| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Finasteride perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Finasteride_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.142829 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.13277 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.116609 |
| VEGFA | vascular endothelial growth factor A | 0.0972516 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0930705 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0789911 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0760932 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.062093 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.061424 |
| SMAD3 | SMAD family member 3 | 0.057269 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0571361 |
| SUCO | SUN domain containing ossification factor | 0.0530488 |
| RNF145 | ring finger protein 145 | 0.0505151 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0496043 |
| AHR | aryl hydrocarbon receptor | 0.0486786 |
| CENPF | centromere protein F, 350/400kDa | 0.047081 |
| FAT1 | FAT atypical cadherin 1 | 0.0466031 |
| HELZ | helicase with zinc finger | 0.046478 |
| COPA | coatomer protein complex, subunit alpha | 0.0464267 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.045523 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0454499 |
| TPR | translocated promoter region, nuclear basket protein | 0.0454314 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0443342 |
| WDR26 | WD repeat domain 26 | 0.0442953 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.044008 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0438901 |
| GOLGA4 | golgin A4 | 0.0432636 |
| OGA | O-GlcNAcase | 0.0411725 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.040887 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.039638 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0395961 |
| VMP1 | vacuole membrane protein 1 | 0.0393457 |
| SMOX | spermine oxidase | 0.0390596 |
| DST | dystonin | 0.0390573 |
| COG5 | component of oligomeric golgi complex 5 | 0.0387976 |
| ETNK1 | ethanolamine kinase 1 | 0.0376965 |
| TFG | TRK-fused gene | 0.0373865 |
| PTK2 | protein tyrosine kinase 2 | 0.037002 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.036672 |
| PRELID2 | PRELI domain containing 2 | 0.036657 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0359746 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0355863 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.03552 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0354558 |
| NUP58 | nucleoporin 58 | 0.0353097 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0350801 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0349077 |
| ANKRD11 | ankyrin repeat domain 11 | 0.034426 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0341436 |
| RUNX1 | runt-related transcription factor 1 | 0.0340762 |
| NEK7 | NIMA-related kinase 7 | 0.033575 |
| CAB39 | calcium binding protein 39 | 0.0334184 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0332933 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0330638 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0329315 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0325293 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0323726 |
| FLNA | filamin A, alpha | 0.0323025 |
| RBM39 | RNA binding motif protein 39 | 0.0322222 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0320107 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0319863 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0317053 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0312989 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0312045 |
| SLTM | SAFB-like, transcription modulator | 0.0311944 |
| SMYD3 | SET and MYND domain containing 3 | 0.0311148 |
| AFDN | afadin, adherens junction formation factor | 0.0307405 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0302622 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0293879 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0291963 |
| ARRDC3 | arrestin domain containing 3 | 0.0290246 |
| WDR43 | WD repeat domain 43 | 0.0288896 |
| TPM3 | tropomyosin 3 | 0.0288442 |
| FAM13A | family with sequence similarity 13, member A | 0.0287543 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0286233 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0285646 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0284859 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0283648 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0281084 |
| ADAR | adenosine deaminase, RNA-specific | 0.028011 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0280028 |
| SFPQ | splicing factor proline/glutamine-rich | 0.027842 |
| CTBP2 | C-terminal binding protein 2 | 0.0274184 |
| NPTN | neuroplastin | 0.027266 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0272639 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0270669 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0268641 |
| CUL3 | cullin 3 | 0.0268112 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0266872 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0266549 |
| LOXL2 | lysyl oxidase-like 2 | 0.026269 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0262296 |
| RANBP2 | RAN binding protein 2 | 0.0257525 |
| TOP1 | topoisomerase (DNA) I | 0.0257401 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0256144 |
| TMEM165 | transmembrane protein 165 | 0.0254661 |
