| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Finasteride perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Finasteride_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.124324 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.105696 |
| EREG | epiregulin | 0.0880045 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0876965 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0865625 |
| NDRG1 | N-myc downstream regulated 1 | 0.0798925 |
| MED13L | mediator complex subunit 13-like | 0.0778799 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0682395 |
| RNF145 | ring finger protein 145 | 0.067265 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0607686 |
| FAM13A | family with sequence similarity 13, member A | 0.0593265 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0589021 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0573201 |
| FAT1 | FAT atypical cadherin 1 | 0.0569824 |
| RBM39 | RNA binding motif protein 39 | 0.0559171 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0552911 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0551431 |
| GOLGA4 | golgin A4 | 0.054872 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0537145 |
| TNS4 | tensin 4 | 0.0528713 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0519119 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.051741 |
| SPAG9 | sperm associated antigen 9 | 0.0506465 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0504898 |
| LMO7 | LIM domain 7 | 0.0499092 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0492452 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0488712 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0487041 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0479609 |
| ZNF292 | zinc finger protein 292 | 0.0471569 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0463035 |
| SETD5 | SET domain containing 5 | 0.0457963 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0448654 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0442727 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0433233 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0429367 |
| TXNIP | thioredoxin interacting protein | 0.0425585 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0416277 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0412362 |
| NUP58 | nucleoporin 58 | 0.0397069 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0394867 |
| CCNL1 | cyclin L1 | 0.0394044 |
| OGA | O-GlcNAcase | 0.0392845 |
| RREB1 | ras responsive element binding protein 1 | 0.0384056 |
| YME1L1 | YME1-like 1 ATPase | 0.0381216 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0380498 |
| LRRC1 | leucine rich repeat containing 1 | 0.0373821 |
| KIF5B | kinesin family member 5B | 0.0368913 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0366751 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0362085 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0360652 |
| COG5 | component of oligomeric golgi complex 5 | 0.0357466 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.035583 |
| TFG | TRK-fused gene | 0.0355565 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0355469 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0352762 |
| B2M | beta-2-microglobulin | 0.0347518 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0345476 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0343753 |
| WDR43 | WD repeat domain 43 | 0.0342217 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0340643 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0336142 |
| ARF4 | ADP-ribosylation factor 4 | 0.0334463 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0331416 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0329831 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0329514 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0328073 |
| MXD1 | MAX dimerization protein 1 | 0.0327722 |
| NEK7 | NIMA-related kinase 7 | 0.0325513 |
| COPA | coatomer protein complex, subunit alpha | 0.0325471 |
| FOXJ3 | forkhead box J3 | 0.0323998 |
| USP3 | ubiquitin specific peptidase 3 | 0.0322532 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.032142 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0319778 |
| TMSB4X | thymosin beta 4, X-linked | 0.0316584 |
| ABHD2 | abhydrolase domain containing 2 | 0.0314134 |
| SRP54 | signal recognition particle 54kDa | 0.0312585 |
| CCNY | cyclin Y | 0.0310957 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0310677 |
| NCKAP1 | NCK-associated protein 1 | 0.0310569 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0309327 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.030576 |
| AREG | amphiregulin | 0.0303486 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0301461 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0298983 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0297681 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0297526 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0294414 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0294049 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.029364 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0292872 |
| TOP1 | topoisomerase (DNA) I | 0.0292409 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0290887 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0289179 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0289049 |
| HELZ | helicase with zinc finger | 0.0288774 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0288396 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0287215 |
| SARS1 | seryl-tRNA synthetase 1 | 0.028706 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0284444 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.250547 |
| NPSR1 | neuropeptide S receptor 1 | -0.140585 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.131076 |
| PTMA | prothymosin, alpha | -0.113161 |
| TMSB10 | thymosin beta 10 | -0.10786 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0915169 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0900436 |
| ACTG1 | actin gamma 1 | -0.0810885 |
| AHNAK | AHNAK nucleoprotein | -0.0809596 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0668818 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0639932 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0583271 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0577358 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0558105 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0557018 |
| RPLP1 | ribosomal protein, large, P1 | -0.0541762 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0516342 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0503237 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0498542 |
| LDHA | lactate dehydrogenase A | -0.0485732 |
| AGR2 | anterior gradient 2 | -0.0464011 |
| FTL | ferritin, light polypeptide | -0.0462181 |
| CCND1 | cyclin D1 | -0.0456394 |
| RPS8 | ribosomal protein S8 | -0.0444258 |
| LMNA | lamin A/C | -0.0429048 |
| POF1B | premature ovarian failure, 1B | -0.0406142 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0399283 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0364328 |
| ITGA6 | integrin, alpha 6 | -0.0360492 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0352869 |
| KRT18 | keratin 18, type I | -0.0351405 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0350657 |
| SLC35F3 | solute carrier family 35, member F3 | -0.035063 |
| HMGA1 | high mobility group AT-hook 1 | -0.034712 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0346533 |
| HMGB1 | high mobility group box 1 | -0.0344244 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0330691 |
| ONECUT3 | one cut homeobox 3 | -0.0319951 |
| LAMA4 | laminin, alpha 4 | -0.0311964 |
| RPL27A | ribosomal protein L27a | -0.0310818 |
| ASPH | aspartate beta-hydroxylase | -0.0303961 |
| EZR | ezrin | -0.0299878 |
| RPLP0 | ribosomal protein, large, P0 | -0.0299005 |
| EHBP1 | EH domain binding protein 1 | -0.0295807 |
| COBL | cordon-bleu WH2 repeat protein | -0.0291601 |
| KRT19 | keratin 19, type I | -0.028835 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0283482 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0283416 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0282857 |
| EFNB2 | ephrin-B2 | -0.0281937 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0281913 |
| MT2A | metallothionein 2A | -0.028119 |
| CADPS | Ca++-dependent secretion activator | -0.0280305 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.027497 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0270219 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0268276 |
| S100A6 | S100 calcium binding protein A6 | -0.0262742 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0262208 |
| NBEAL1 | neurobeachin-like 1 | -0.0257557 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0255219 |
| S100A10 | S100 calcium binding protein A10 | -0.0255083 |
| RPL8 | ribosomal protein L8 | -0.0254923 |
| CLOCK | clock circadian regulator | -0.0250535 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.024722 |
| FHIT | fragile histidine triad | -0.0246799 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0246753 |
| GNAS | GNAS complex locus | -0.024628 |
| MT1X | metallothionein 1X | -0.0243221 |
| MYO1E | myosin IE | -0.0243026 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.024298 |
| ANXA1 | annexin A1 | -0.0242599 |
| ARF1 | ADP-ribosylation factor 1 | -0.024147 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0238189 |
| RRBP1 | ribosome binding protein 1 | -0.0237905 |
| SH3D19 | SH3 domain containing 19 | -0.0236518 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0236406 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0236113 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0234666 |
| RPL28 | ribosomal protein L28 | -0.0233704 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0233392 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0228769 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0228313 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.022557 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0224161 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0221079 |
| PFN1 | profilin 1 | -0.0220961 |
| EMP1 | epithelial membrane protein 1 | -0.022005 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0219937 |
| SVIL | supervillin | -0.0219718 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.021853 |
| RPS4X | ribosomal protein S4, X-linked | -0.0218381 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0216351 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0215667 |
| AEBP2 | AE binding protein 2 | -0.0215119 |
| RNF217 | ring finger protein 217 | -0.0215008 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0214876 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0210959 |
| TUBA1B | tubulin, alpha 1b | -0.0209806 |
| RPS19 | ribosomal protein S19 | -0.0209703 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0209257 |
