| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Finasteride perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Finasteride_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.282289 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.159851 |
| GOLGA4 | golgin A4 | 0.121225 |
| SMAD3 | SMAD family member 3 | 0.113919 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.103705 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.094808 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.087394 |
| RBM39 | RNA binding motif protein 39 | 0.0834292 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0813045 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0805742 |
| FAM13A | family with sequence similarity 13, member A | 0.0784469 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0734946 |
| PCBP2 | poly(rC) binding protein 2 | 0.0690199 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0601753 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0601212 |
| NAV2 | neuron navigator 2 | 0.0599864 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0578165 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0565719 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.056169 |
| ZNF292 | zinc finger protein 292 | 0.0561446 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0550943 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0539436 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0538477 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0537962 |
| PRELID2 | PRELI domain containing 2 | 0.052201 |
| VEGFA | vascular endothelial growth factor A | 0.050831 |
| OGA | O-GlcNAcase | 0.0505153 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0499718 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0498347 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.048986 |
| COG5 | component of oligomeric golgi complex 5 | 0.0487534 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0474073 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0467544 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0463613 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0456047 |
| SBF2 | SET binding factor 2 | 0.0455681 |
| CANX | calnexin | 0.0449185 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0441694 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0434985 |
| MYOF | myoferlin | 0.0434021 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0429166 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.041927 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0417557 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0405033 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0403794 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0396284 |
| ANXA1 | annexin A1 | 0.0392411 |
| RUNX1 | runt-related transcription factor 1 | 0.0391515 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0383111 |
| USP34 | ubiquitin specific peptidase 34 | 0.0377749 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0373895 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0373151 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0371813 |
| CALU | calumenin | 0.0368188 |
| EFNA5 | ephrin-A5 | 0.0362814 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0362315 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0359786 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0359573 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0358526 |
| SPAG9 | sperm associated antigen 9 | 0.0358083 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0357402 |
| NBAS | neuroblastoma amplified sequence | 0.0354874 |
| FLNB | filamin B, beta | 0.0353707 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0349038 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.034659 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0339905 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0338015 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0337629 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0337039 |
| ARF4 | ADP-ribosylation factor 4 | 0.0336761 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0335241 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0333527 |
| HELZ | helicase with zinc finger | 0.0333308 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0332717 |
| HDLBP | high density lipoprotein binding protein | 0.032936 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0325334 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0320049 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0319326 |
| ARRDC3 | arrestin domain containing 3 | 0.0318918 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0317612 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0317546 |
| SUCO | SUN domain containing ossification factor | 0.0316411 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0315223 |
| YBX1 | Y box binding protein 1 | 0.0314472 |
| OSMR | oncostatin M receptor | 0.0308019 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0305192 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0305075 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0304083 |
| SIK3 | SIK family kinase 3 | 0.0301065 |
| YEATS2 | YEATS domain containing 2 | 0.0300941 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0300893 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.029847 |
| FOXO3 | forkhead box O3 | 0.0297092 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0296479 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0293882 |
| APP | amyloid beta (A4) precursor protein | 0.0293528 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0289128 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0288089 |
| SETD5 | SET domain containing 5 | 0.0287743 |
| RARB | retinoic acid receptor, beta | 0.0286786 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.138187 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.128983 |
| TMSB10 | thymosin beta 10 | -0.111256 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.105707 |
| NRG1 | neuregulin 1 | -0.10418 |
| HMGA2 | high mobility group AT-hook 2 | -0.102659 |
| CDH13 | cadherin 13 | -0.0771401 |
| GLCCI1 | glucocorticoid induced 1 | -0.0751424 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0738494 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0689385 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0684075 |
| MTSS1 | metastasis suppressor 1 | -0.0632561 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0549423 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.054527 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0537666 |
| AADAC | arylacetamide deacetylase | -0.0514408 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0495966 |
| NTN4 | netrin 4 | -0.0465202 |
| PTMA | prothymosin, alpha | -0.0458937 |
| LOX | lysyl oxidase | -0.0453037 |
| FBN1 | fibrillin 1 | -0.045084 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0449936 |
| VIM | vimentin | -0.04449 |
| CDK14 | cyclin-dependent kinase 14 | -0.0432987 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0421117 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0417553 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0416907 |
| CLMP | CXADR-like membrane protein | -0.0414427 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0403618 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.040213 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0367427 |
| S100A6 | S100 calcium binding protein A6 | -0.0366068 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0361783 |
| CUX1 | cut-like homeobox 1 | -0.0355661 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0351809 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0351661 |
| ANTXR2 | anthrax toxin receptor 2 | -0.034844 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0331323 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0321684 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0319585 |
| IL1B | interleukin 1, beta | -0.0318571 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0313659 |
| STC1 | stanniocalcin 1 | -0.0309944 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0307835 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0305754 |
| GLIS3 | GLIS family zinc finger 3 | -0.0303157 |
| IFI44L | interferon-induced protein 44-like | -0.0302829 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0301902 |
| MECOM | MDS1 and EVI1 complex locus | -0.0298607 |
| VCL | vinculin | -0.0295284 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0289554 |
| WLS | wntless Wnt ligand secretion mediator | -0.0289307 |
| EGR1 | early growth response 1 | -0.0289064 |
| PRRX1 | paired related homeobox 1 | -0.0287235 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0286597 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0281671 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0280745 |
| VRK2 | vaccinia related kinase 2 | -0.0278892 |
| NLK | nemo-like kinase | -0.0277461 |
| RPL35A | ribosomal protein L35a | -0.0275832 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0273064 |
| NAV1 | neuron navigator 1 | -0.0271859 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0270896 |
| INTS6 | integrator complex subunit 6 | -0.0269284 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0267776 |
| ZNF804A | zinc finger protein 804A | -0.0266287 |
| ENOSF1 | enolase superfamily member 1 | -0.026346 |
| NUMB | numb homolog (Drosophila) | -0.026203 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.02619 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0260397 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0255115 |
| ANXA10 | annexin A10 | -0.0253651 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0252989 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0247813 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0244679 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0241692 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0240485 |
| TGFB1 | transforming growth factor, beta 1 | -0.0240338 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0239608 |
| SEPTIN9 | septin 9 | -0.0234565 |
| HLA-B | major histocompatibility complex, class I, B | -0.0232262 |
| SP100 | SP100 nuclear antigen | -0.0231065 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0230906 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0228377 |
| RAI14 | retinoic acid induced 14 | -0.022325 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0222754 |
| RNF213 | ring finger protein 213 | -0.0222323 |
| PRSS23 | protease, serine, 23 | -0.0221198 |
| FTL | ferritin, light polypeptide | -0.0219016 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0218771 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0218583 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0215977 |
| SYT1 | synaptotagmin I | -0.0215156 |
| RPS19 | ribosomal protein S19 | -0.0214933 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0213564 |
| S100A10 | S100 calcium binding protein A10 | -0.0213218 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.021221 |
| DNER | delta/notch-like EGF repeat containing | -0.0211243 |
| RASAL2 | RAS protein activator like 2 | -0.0209962 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0208855 |
