| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Finasteride perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Finasteride_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.132032 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.106202 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0990097 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0968989 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0915946 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0856094 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0771736 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0757169 |
| FNDC3B | fibronectin type III domain containing 3B | 0.068623 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0666629 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0640656 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0632625 |
| MCL1 | myeloid cell leukemia 1 | 0.0631151 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0566182 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0562999 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0559071 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0551909 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0551551 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0540068 |
| SPAG9 | sperm associated antigen 9 | 0.0539927 |
| CANX | calnexin | 0.0521843 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0505225 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0503182 |
| WDR43 | WD repeat domain 43 | 0.0502063 |
| GOLGA4 | golgin A4 | 0.0499853 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0497253 |
| TPM3 | tropomyosin 3 | 0.0483232 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0470343 |
| DNER | delta/notch-like EGF repeat containing | 0.0465818 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0460812 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0460165 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.045376 |
| ANKRD11 | ankyrin repeat domain 11 | 0.045243 |
| B2M | beta-2-microglobulin | 0.0449667 |
| MSN | moesin | 0.0448589 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0432941 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0430876 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0427417 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0424377 |
| NUP58 | nucleoporin 58 | 0.0421347 |
| CTBP2 | C-terminal binding protein 2 | 0.0421298 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0418434 |
| ENO1 | enolase 1, (alpha) | 0.0414623 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0410517 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0410049 |
| FAM13A | family with sequence similarity 13, member A | 0.0403558 |
| RPL26 | ribosomal protein L26 | 0.0402656 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0400247 |
| SUCO | SUN domain containing ossification factor | 0.0399186 |
| NBAS | neuroblastoma amplified sequence | 0.0399039 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0395606 |
| FLNB | filamin B, beta | 0.0394236 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0389817 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0385811 |
| RTN4 | reticulon 4 | 0.0384055 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0383853 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0383475 |
| MATR3 | matrin 3 | 0.038223 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0381275 |
| RPL3 | ribosomal protein L3 | 0.0378994 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0368463 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0358946 |
| STC1 | stanniocalcin 1 | 0.0355362 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0354754 |
| PCBP2 | poly(rC) binding protein 2 | 0.0352178 |
| EFNA5 | ephrin-A5 | 0.0351896 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0349493 |
| HELZ | helicase with zinc finger | 0.0349057 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0347138 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0346747 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0343445 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0342328 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0342205 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0340979 |
| COPA | coatomer protein complex, subunit alpha | 0.0340603 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0340113 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0340016 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.033394 |
| RNF145 | ring finger protein 145 | 0.0332117 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0331851 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0329849 |
| RPS18 | ribosomal protein S18 | 0.0327006 |
| ATP13A3 | ATPase type 13A3 | 0.0323826 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0321697 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0320581 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0319208 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0316036 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0312166 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0311632 |
| UBC | ubiquitin C | 0.0310453 |
| FLNA | filamin A, alpha | 0.0309731 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0309186 |
| RHOA | ras homolog family member A | 0.030751 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0306715 |
| USP34 | ubiquitin specific peptidase 34 | 0.0306707 |
| FMNL2 | formin-like 2 | 0.0303823 |
| ZNF292 | zinc finger protein 292 | 0.0303649 |
