| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fingolimod (hydrochloride)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0536706 |
| RPS2 | ribosomal protein S2 | 0.0493835 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0469132 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0425727 |
| XPO1 | exportin 1 | 0.0376368 |
| PCBP2 | poly(rC) binding protein 2 | 0.0356388 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0319776 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0319536 |
| ZNF292 | zinc finger protein 292 | 0.0274449 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0274142 |
| CCNL1 | cyclin L1 | 0.0269762 |
| KIF5B | kinesin family member 5B | 0.0267907 |
| CPOX | coproporphyrinogen oxidase | 0.0262393 |
| MGAT4C | MGAT4 family, member C | 0.0246368 |
| CLTC | clathrin, heavy chain (Hc) | 0.0244249 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0241217 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0240588 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0239404 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0235393 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.023166 |
| THOC1 | THO complex 1 | 0.0229821 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0228009 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0227591 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0223058 |
| NEK7 | NIMA-related kinase 7 | 0.0222442 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0221483 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0220611 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0219023 |
| MATR3 | matrin 3 | 0.0218604 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0218176 |
| TXNRD1 | thioredoxin reductase 1 | 0.0218149 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0218014 |
| SETD5 | SET domain containing 5 | 0.0217726 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0215919 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0210927 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0209559 |
| KLHL24 | kelch-like family member 24 | 0.0207441 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0206383 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0199887 |
| MED13L | mediator complex subunit 13-like | 0.0197703 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0195937 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0194007 |
| IL6ST | interleukin 6 signal transducer | 0.0193143 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0192738 |
| PNN | pinin, desmosome associated protein | 0.019116 |
| EPHA6 | EPH receptor A6 | 0.0187986 |
| RPL3 | ribosomal protein L3 | 0.0186207 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0185256 |
| TPM3 | tropomyosin 3 | 0.0184826 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0184141 |
| TBK1 | TANK-binding kinase 1 | 0.0183815 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0183535 |
| RBM27 | RNA binding motif protein 27 | 0.0181377 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0181105 |
| PRKCI | protein kinase C, iota | 0.0180389 |
| NCKAP1 | NCK-associated protein 1 | 0.0180364 |
| U2SURP | U2 snRNP-associated SURP domain containing | 0.0179104 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0177355 |
| SPAG9 | sperm associated antigen 9 | 0.0176838 |
| PLK2 | polo-like kinase 2 | 0.0176369 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.0175147 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0175004 |
| TFG | TRK-fused gene | 0.0174384 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0174382 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0174282 |
| OGA | O-GlcNAcase | 0.0173516 |
| NUP58 | nucleoporin 58 | 0.0172929 |
| CEP192 | centrosomal protein 192kDa | 0.017181 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0169121 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0168113 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0166189 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0164824 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0164803 |
| PCM1 | pericentriolar material 1 | 0.0164415 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.016429 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.016395 |
| YEATS2 | YEATS domain containing 2 | 0.0163722 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0162678 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0161431 |
| DST | dystonin | 0.0160723 |
| ARRDC3 | arrestin domain containing 3 | 0.0160532 |
| YBX3 | Y box binding protein 3 | 0.0160348 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.015841 |
| USP34 | ubiquitin specific peptidase 34 | 0.0157816 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0157598 |
| TPR | translocated promoter region, nuclear basket protein | 0.0156732 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 0.0156445 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0154488 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0154124 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0153818 |
| SON | SON DNA binding protein | 0.0153745 |
| OXR1 | oxidation resistance 1 | 0.0153681 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0153482 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0151644 |
| ANXA1 | annexin A1 | 0.0151534 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0151524 |
| PAPOLA | poly(A) polymerase alpha | 0.0148135 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0145219 |
