0240358 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0240228 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0239912 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0237222 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0235462 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0235371 |
| RYK | receptor-like tyrosine kinase | 0.0235069 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0232724 |
| CABIN1 | calcineurin binding protein 1 | 0.0230313 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0230282 |
| RPL13A | ribosomal protein L13a | 0.0228822 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0228238 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0227507 |
| HELZ | helicase with zinc finger | 0.0224142 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0224133 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0224124 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0223827 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0221573 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0220705 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0219945 |
| CCNL1 | cyclin L1 | 0.0218674 |
| RPS19 | ribosomal protein S19 | 0.0217998 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0217925 |
| RPS12 | ribosomal protein S12 | 0.0217456 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.227268 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.19637 |
| COL1A1 | collagen, type I, alpha 1 | -0.1613 |
| COL1A2 | collagen, type I, alpha 2 | -0.138471 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.126779 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.114506 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.110068 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.106955 |
| ASPH | aspartate beta-hydroxylase | -0.101117 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0921057 |
| UBC | ubiquitin C | -0.0847681 |
| TMSB10 | thymosin beta 10 | -0.0812927 |
| ENO1 | enolase 1, (alpha) | -0.0747932 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0688764 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0681902 |
| GLIS3 | GLIS family zinc finger 3 | -0.0612214 |
| CD44 | CD44 molecule (Indian blood group) | -0.0596591 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0595533 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.058899 |
| VCL | vinculin | -0.0582764 |
| FBN1 | fibrillin 1 | -0.0543382 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0542283 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0521621 |
| NDRG1 | N-myc downstream regulated 1 | -0.0509007 |
| DPYD | dihydropyrimidine dehydrogenase | -0.049908 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0482109 |
| CALD1 | caldesmon 1 | -0.048114 |
| TPM4 | tropomyosin 4 | -0.0478582 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.046869 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0451259 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0447121 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0429316 |
| NAV1 | neuron navigator 1 | -0.0424274 |
| IL6ST | interleukin 6 signal transducer | -0.0422081 |
| NRP1 | neuropilin 1 | -0.0408231 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0398666 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0398264 |
| LDHA | lactate dehydrogenase A | -0.0390113 |
| POTEF | POTE ankyrin domain family, member F | -0.0389971 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0384145 |
| VCAN | versican | -0.0382283 |
| OSMR | oncostatin M receptor | -0.0380758 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0374945 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.037312 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0371293 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0369882 |
| ATXN1 | ataxin 1 | -0.0368428 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0367931 |
| CNTN5 | contactin 5 | -0.0360746 |
| MAP1B | microtubule-associated protein 1B | -0.0360361 |
| HLA-B | major histocompatibility complex, class I, B | -0.0351906 |
| INHBA | inhibin, beta A | -0.0347208 |
| PKM | pyruvate kinase, muscle | -0.0344818 |
| HMGA2 | high mobility group AT-hook 2 | -0.0341505 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0335489 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0332896 |
| EGR1 | early growth response 1 | -0.033039 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0310704 |
| MT1X | metallothionein 1X | -0.0309432 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.030523 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0302994 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0300894 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0296528 |
| CDH13 | cadherin 13 | -0.0294854 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0293578 |
| SDC2 | syndecan 2 | -0.0293515 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0292683 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0289071 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0283818 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0280996 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.028014 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0277884 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0275944 |
| IL6 | interleukin 6 | -0.0268262 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0267675 |
| S100A6 | S100 calcium binding protein A6 | -0.0267469 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0266397 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0262783 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0255646 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0255528 |
| ZNF644 | zinc finger protein 644 | -0.0255524 |
| FOXP1 | forkhead box P1 | -0.0250801 |
| NEK10 | NIMA-related kinase 10 | -0.0248232 |
| CUX1 | cut-like homeobox 1 | -0.0240783 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.023949 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0237168 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0237103 |
| PALLD | palladin, cytoskeletal associated protein | -0.0233876 |
| COL5A1 | collagen, type V, alpha 1 | -0.0232632 |
| RPS27A | ribosomal protein S27a | -0.0231467 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0230023 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0228751 |
| TAGLN2 | transgelin 2 | -0.0228565 |
| CLIC4 | chloride intracellular channel 4 | -0.0228008 |
| AHNAK | AHNAK nucleoprotein | -0.0226841 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0222761 |
| NREP | neuronal regeneration related protein | -0.0222509 |
| CALU | calumenin | -0.0222454 |
| ACTG1 | actin gamma 1 | -0.0220805 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0219722 |
