| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Finasteride perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Finasteride_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.280155 |
| FN1 | fibronectin 1 | 0.128982 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.110825 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.108102 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.105318 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0972613 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0916366 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.078654 |
| ZNF292 | zinc finger protein 292 | 0.0765809 |
| NAV2 | neuron navigator 2 | 0.075481 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0740373 |
| GOLGA4 | golgin A4 | 0.0728879 |
| VEGFA | vascular endothelial growth factor A | 0.0722446 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.071929 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0717449 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0689551 |
| SPAG9 | sperm associated antigen 9 | 0.0686301 |
| OGA | O-GlcNAcase | 0.0656366 |
| HELZ | helicase with zinc finger | 0.0634558 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0625253 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0614547 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0609368 |
| MSN | moesin | 0.0599364 |
| MATR3 | matrin 3 | 0.0585895 |
| ANXA2 | annexin A2 | 0.0585202 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0566427 |
| CENPF | centromere protein F, 350/400kDa | 0.0554062 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0552392 |
| ANLN | anillin, actin binding protein | 0.0536987 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0524514 |
| B2M | beta-2-microglobulin | 0.0522029 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0520899 |
| FLNA | filamin A, alpha | 0.0513378 |
| CALR | calreticulin | 0.0508112 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.050201 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0500821 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0498333 |
| ATP13A3 | ATPase type 13A3 | 0.0483512 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0481086 |
| SFTPA2 | surfactant protein A2 | 0.0477016 |
| RBM39 | RNA binding motif protein 39 | 0.0468786 |
| DST | dystonin | 0.046209 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0461126 |
| RPL26 | ribosomal protein L26 | 0.0457853 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.045626 |
| ARRDC3 | arrestin domain containing 3 | 0.0453986 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0449691 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0444679 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0437308 |
| TEX10 | testis expressed 10 | 0.0434437 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0430482 |
| APP | amyloid beta (A4) precursor protein | 0.0422572 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0421808 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0421749 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0418635 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0418058 |
| MYOF | myoferlin | 0.0411131 |
| PCBP2 | poly(rC) binding protein 2 | 0.0389875 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0389775 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0388482 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.038674 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0385093 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0384648 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0382738 |
| DEK | DEK proto-oncogene | 0.0381121 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0380138 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0378015 |
| PGK1 | phosphoglycerate kinase 1 | 0.0377496 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0376389 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0372881 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0368696 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.036762 |
| RPL11 | ribosomal protein L11 | 0.0367407 |
| POTEF | POTE ankyrin domain family, member F | 0.0365416 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.036461 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0358641 |
| CLTC | clathrin, heavy chain (Hc) | 0.0358223 |
| SRGN | serglycin | 0.0358214 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0357088 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0350616 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0350287 |
| FNIP1 | folliculin interacting protein 1 | 0.0348908 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0347199 |
| RPS18 | ribosomal protein S18 | 0.0343056 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0342612 |
| TMSB4X | thymosin beta 4, X-linked | 0.0338713 |
| FOXO3 | forkhead box O3 | 0.0338683 |
| CCNL1 | cyclin L1 | 0.0337901 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0335932 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.033406 |
| CEP250 | centrosomal protein 250kDa | 0.0332733 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.033058 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0329274 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0326998 |
| TXNRD1 | thioredoxin reductase 1 | 0.0325032 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0324451 |
| JMJD1C | jumonji domain containing 1C | 0.0323692 |
| PDE10A | phosphodiesterase 10A | 0.032179 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0319951 |
| DSTN | destrin (actin depolymerizing factor) | 0.0318809 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0914235 |
| VIM | vimentin | -0.0893651 |
| GLIS3 | GLIS family zinc finger 3 | -0.0836621 |
| BICC1 | BicC family RNA binding protein 1 | -0.0751029 |
| FRMD4A | FERM domain containing 4A | -0.073762 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0703471 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0636073 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0606592 |
| HMGA2 | high mobility group AT-hook 2 | -0.059433 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.056168 |
| IER3 | immediate early response 3 | -0.0557083 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0532591 |
| EXT1 | exostosin glycosyltransferase 1 | -0.051255 |
| VCL | vinculin | -0.0492631 |
| EGR1 | early growth response 1 | -0.0492445 |
| RAI14 | retinoic acid induced 14 | -0.0474885 |
| FTL | ferritin, light polypeptide | -0.0420542 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0420379 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.04122 |
| KYNU | kynureninase | -0.0406333 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0400124 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0399335 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.039652 |
| TMSB10 | thymosin beta 10 | -0.0389469 |
| TNS3 | tensin 3 | -0.0382401 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0370115 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0368908 |
| DIAPH2 | diaphanous-related formin 2 | -0.036658 |
| EGFR | epidermal growth factor receptor | -0.0360462 |
| C3 | complement component 3 | -0.0344891 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.033524 |
| RNF213 | ring finger protein 213 | -0.033043 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0324038 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0316621 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0315563 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0288044 |
| LOX | lysyl oxidase | -0.0286801 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0285109 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0280872 |
| NABP1 | nucleic acid binding protein 1 | -0.0273256 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0267337 |
| HDAC9 | histone deacetylase 9 | -0.0264212 |
| EFNA5 | ephrin-A5 | -0.0261647 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0261193 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.026063 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0258802 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0256258 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0255462 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0242367 |
| CTSD | cathepsin D | -0.0241078 |
| NAV1 | neuron navigator 1 | -0.0239911 |
| CLMP | CXADR-like membrane protein | -0.0238307 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0235527 |
| HLA-B | major histocompatibility complex, class I, B | -0.0232951 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0229029 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0228215 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.022813 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0226583 |
| FOXP1 | forkhead box P1 | -0.0224317 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0223938 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0221286 |
| IL6 | interleukin 6 | -0.0220352 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0219867 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0219107 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.021909 |
| PALLD | palladin, cytoskeletal associated protein | -0.0218005 |
| NDRG1 | N-myc downstream regulated 1 | -0.0213877 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0213015 |
| NRP1 | neuropilin 1 | -0.0209503 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0205214 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.019807 |
| EHBP1 | EH domain binding protein 1 | -0.0196164 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0194993 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0193769 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.019351 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0193415 |
| RGS17 | regulator of G-protein signaling 17 | -0.0192195 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0189476 |
| MT2A | metallothionein 2A | -0.0187803 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0186456 |
| SH3PXD2B | SH3 and PX domains 2B | -0.0184913 |
| HLA-E | major histocompatibility complex, class I, E | -0.0182946 |
| TMEM132D | transmembrane protein 132D | -0.0182832 |
| OSMR | oncostatin M receptor | -0.0179216 |
| FAM20C | family with sequence similarity 20, member C | -0.0176822 |
| INHBA | inhibin, beta A | -0.0173935 |
| KRT19 | keratin 19, type I | -0.0173198 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0170925 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0170794 |
| RAD51B | RAD51 paralog B | -0.0170593 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0170007 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0168741 |
| RIGI | RNA sensor RIG-I | -0.0167672 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0167206 |
| ETV6 | ets variant 6 | -0.0167144 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0165224 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0164228 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0164117 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0163445 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0163124 |
