| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Finasteride perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Finasteride_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.140441 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0922678 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.079244 |
| ANXA2 | annexin A2 | 0.0740356 |
| CEP250 | centrosomal protein 250kDa | 0.0690568 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0635619 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0629377 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0599591 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0576658 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0560301 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0556618 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0542858 |
| TPI1 | triosephosphate isomerase 1 | 0.0515064 |
| SETD5 | SET domain containing 5 | 0.0508522 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0484042 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0483829 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0481753 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0461795 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0461185 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0457827 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0430254 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0420888 |
| SEC24A | SEC24 family member A | 0.041751 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0414134 |
| CEP295 | centrosomal protein 295kDa | 0.0413842 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0406611 |
| AFDN | afadin, adherens junction formation factor | 0.0394946 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0394872 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.039107 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0390998 |
| MAP1B | microtubule-associated protein 1B | 0.0383889 |
| RNF216 | ring finger protein 216 | 0.0380616 |
| VIM | vimentin | 0.037889 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0378566 |
| ARRDC3 | arrestin domain containing 3 | 0.0378097 |
| ZFR | zinc finger RNA binding protein | 0.0377645 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0373327 |
| PKM | pyruvate kinase, muscle | 0.0369811 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0368355 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0367741 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.036172 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0358204 |
| UIMC1 | ubiquitin interaction motif containing 1 | 0.035647 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.035615 |
| WDR43 | WD repeat domain 43 | 0.0349861 |
| PDE8A | phosphodiesterase 8A | 0.0347019 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0343639 |
| FAM193A | family with sequence similarity 193, member A | 0.03431 |
| NPTN | neuroplastin | 0.0342011 |
| CANX | calnexin | 0.0340876 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0340828 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0340051 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0334045 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0330375 |
| RACK1 | receptor for activated C kinase 1 | 0.0330308 |
| RNF213 | ring finger protein 213 | 0.0328119 |
| PARD3 | par-3 family cell polarity regulator | 0.0326441 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.032402 |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 0.0321793 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.032013 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0319776 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0317614 |
| ARF4 | ADP-ribosylation factor 4 | 0.0316658 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0312264 |
| RNF111 | ring finger protein 111 | 0.031185 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0309347 |
| VMP1 | vacuole membrane protein 1 | 0.0307265 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0307253 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0305813 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0305808 |
| RSF1 | remodeling and spacing factor 1 | 0.0304945 |
| TUBB | tubulin, beta class I | 0.030286 |
| ENO1 | enolase 1, (alpha) | 0.0301718 |
| CLIC4 | chloride intracellular channel 4 | 0.0299706 |
| KIAA1958 | KIAA1958 | 0.0298422 |
| SEC13 | SEC13 homolog (S. cerevisiae) | 0.029668 |
| SNX9 | sorting nexin 9 | 0.0292254 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.0290889 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0290395 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0290167 |
| CD47 | CD47 molecule | 0.0286626 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0286092 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0285748 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0283888 |
| AHNAK | AHNAK nucleoprotein | 0.0283647 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0282623 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0282106 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0280134 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0278727 |
| COPA | coatomer protein complex, subunit alpha | 0.0276982 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0276575 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0276189 |
| STAG3 | stromal antigen 3 | 0.0275706 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0274964 |
| KLHDC10 | kelch domain containing 10 | 0.0274731 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0272192 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0269979 |
| RPS6 | ribosomal protein S6 | 0.0269699 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0269645 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0269323 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.188465 |
| YBX3 | Y box binding protein 3 | -0.0834343 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0827614 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0720491 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0672917 |
| ATM | ATM serine/threonine kinase | -0.062478 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0571015 |
| DST | dystonin | -0.0536661 |
| RIGI | RNA sensor RIG-I | -0.052152 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0515335 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0495391 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0491505 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0491034 |
| CPNE1 | copine I | -0.0488888 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0481791 |
| TPX2 | TPX2, microtubule-associated | -0.0477722 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | -0.0465194 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0463207 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0438329 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0437836 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0431491 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0423294 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0406362 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0403751 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0390124 |
| IGF2 | insulin-like growth factor 2 | -0.0384064 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0380651 |
| RPL38 | ribosomal protein L38 | -0.0374093 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0372167 |
| FNIP1 | folliculin interacting protein 1 | -0.0354926 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0347563 |
| CEP57 | centrosomal protein 57kDa | -0.0343512 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0341489 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0340342 |
| R3HDM1 | R3H domain containing 1 | -0.0336688 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.033312 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0331712 |
| SDC4 | syndecan 4 | -0.0329578 |
| CENPF | centromere protein F, 350/400kDa | -0.0326366 |
| SSH2 | slingshot protein phosphatase 2 | -0.0322269 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0318686 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0318145 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0314019 |
| CCNH | cyclin H | -0.0309758 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.030921 |
| FAM13B | family with sequence similarity 13, member B | -0.0308611 |
| PRR16 | proline rich 16 | -0.0307677 |
| OSBPL6 | oxysterol binding protein-like 6 | -0.030756 |
| ERBIN | erbb2 interacting protein | -0.0306414 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0301794 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0301021 |
| FN1 | fibronectin 1 | -0.0299601 |
| ADIPOR2 | adiponectin receptor 2 | -0.0299436 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0297789 |
| SPAG9 | sperm associated antigen 9 | -0.0296876 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0295755 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0294922 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0289292 |
| SQSTM1 | sequestosome 1 | -0.028726 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0287032 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0286486 |
| TMEM123 | transmembrane protein 123 | -0.0285985 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0284367 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0283034 |
| GPHN | gephyrin | -0.0282583 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | -0.0279421 |
| SMIM44 | small integral membrane protein 44 | -0.0279226 |
| ITGAV | integrin, alpha V | -0.0277268 |
| C11ORF54 | chromosome 11 open reading frame 54 | -0.0275687 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0274367 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0272175 |
| SNX6 | sorting nexin 6 | -0.0271565 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0271539 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0268813 |
| RB1 | retinoblastoma 1 | -0.0268812 |
| AK1 | adenylate kinase 1 | -0.0268016 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0267893 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0267778 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.026765 |
| RBMX | RNA binding motif protein, X-linked | -0.0267448 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0266901 |
| ZC3H6 | zinc finger CCCH-type containing 6 | -0.0266293 |
| NALCN | sodium leak channel, non selective | -0.0266262 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0264637 |
| FAM168B | family with sequence similarity 168, member B | -0.0264579 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0264357 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0263481 |
| ZFP91 | ZFP91 zinc finger protein | -0.0262837 |
| DGKH | diacylglycerol kinase, eta | -0.0261918 |
| CENPP | centromere protein P | -0.0261471 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0260596 |
| USP53 | ubiquitin specific peptidase 53 | -0.0258878 |
| LMO7 | LIM domain 7 | -0.0256003 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.025556 |
| RPL36 | ribosomal protein L36 | -0.0255029 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0250052 |
| SRPK1 | SRSF protein kinase 1 | -0.0249493 |
| TMEM167A | transmembrane protein 167A | -0.0246406 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0246363 |
| CASP8AP2 | caspase 8 associated protein 2 | -0.0245482 |
