| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Finasteride perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Finasteride_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.226209 |
| FN1 | fibronectin 1 | 0.180849 |
| GRB10 | growth factor receptor-bound protein 10 | 0.172283 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.144439 |
| VEGFA | vascular endothelial growth factor A | 0.143575 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.121978 |
| CALR | calreticulin | 0.120436 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.110123 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.109978 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.106988 |
| ENO1 | enolase 1, (alpha) | 0.0938986 |
| LAMB3 | laminin, beta 3 | 0.0915895 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0890492 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0849984 |
| KRT7 | keratin 7, type II | 0.0817186 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0813775 |
| ANXA2 | annexin A2 | 0.0785051 |
| TOP1 | topoisomerase (DNA) I | 0.0780484 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0769958 |
| TMSB4X | thymosin beta 4, X-linked | 0.0704277 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0684963 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.06722 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.066918 |
| RHOA | ras homolog family member A | 0.066907 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.065274 |
| PLAU | plasminogen activator, urokinase | 0.0651927 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0629983 |
| CANX | calnexin | 0.0620218 |
| AHNAK | AHNAK nucleoprotein | 0.0618141 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0610095 |
| RNF145 | ring finger protein 145 | 0.0603144 |
| G0S2 | G0/G1 switch 2 | 0.0572381 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0556592 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0543236 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0525255 |
| KRT18 | keratin 18, type I | 0.0525079 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0521604 |
| FAM13A | family with sequence similarity 13, member A | 0.0506737 |
| PTMA | prothymosin, alpha | 0.0505768 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0493452 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0482362 |
| CCNL1 | cyclin L1 | 0.0455614 |
| RPS3 | ribosomal protein S3 | 0.0452473 |
| RPL35A | ribosomal protein L35a | 0.0452079 |
| ARRDC3 | arrestin domain containing 3 | 0.0447655 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0439528 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0432254 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0428456 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0427062 |
| CTSB | cathepsin B | 0.0421649 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.041676 |
| MATR3 | matrin 3 | 0.0411694 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0409656 |
| DSPP | dentin sialophosphoprotein | 0.0396632 |
| PTK2 | protein tyrosine kinase 2 | 0.039561 |
| IRF6 | interferon regulatory factor 6 | 0.0395503 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0395465 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0392168 |
| PGK1 | phosphoglycerate kinase 1 | 0.0386238 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0381659 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0381547 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0378169 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0375613 |
| RAD21 | RAD21 homolog (S. pombe) | 0.037506 |
| YBX1 | Y box binding protein 1 | 0.0374276 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0372162 |
| CD47 | CD47 molecule | 0.0369628 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0364738 |
| TMSB10 | thymosin beta 10 | 0.0363399 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.035816 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0356878 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.035596 |
| COPA | coatomer protein complex, subunit alpha | 0.0354315 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0349969 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0347964 |
| MSI2 | musashi RNA-binding protein 2 | 0.0343036 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0340763 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0338963 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0338448 |
| B2M | beta-2-microglobulin | 0.0337841 |
| TPI1 | triosephosphate isomerase 1 | 0.0335027 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0333429 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0332195 |
| CCND1 | cyclin D1 | 0.0330468 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.032801 |
| NAV2 | neuron navigator 2 | 0.032751 |
| KRT8 | keratin 8, type II | 0.0326801 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0324551 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0317397 |
| RACK1 | receptor for activated C kinase 1 | 0.0312356 |
| F11R | F11 receptor | 0.03008 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0299036 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0297148 |
| RPL23 | ribosomal protein L23 | 0.0296939 |
| PLEC | plectin | 0.0286531 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0285679 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0281032 |