| CDC73 | cell division cycle 73 | 0.0253971 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0251844 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0251814 |
| CD109 | CD109 molecule | 0.0251805 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.216841 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.186748 |
| NRG1 | neuregulin 1 | -0.149707 |
| FN1 | fibronectin 1 | -0.128197 |
| PTMA | prothymosin, alpha | -0.122922 |
| FTL | ferritin, light polypeptide | -0.0974189 |
| TMSB10 | thymosin beta 10 | -0.095097 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.071367 |
| MT2A | metallothionein 2A | -0.0660476 |
| HLA-B | major histocompatibility complex, class I, B | -0.061986 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0569655 |
| SQSTM1 | sequestosome 1 | -0.0539201 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0538564 |
| S100A6 | S100 calcium binding protein A6 | -0.0525597 |
| HMGA2 | high mobility group AT-hook 2 | -0.0525432 |
| VIM | vimentin | -0.0522159 |
| ASPH | aspartate beta-hydroxylase | -0.0486177 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0483286 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0471722 |
| S100A10 | S100 calcium binding protein A10 | -0.0441934 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0436733 |
| IER3 | immediate early response 3 | -0.0430149 |
| RPL35A | ribosomal protein L35a | -0.0408175 |
| LMNA | lamin A/C | -0.0380616 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0379067 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0372373 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0354594 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0354084 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0351957 |
| RPL34 | ribosomal protein L34 | -0.0351608 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0337313 |
| H1-0 | H1.0 linker histone | -0.0324368 |
| RPS8 | ribosomal protein S8 | -0.0317149 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0307012 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0303869 |
| RPS24 | ribosomal protein S24 | -0.0302618 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0294479 |
| RPL12 | ribosomal protein L12 | -0.0286494 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0280227 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0276182 |
| RPS21 | ribosomal protein S21 | -0.0275435 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.027328 |
| RPLP1 | ribosomal protein, large, P1 | -0.0272285 |
| RAI14 | retinoic acid induced 14 | -0.0269989 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0266521 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0264409 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0262505 |
| ACTG1 | actin gamma 1 | -0.0260131 |
| RPL31 | ribosomal protein L31 | -0.0258013 |
| RPS19 | ribosomal protein S19 | -0.0255299 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0253377 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.025192 |
| RPS6 | ribosomal protein S6 | -0.0250393 |
| NTN4 | netrin 4 | -0.0248814 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.024705 |
| ETV1 | ets variant 1 | -0.024107 |
| SYT1 | synaptotagmin I | -0.0240684 |
| CTSD | cathepsin D | -0.0240627 |
| HLA-A | major histocompatibility complex, class I, A | -0.0239103 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0238451 |
| GNAS | GNAS complex locus | -0.0234111 |
| RPS27A | ribosomal protein S27a | -0.022691 |
| RPL38 | ribosomal protein L38 | -0.0226059 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0225839 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0216626 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0216454 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0215682 |
| VCL | vinculin | -0.0209753 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0208125 |
| MT1X | metallothionein 1X | -0.0205275 |
| EGR1 | early growth response 1 | -0.0203696 |
| TENM4 | teneurin transmembrane protein 4 | -0.0202988 |
| HMGA1 | high mobility group AT-hook 1 | -0.0202527 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0201957 |
| RPS11 | ribosomal protein S11 | -0.0201664 |
| LOX | lysyl oxidase | -0.0201499 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0199446 |
| RPL19 | ribosomal protein L19 | -0.019384 |
| BPTF | bromodomain PHD finger transcription factor | -0.019246 |
| EFNA5 | ephrin-A5 | -0.0192154 |
| S100A9 | S100 calcium binding protein A9 | -0.019071 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0189906 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0186856 |
| RPLP2 | ribosomal protein, large, P2 | -0.0186424 |
| RPS27 | ribosomal protein S27 | -0.0183905 |
| INTS6 | integrator complex subunit 6 | -0.0181558 |
| RPL32 | ribosomal protein L32 | -0.0180655 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0180138 |
| HMGB1 | high mobility group box 1 | -0.0179389 |
| RPL37A | ribosomal protein L37a | -0.0174958 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | -0.0173778 |
| RPL36AL | ribosomal protein L36a-like | -0.0171728 |
| DUSP6 | dual specificity phosphatase 6 | -0.0170377 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0170064 |
| PALLD | palladin, cytoskeletal associated protein | -0.0169966 |
| TAGLN2 | transgelin 2 | -0.0169507 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.016881 |
| PLIN2 | perilipin 2 | -0.0168483 |
| AEBP2 | AE binding protein 2 | -0.0168245 |
| ASTN2 | astrotactin 2 | -0.0167482 |
