| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Finasteride perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Finasteride_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.180288 |
| PM20D1 | peptidase M20 domain containing 1 | 0.137565 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.133165 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0842465 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0782701 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0719996 |
| GRAMD1B | GRAM domain containing 1B | 0.0667058 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0579133 |
| WWOX | WW domain containing oxidoreductase | 0.0542148 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0535676 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0509672 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0496535 |
| TPM3 | tropomyosin 3 | 0.0496355 |
| FGB | fibrinogen beta chain | 0.0471881 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0463825 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0449763 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0449506 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0448406 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0417501 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.041706 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0379602 |
| RPL26 | ribosomal protein L26 | 0.0316691 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0313679 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.031298 |
| MKI67 | marker of proliferation Ki-67 | 0.030306 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.029779 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0291416 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0290579 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0289609 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0287155 |
| RPS12 | ribosomal protein S12 | 0.0285793 |
| CANX | calnexin | 0.0272547 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0271091 |
| RRM2 | ribonucleotide reductase M2 | 0.0269151 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0266381 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0262023 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0259259 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0257523 |
| RPS18 | ribosomal protein S18 | 0.025039 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0250178 |
| PNN | pinin, desmosome associated protein | 0.0236773 |
| JAK1 | Janus kinase 1 | 0.0231037 |
| RPL4 | ribosomal protein L4 | 0.022994 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0225117 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.022153 |
| CENPF | centromere protein F, 350/400kDa | 0.0220085 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0210409 |
| APP | amyloid beta (A4) precursor protein | 0.0206864 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.020642 |
| RPS7 | ribosomal protein S7 | 0.0202674 |
| FAM168A | family with sequence similarity 168, member A | 0.0198939 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0198462 |
| ENO1 | enolase 1, (alpha) | 0.0197595 |
| THBS1 | thrombospondin 1 | 0.0188668 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0187886 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0186968 |
| YBX1 | Y box binding protein 1 | 0.0185675 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0184966 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0182547 |
| CALR | calreticulin | 0.0181455 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0179812 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0179807 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0178923 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0178489 |
| B2M | beta-2-microglobulin | 0.0174228 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0171784 |
| AREG | amphiregulin | 0.0168287 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0167816 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0167439 |
| PFKP | phosphofructokinase, platelet | 0.0166304 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0165409 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 0.0161504 |
| RPL7 | ribosomal protein L7 | 0.0160517 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.015832 |
| ANXA5 | annexin A5 | 0.0157632 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0157493 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0156377 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0156357 |
| RPS2 | ribosomal protein S2 | 0.0154465 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0154007 |
| AATF | apoptosis antagonizing transcription factor | 0.015386 |
| ASPH | aspartate beta-hydroxylase | 0.0151145 |
| TCIM | transcriptional and immune response regulator | 0.0150065 |
| ZNF410 | zinc finger protein 410 | 0.0149116 |
| RFWD3 | ring finger and WD repeat domain 3 | 0.0147846 |
| DEK | DEK proto-oncogene | 0.0147381 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.014732 |
| NRG1 | neuregulin 1 | 0.0147242 |
| CDC42 | cell division cycle 42 | 0.0145168 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.014471 |
| LAMB1 | laminin, beta 1 | 0.0143979 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0140006 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0137376 |
| MATR3 | matrin 3 | 0.0136116 |
| SET | SET nuclear proto-oncogene | 0.0134183 |
| HYOU1 | hypoxia up-regulated 1 | 0.0132961 |
| BMP6 | bone morphogenetic protein 6 | 0.0132682 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0132625 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0130786 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.013075 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.168267 |
| TMSB10 | thymosin beta 10 | -0.152369 |
| MT2A | metallothionein 2A | -0.147064 |
| VIM | vimentin | -0.109184 |
| IGF2 | insulin-like growth factor 2 | -0.107932 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.083038 |
| FTL | ferritin, light polypeptide | -0.0719312 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0690956 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0657177 |
| ACTG1 | actin gamma 1 | -0.0644482 |
| HDAC9 | histone deacetylase 9 | -0.0621068 |
| SVIL | supervillin | -0.0603982 |
| CMIP | c-Maf inducing protein | -0.0550557 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0548251 |
| FMNL2 | formin-like 2 | -0.0537091 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0493702 |
| PARD3 | par-3 family cell polarity regulator | -0.0492172 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0470307 |
| ERBIN | erbb2 interacting protein | -0.045544 |
| S100A6 | S100 calcium binding protein A6 | -0.0455089 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0441 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0438924 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0416423 |
| USP34 | ubiquitin specific peptidase 34 | -0.0410948 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0406309 |
| ZNF207 | zinc finger protein 207 | -0.0396896 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0384701 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.038142 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0367424 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0353982 |
| POTEF | POTE ankyrin domain family, member F | -0.0348415 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0342376 |
| PFN1 | profilin 1 | -0.0340898 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0336902 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0329742 |
| EGFR | epidermal growth factor receptor | -0.0328879 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.032783 |
| GLG1 | golgi glycoprotein 1 | -0.0327148 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0319058 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0315301 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0314635 |
| IER3 | immediate early response 3 | -0.0311241 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0311163 |
| FLNB | filamin B, beta | -0.0310769 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0307825 |
| RBM25 | RNA binding motif protein 25 | -0.0304426 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0299787 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0299098 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0297264 |
| JMJD1C | jumonji domain containing 1C | -0.0292501 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0290288 |
| SMAD2 | SMAD family member 2 | -0.0285211 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0284033 |
| NDRG1 | N-myc downstream regulated 1 | -0.0282878 |
| SBF2 | SET binding factor 2 | -0.0282314 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0278833 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.027823 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0277628 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0276947 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0276844 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0275324 |
| TPD52 | tumor protein D52 | -0.0273138 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0272772 |
| UTRN | utrophin | -0.0270165 |
| PKM | pyruvate kinase, muscle | -0.0269392 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0268618 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0264159 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0261308 |
| PHF20 | PHD finger protein 20 | -0.0260561 |
| ZFHX3 | zinc finger homeobox 3 | -0.0260072 |
| FAM107B | family with sequence similarity 107, member B | -0.0259675 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0258933 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0258212 |
| HMGA1 | high mobility group AT-hook 1 | -0.0253695 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0253561 |
| CUX1 | cut-like homeobox 1 | -0.0252427 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0250629 |
| SIK3 | SIK family kinase 3 | -0.0242616 |
| HLA-B | major histocompatibility complex, class I, B | -0.024198 |
| COPA | coatomer protein complex, subunit alpha | -0.0239432 |
| WAC | WW domain containing adaptor with coiled-coil | -0.023813 |
| NF1 | neurofibromin 1 | -0.0238125 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0234532 |
| AK1 | adenylate kinase 1 | -0.0233793 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0233138 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0233009 |
| YY1 | YY1 transcription factor | -0.0231657 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0228797 |
| RBM39 | RNA binding motif protein 39 | -0.0227952 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0227905 |
| DENND5B | DENN/MADD domain containing 5B | -0.0224976 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0224397 |
| INO80 | INO80 complex subunit | -0.0223933 |
| KYNU | kynureninase | -0.0223131 |
| EGR1 | early growth response 1 | -0.0220327 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0219857 |
| ACACA | acetyl-CoA carboxylase alpha | -0.021897 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0218597 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0218165 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0217652 |