| CLIC1 | chloride intracellular channel 1 | 0.0280585 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0276809 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0273794 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.175173 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.168561 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.162099 |
| ACTG1 | actin gamma 1 | -0.100052 |
| NDRG1 | N-myc downstream regulated 1 | -0.0787374 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0604312 |
| RPS2 | ribosomal protein S2 | -0.054608 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0508813 |
| SDC4 | syndecan 4 | -0.0468988 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0458172 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0455878 |
| GOLGA4 | golgin A4 | -0.0455205 |
| FBXO32 | F-box protein 32 | -0.0435834 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0425553 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0418081 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0412921 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0387751 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0385279 |
| POTEF | POTE ankyrin domain family, member F | -0.036019 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0359956 |
| GOLT1B | golgi transport 1B | -0.03566 |
| S100A6 | S100 calcium binding protein A6 | -0.035383 |
| RPS13 | ribosomal protein S13 | -0.0341604 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0333361 |
| BRD2 | bromodomain containing 2 | -0.0316662 |
| DSG2 | desmoglein 2 | -0.0306846 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0306572 |
| CEP350 | centrosomal protein 350kDa | -0.0306072 |
| RPL27A | ribosomal protein L27a | -0.0302617 |
| RPL38 | ribosomal protein L38 | -0.0300661 |
| RPL19 | ribosomal protein L19 | -0.0296053 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0282104 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.027921 |
| TXNIP | thioredoxin interacting protein | -0.0277307 |
| CDCP1 | CUB domain containing protein 1 | -0.0274178 |
| MYO1E | myosin IE | -0.0265564 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0261581 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | -0.0261305 |
| FTL | ferritin, light polypeptide | -0.026089 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0257246 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.025614 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0255771 |
| RYBP | RING1 and YY1 binding protein | -0.0255021 |
| CLTC | clathrin, heavy chain (Hc) | -0.0254484 |
| DTNA | dystrobrevin, alpha | -0.0247695 |
| RPL15 | ribosomal protein L15 | -0.0245766 |
| TXNRD1 | thioredoxin reductase 1 | -0.0244629 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0243117 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0242468 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0238886 |
| ERBIN | erbb2 interacting protein | -0.0238389 |
| RPL9 | ribosomal protein L9 | -0.0233053 |
| RPLP2 | ribosomal protein, large, P2 | -0.0231674 |
| UBC | ubiquitin C | -0.0231433 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0228491 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0227473 |
| MYO10 | myosin X | -0.022535 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0223098 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0221604 |
| PLSCR1 | phospholipid scramblase 1 | -0.0220964 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0220896 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0216717 |
| PALLD | palladin, cytoskeletal associated protein | -0.0215399 |
| RPL7 | ribosomal protein L7 | -0.0214781 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0212548 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0209955 |
| ANO6 | anoctamin 6 | -0.0208572 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.020732 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0206767 |
| SACK1B | scaffolding CK1 anchoring protein B | -0.0205847 |
| CDK13 | cyclin-dependent kinase 13 | -0.0204291 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0203756 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0203607 |
| NUMB | numb homolog (Drosophila) | -0.0203227 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0201848 |
| RPS8 | ribosomal protein S8 | -0.0200471 |
| IFI44L | interferon-induced protein 44-like | -0.0197348 |
| GPHN | gephyrin | -0.019717 |
| RPL32 | ribosomal protein L32 | -0.019686 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.0196445 |
| RPL6 | ribosomal protein L6 | -0.0194896 |
| ATXN1 | ataxin 1 | -0.0194646 |
| SNX6 | sorting nexin 6 | -0.01939 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0192512 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0191654 |
| OCLN | occludin | -0.0189985 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -0.018956 |
| NUP98 | nucleoporin 98kDa | -0.0187492 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0187054 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.018635 |
| RAB10 | RAB10, member RAS oncogene family | -0.0185041 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0184648 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0183991 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0183954 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0181057 |
| JMJD1C | jumonji domain containing 1C | -0.0180689 |
| MT2A | metallothionein 2A | -0.0180132 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0179359 |
| HSPA8 | heat shock 70kDa protein 8 | -0.017868 |
| H1-4 | H1.4 linker histone, cluster member | -0.0178636 |
