| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Finasteride perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Finasteride_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.2217 |
| TMSB4X | thymosin beta 4, X-linked | 0.128032 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.113325 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.102627 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.100144 |
| EZR | ezrin | 0.0974185 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0942848 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.082251 |
| ENO1 | enolase 1, (alpha) | 0.0750233 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0737854 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0686749 |
| FLNB | filamin B, beta | 0.0673675 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0671582 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0657798 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0573246 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0563507 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0558928 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0558666 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0557948 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0539535 |
| RPL3 | ribosomal protein L3 | 0.0536269 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0531013 |
| AHNAK | AHNAK nucleoprotein | 0.052138 |
| RHOA | ras homolog family member A | 0.0505937 |
| PDGFC | platelet derived growth factor C | 0.0503956 |
| SBF2 | SET binding factor 2 | 0.0502141 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0500695 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0499735 |
| PRELID2 | PRELI domain containing 2 | 0.0497638 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0496222 |
| MKI67 | marker of proliferation Ki-67 | 0.049268 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0492499 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0488177 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0480769 |
| ANXA1 | annexin A1 | 0.0470862 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0470386 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0461532 |
| FAT1 | FAT atypical cadherin 1 | 0.0460285 |
| RPL26 | ribosomal protein L26 | 0.0459486 |
| BMP10 | bone morphogenetic protein 10 | 0.0453998 |
| ZNF292 | zinc finger protein 292 | 0.0453615 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0453079 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0435015 |
| ECT2 | epithelial cell transforming 2 | 0.0417988 |
| CD47 | CD47 molecule | 0.0417749 |
| BMP2K | BMP2 inducible kinase | 0.0410836 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0397198 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0392502 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0392204 |
| BRD2 | bromodomain containing 2 | 0.0390161 |
| YAP1 | Yes-associated protein 1 | 0.0388825 |
| EVI5 | ecotropic viral integration site 5 | 0.0383593 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0376801 |
| RPS18 | ribosomal protein S18 | 0.0373531 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0359672 |
| DIAPH3 | diaphanous-related formin 3 | 0.0358915 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0353392 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0353045 |
| RAD18 | RAD18 E3 ubiquitin protein ligase | 0.0349469 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0345562 |
| DENND1A | DENN/MADD domain containing 1A | 0.0343384 |
| RPS6 | ribosomal protein S6 | 0.0334351 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0332693 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0331614 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.032862 |
| APP | amyloid beta (A4) precursor protein | 0.0327601 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0326515 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0326189 |
| MYOF | myoferlin | 0.0323961 |
| AMOTL2 | angiomotin like 2 | 0.0322947 |
| UNC13A | unc-13 homolog A (C. elegans) | 0.0315607 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0307884 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.030473 |
| FAM13A | family with sequence similarity 13, member A | 0.0302843 |
| GLI2 | GLI family zinc finger 2 | 0.0302254 |
| GOLGA4 | golgin A4 | 0.0301826 |
| CENPF | centromere protein F, 350/400kDa | 0.0300512 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0299755 |
| HJURP | Holliday junction recognition protein | 0.029833 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0298239 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0292036 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0290268 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0289424 |
| MATR3 | matrin 3 | 0.0286784 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0283407 |
| ANLN | anillin, actin binding protein | 0.0283278 |
| SET | SET nuclear proto-oncogene | 0.0282889 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0274271 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0273729 |
| HDAC9 | histone deacetylase 9 | 0.0272988 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0272932 |
| MSI2 | musashi RNA-binding protein 2 | 0.0270573 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0269076 |
| PTK2 | protein tyrosine kinase 2 | 0.026721 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0263202 |
| SMYD3 | SET and MYND domain containing 3 | 0.026095 |
| TJP1 | tight junction protein 1 | 0.0260374 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0259891 |
| MYO5C | myosin VC | 0.025466 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.025317 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.135291 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0775238 |
| S100A6 | S100 calcium binding protein A6 | -0.0700783 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0542871 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0507493 |
| ACTG1 | actin gamma 1 | -0.0456773 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0372684 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0371858 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0367167 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0361219 |
| PFN1 | profilin 1 | -0.0340747 |
| ANK2 | ankyrin 2, neuronal | -0.0316069 |
| RPLP0 | ribosomal protein, large, P0 | -0.0314972 |
| RIGI | RNA sensor RIG-I | -0.0312741 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0300265 |
| DUSP6 | dual specificity phosphatase 6 | -0.0299994 |
| GNAS | GNAS complex locus | -0.0298134 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0297057 |
| FTL | ferritin, light polypeptide | -0.0296943 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.029594 |
| S100A4 | S100 calcium binding protein A4 | -0.0295234 |
| HLA-B | major histocompatibility complex, class I, B | -0.0293638 |
| TXNRD1 | thioredoxin reductase 1 | -0.0284974 |
| RPL35A | ribosomal protein L35a | -0.0277848 |
| OSMR | oncostatin M receptor | -0.0276525 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0273657 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0265785 |
| NF1 | neurofibromin 1 | -0.0254424 |
| CCNI | cyclin I | -0.0239362 |
| PRDX2 | peroxiredoxin 2 | -0.0238778 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0229297 |
| RBM39 | RNA binding motif protein 39 | -0.0228378 |
| RPL27A | ribosomal protein L27a | -0.0227227 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0221232 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0221028 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0220038 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0219831 |
| RPS24 | ribosomal protein S24 | -0.0218782 |
| MT2A | metallothionein 2A | -0.021619 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0215792 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0212733 |
| TMEM263 | transmembrane protein 263 | -0.0206369 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.01971 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0193667 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0189251 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0186883 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0185731 |
| RPLP1 | ribosomal protein, large, P1 | -0.0177791 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0176123 |
| RPL36A | ribosomal protein L36a | -0.0175494 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0172807 |
| RPL13A | ribosomal protein L13a | -0.0170215 |
| RPLP2 | ribosomal protein, large, P2 | -0.0168983 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0164855 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0162158 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0161519 |
| RPL34 | ribosomal protein L34 | -0.016083 |
| PLSCR1 | phospholipid scramblase 1 | -0.0160376 |
| RPS11 | ribosomal protein S11 | -0.0160201 |
| CAPN7 | calpain 7 | -0.0158871 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0158451 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0158088 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0156538 |
| RPS21 | ribosomal protein S21 | -0.0154756 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0153867 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | -0.0149736 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0149522 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.0148352 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.0147608 |
| ETV5 | ets variant 5 | -0.0146778 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0146246 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0146091 |
| HLA-E | major histocompatibility complex, class I, E | -0.0145468 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0144887 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0144878 |
| TAPBP | TAP binding protein (tapasin) | -0.0144621 |
| TMEM123 | transmembrane protein 123 | -0.0144309 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0143381 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0143078 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0143017 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | -0.0142964 |
| PHF14 | PHD finger protein 14 | -0.0142551 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0142316 |
| ETV6 | ets variant 6 | -0.0142315 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0142066 |
| CFAP73 | cilia and flagella associated protein 73 | -0.0140519 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0139734 |
| ZNF207 | zinc finger protein 207 | -0.013925 |
| TRIM56 | tripartite motif containing 56 | -0.0139102 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0137927 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0137763 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0136286 |
| MTAP | methylthioadenosine phosphorylase | -0.0135714 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0135701 |
| TMSB10 | thymosin beta 10 | -0.0135619 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0135537 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0133983 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.0133692 |
| FAM193A | family with sequence similarity 193, member A | -0.0133638 |
| R3HDM1 | R3H domain containing 1 | -0.0131532 |