| YBX1 | Y box binding protein 1 | 0.0145217 |
| ETNK1 | ethanolamine kinase 1 | 0.014471 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.22705 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.128853 |
| NLGN1 | neuroligin 1 | -0.113223 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.110549 |
| TMSB10 | thymosin beta 10 | -0.101312 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.090759 |
| HMGA2 | high mobility group AT-hook 2 | -0.0812997 |
| PTMA | prothymosin, alpha | -0.0736495 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0672121 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0649358 |
| RPL35A | ribosomal protein L35a | -0.0644679 |
| ACTG1 | actin gamma 1 | -0.0643242 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0544016 |
| EHBP1 | EH domain binding protein 1 | -0.0490384 |
| EGR1 | early growth response 1 | -0.0467343 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0430518 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0427391 |
| PCDH7 | protocadherin 7 | -0.0423287 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0391566 |
| RPS27A | ribosomal protein S27a | -0.0384471 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0379048 |
| INTS6 | integrator complex subunit 6 | -0.0354534 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.035404 |
| NHSL1 | NHS-like 1 | -0.0353329 |
| RPS8 | ribosomal protein S8 | -0.0345108 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0327509 |
| RPLP1 | ribosomal protein, large, P1 | -0.03236 |
| ASPH | aspartate beta-hydroxylase | -0.0321361 |
| TUBA1B | tubulin, alpha 1b | -0.0315894 |
| RPL23 | ribosomal protein L23 | -0.0311377 |
| ZNF804A | zinc finger protein 804A | -0.0297226 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0281831 |
| RPL37A | ribosomal protein L37a | -0.0279961 |
| RPS13 | ribosomal protein S13 | -0.0279693 |
| RPS24 | ribosomal protein S24 | -0.027842 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0278348 |
| RASAL2 | RAS protein activator like 2 | -0.0276535 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0270695 |
| RPS23 | ribosomal protein S23 | -0.0268665 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0262534 |
| RPS29 | ribosomal protein S29 | -0.0258516 |
| S100A10 | S100 calcium binding protein A10 | -0.0252494 |
| RPLP2 | ribosomal protein, large, P2 | -0.0246716 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0241453 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.024116 |
| PRDX1 | peroxiredoxin 1 | -0.024099 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0238859 |
| CMIP | c-Maf inducing protein | -0.0238786 |
| RPL34 | ribosomal protein L34 | -0.0238023 |
| RPL31 | ribosomal protein L31 | -0.0236741 |
| RPL9 | ribosomal protein L9 | -0.0234228 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0230579 |
| AREG | amphiregulin | -0.0228806 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0228161 |
| CUX1 | cut-like homeobox 1 | -0.0227035 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0226793 |
| LRRC23 | leucine rich repeat containing 23 | -0.0224165 |
| YAP1 | Yes-associated protein 1 | -0.0223905 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0221838 |
| ADIPOR2 | adiponectin receptor 2 | -0.0221572 |
| MTAP | methylthioadenosine phosphorylase | -0.022153 |
| AHNAK | AHNAK nucleoprotein | -0.021779 |
| RPS3 | ribosomal protein S3 | -0.0217726 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0210632 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0208316 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.020591 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0205487 |
| RPL37 | ribosomal protein L37 | -0.0205119 |
| CCND1 | cyclin D1 | -0.0202648 |
| CAVIN1 | caveolae associated protein 1 | -0.0199866 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0197696 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.019588 |
| CALR | calreticulin | -0.0195509 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0194236 |
| FTL | ferritin, light polypeptide | -0.0193952 |
| RPS6 | ribosomal protein S6 | -0.01939 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.019261 |
| TPI1 | triosephosphate isomerase 1 | -0.0190259 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0189901 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0187871 |
| TBCA | tubulin folding cofactor A | -0.0186488 |
| BRI3BP | BRI3 binding protein | -0.0186426 |
| BPTF | bromodomain PHD finger transcription factor | -0.0184752 |
| ENO1 | enolase 1, (alpha) | -0.0183664 |
| RPS11 | ribosomal protein S11 | -0.0183219 |
| R3HDM2 | R3H domain containing 2 | -0.0182836 |
| RPL38 | ribosomal protein L38 | -0.0182017 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0178219 |
| TUBA1C | tubulin, alpha 1c | -0.0176118 |
| GCG | glucagon | -0.0175081 |
| NABP1 | nucleic acid binding protein 1 | -0.0174029 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0173406 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0172644 |
| EDARADD | EDAR-associated death domain | -0.0172185 |
| DOCK1 | dedicator of cytokinesis 1 | -0.017202 |
| HMGB1 | high mobility group box 1 | -0.0170497 |
| RPS14 | ribosomal protein S14 | -0.0170118 |
| TPM4 | tropomyosin 4 | -0.0165028 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0164891 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0164738 |