| CLTC | clathrin, heavy chain (Hc) | 0.0302809 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0302676 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0300743 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.219557 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.131236 |
| TMSB10 | thymosin beta 10 | -0.119297 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0970159 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0628027 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0542146 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0524551 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0511345 |
| RPS24 | ribosomal protein S24 | -0.0492008 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0438417 |
| RPLP1 | ribosomal protein, large, P1 | -0.0418513 |
| GNAS | GNAS complex locus | -0.0416379 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0407275 |
| COL5A2 | collagen, type V, alpha 2 | -0.0396272 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0388242 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0378065 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0371304 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0363746 |
| PDLIM5 | PDZ and LIM domain 5 | -0.036254 |
| MT2A | metallothionein 2A | -0.0357648 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0343464 |
| RPL35A | ribosomal protein L35a | -0.0343202 |
| GDA | guanine deaminase | -0.0325736 |
| FTL | ferritin, light polypeptide | -0.0319162 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0304619 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0278624 |
| RPS19 | ribosomal protein S19 | -0.0264214 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0262497 |
| RPL31 | ribosomal protein L31 | -0.0260204 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0255662 |
| RPL36 | ribosomal protein L36 | -0.025498 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0252245 |
| RPL34 | ribosomal protein L34 | -0.0251003 |
| COL4A5 | collagen, type IV, alpha 5 | -0.024788 |
| RPLP2 | ribosomal protein, large, P2 | -0.0244659 |
| RPL9 | ribosomal protein L9 | -0.0243618 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0241674 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0236498 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0235702 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.0231864 |
| RPL23 | ribosomal protein L23 | -0.0230763 |
| RTN1 | reticulon 1 | -0.0226862 |
| RPL38 | ribosomal protein L38 | -0.0226429 |
| PALLD | palladin, cytoskeletal associated protein | -0.0219053 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0215933 |
| SMYD3 | SET and MYND domain containing 3 | -0.0213899 |
| EGR1 | early growth response 1 | -0.0211124 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0204119 |
| SMAD2 | SMAD family member 2 | -0.0202957 |
| ASPH | aspartate beta-hydroxylase | -0.0202273 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0202048 |
| RPS8 | ribosomal protein S8 | -0.019828 |
| RPL19 | ribosomal protein L19 | -0.0196381 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.019501 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0194761 |
| RPS29 | ribosomal protein S29 | -0.0194173 |
| S100A6 | S100 calcium binding protein A6 | -0.0193321 |
| RPS21 | ribosomal protein S21 | -0.0192463 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | -0.0191785 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0190461 |
| SRGN | serglycin | -0.018962 |
| BPTF | bromodomain PHD finger transcription factor | -0.0187856 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0187485 |
| RPL36A | ribosomal protein L36a | -0.0185892 |
| PRKD3 | protein kinase D3 | -0.0183293 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.01819 |
| S100A10 | S100 calcium binding protein A10 | -0.0180265 |
| OSMR | oncostatin M receptor | -0.0178601 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0178278 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0178228 |
| NTN4 | netrin 4 | -0.0177101 |
| ALPK2 | alpha-kinase 2 | -0.0174584 |
| PDE1A | phosphodiesterase 1A, calmodulin-dependent | -0.0172592 |
| YBX3 | Y box binding protein 3 | -0.0171946 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0171409 |
| RHOB | ras homolog family member B | -0.0171106 |
| ATXN1 | ataxin 1 | -0.0171052 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0170795 |
| RPL32 | ribosomal protein L32 | -0.016971 |
| CD109 | CD109 molecule | -0.0169616 |
| HLA-B | major histocompatibility complex, class I, B | -0.0167145 |
| KYNU | kynureninase | -0.015914 |
| HMGB1 | high mobility group box 1 | -0.0158807 |
| VIM | vimentin | -0.0156058 |
| KIAA0825 | KIAA0825 | -0.0154338 |
| RPS27A | ribosomal protein S27a | -0.0153582 |
| TBC1D19 | TBC1 domain family, member 19 | -0.0150929 |
| RPS28 | ribosomal protein S28 | -0.0150777 |
| RPS27 | ribosomal protein S27 | -0.0150386 |
| TENM3 | teneurin transmembrane protein 3 | -0.0148722 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0148088 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0144861 |
| RPS25 | ribosomal protein S25 | -0.0144837 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.014426 |
| RPL37A | ribosomal protein L37a | -0.0142958 |
| PTMA | prothymosin, alpha | -0.0141385 |
| TRIM56 | tripartite motif containing 56 | -0.0140631 |
| RPL13A | ribosomal protein L13a | -0.0140518 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0136392 |
| EPHA4 | EPH receptor A4 | -0.0135054 |
