| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Finasteride perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Finasteride_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.152117 |
| PDE10A | phosphodiesterase 10A | 0.13565 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.123082 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0919405 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.089417 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0864387 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0853327 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.084724 |
| RPL23 | ribosomal protein L23 | 0.0824748 |
| B2M | beta-2-microglobulin | 0.0791785 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0790324 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.076613 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0746375 |
| KRT17 | keratin 17, type I | 0.0739123 |
| RABGAP1 | RAB GTPase activating protein 1 | 0.0716491 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0707121 |
| FMN1 | formin 1 | 0.0652324 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0618015 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0617182 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.060065 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.059534 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0582088 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0571146 |
| RPS24 | ribosomal protein S24 | 0.056576 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0550577 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0545497 |
| EGFR | epidermal growth factor receptor | 0.0544548 |
| NAV2 | neuron navigator 2 | 0.0541682 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0539613 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0532449 |
| GNAS | GNAS complex locus | 0.052778 |
| POTEF | POTE ankyrin domain family, member F | 0.0526298 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0519622 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.050317 |
| DSPP | dentin sialophosphoprotein | 0.0495245 |
| STK24 | serine/threonine kinase 24 | 0.0477394 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0475638 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0467352 |
| RPS6 | ribosomal protein S6 | 0.0464188 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.045464 |
| WDR43 | WD repeat domain 43 | 0.0447097 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0446977 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0434653 |
| TXNRD1 | thioredoxin reductase 1 | 0.0430185 |
| TOP1 | topoisomerase (DNA) I | 0.0424092 |
| LMO7 | LIM domain 7 | 0.0423508 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0422796 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0418519 |
| TPM3 | tropomyosin 3 | 0.0417783 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0415911 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0407257 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0406278 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0402033 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0400521 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0396723 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0394626 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0386261 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.03833 |
| H3-3B | H3.3 histone B | 0.0382233 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0382215 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0378281 |
| CBFB | core-binding factor, beta subunit | 0.0378245 |
| CCNL1 | cyclin L1 | 0.0370866 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0370782 |
| SP100 | SP100 nuclear antigen | 0.0370556 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0368095 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0366811 |
| MRTFA | myocardin related transcription factor A | 0.036064 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0357194 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0355159 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0352443 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0348882 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0346678 |
| KYNU | kynureninase | 0.0346129 |
| RPL12 | ribosomal protein L12 | 0.0344304 |
| MYO5B | myosin VB | 0.0343984 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.034336 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0341889 |
| RPL37A | ribosomal protein L37a | 0.0339324 |
| RPL31 | ribosomal protein L31 | 0.0337583 |
| FOXO3 | forkhead box O3 | 0.0337036 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0336431 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0331571 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0331209 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0328803 |
| IPO7 | importin 7 | 0.0326142 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0325848 |
| CDK6 | cyclin-dependent kinase 6 | 0.0325059 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0322134 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0321288 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0321155 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0315946 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0303543 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0298647 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0297861 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0292643 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0290739 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0286406 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0284988 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0281982 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.195861 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.160271 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.153154 |
| MYO1E | myosin IE | -0.138492 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.136778 |
| FN1 | fibronectin 1 | -0.126559 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.114755 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.105593 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.100545 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.09448 |
| INTS6 | integrator complex subunit 6 | -0.093359 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0896485 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0891251 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0872508 |
| AHNAK | AHNAK nucleoprotein | -0.0843607 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0811483 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0808174 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0802789 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0798541 |
| MMP1 | matrix metallopeptidase 1 | -0.0766851 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0759588 |
| LAMC2 | laminin, gamma 2 | -0.0756091 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.066384 |
| MT2A | metallothionein 2A | -0.066016 |
| ATOSA | atos homolog A | -0.065681 |
| GPC6 | glypican 6 | -0.0655232 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0654784 |
| PARD3 | par-3 family cell polarity regulator | -0.0652421 |
| GLIS3 | GLIS family zinc finger 3 | -0.0639905 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0637079 |
| RBM47 | RNA binding motif protein 47 | -0.0636093 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0632039 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0609892 |
| IGF2 | insulin-like growth factor 2 | -0.0595096 |
| FTL | ferritin, light polypeptide | -0.0594186 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0566176 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.0563554 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0563033 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0562544 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.056082 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0554697 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0549461 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0543546 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0536882 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0523046 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0521987 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0502022 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0501046 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0493828 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0489554 |
| HMGA2 | high mobility group AT-hook 2 | -0.0486389 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0482182 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0472974 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0471343 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0458868 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0453231 |
| FBXO11 | F-box protein 11 | -0.0452522 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0441867 |
| SMAD3 | SMAD family member 3 | -0.0441782 |
| RORA | RAR-related orphan receptor A | -0.0431682 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0425042 |
| FRMD5 | FERM domain containing 5 | -0.0418635 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0417707 |
| DENND4A | DENN/MADD domain containing 4A | -0.0410575 |
| CD44 | CD44 molecule (Indian blood group) | -0.0404788 |
| FMNL2 | formin-like 2 | -0.0393967 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0393782 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0389374 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0389287 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0385783 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.038543 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0384562 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0383305 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0378736 |
| ABHD17C | abhydrolase domain containing 17C | -0.0376353 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0364826 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.036436 |
| FNIP1 | folliculin interacting protein 1 | -0.0362509 |
| MXD1 | MAX dimerization protein 1 | -0.035085 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0337345 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0323172 |
| PRKCA | protein kinase C, alpha | -0.032124 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0310804 |
| EFNA5 | ephrin-A5 | -0.0308387 |
| ATP13A3 | ATPase type 13A3 | -0.0304511 |
| LMNA | lamin A/C | -0.0304086 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0297192 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0295557 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0294706 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0294544 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0289315 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0288566 |
| CD109 | CD109 molecule | -0.0284548 |
| LOXL2 | lysyl oxidase-like 2 | -0.0280589 |
| ASPH | aspartate beta-hydroxylase | -0.0271411 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0271224 |
| SEPTIN2 | septin 2 | -0.0266178 |
| CCND1 | cyclin D1 | -0.0262889 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0252772 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0249833 |
