| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fingolimod (hydrochloride)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.21413 |
| MEST | mesoderm specific transcript | 0.188623 |
| VIM | vimentin | 0.102445 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0931146 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0832733 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0826143 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0802026 |
| CADM2 | cell adhesion molecule 2 | 0.0797067 |
| MGP | matrix Gla protein | 0.0776252 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0687989 |
| HMGA2 | high mobility group AT-hook 2 | 0.0660857 |
| PCM1 | pericentriolar material 1 | 0.0619929 |
| ATXN2 | ataxin 2 | 0.0552681 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.054875 |
| PEG10 | paternally expressed 10 | 0.0543415 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0530465 |
| JMJD1C | jumonji domain containing 1C | 0.0528882 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0524108 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0514704 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0496826 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0492923 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0489447 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.047432 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0473308 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0470933 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0455004 |
| CTBP2 | C-terminal binding protein 2 | 0.0452186 |
| EGFR | epidermal growth factor receptor | 0.0446391 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0442399 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0437028 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.043033 |
| GOLGA4 | golgin A4 | 0.0424575 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0424221 |
| KAZN | kazrin, periplakin interacting protein | 0.0422348 |
| PLS3 | plastin 3 | 0.0421619 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0407423 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0407064 |
| VEGFA | vascular endothelial growth factor A | 0.0406888 |
| ERBIN | erbb2 interacting protein | 0.0405905 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0404392 |
| ZFHX3 | zinc finger homeobox 3 | 0.040238 |
| TPK1 | thiamin pyrophosphokinase 1 | 0.0400021 |
| HDAC2 | histone deacetylase 2 | 0.0398032 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0395331 |
| ACTG1 | actin gamma 1 | 0.0391885 |
| FRMD6 | FERM domain containing 6 | 0.0390723 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | 0.0389393 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0386853 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0383385 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0382665 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.037944 |
| PHF3 | PHD finger protein 3 | 0.0376667 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.037334 |
| PTK2 | protein tyrosine kinase 2 | 0.0369337 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0364318 |
| YBX1 | Y box binding protein 1 | 0.0363263 |
| MEOX2 | mesenchyme homeobox 2 | 0.0356213 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0352682 |
| TRERF1 | transcriptional regulating factor 1 | 0.0352028 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0351797 |
| RAD51B | RAD51 paralog B | 0.0351077 |
| NBEA | neurobeachin | 0.0350892 |
| FAM13A | family with sequence similarity 13, member A | 0.0345997 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0342667 |
| PRELID2 | PRELI domain containing 2 | 0.0341698 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0340788 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0337654 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0336531 |
| LDHA | lactate dehydrogenase A | 0.0324709 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0321548 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0317806 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.031214 |
| RREB1 | ras responsive element binding protein 1 | 0.0310529 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | 0.0309858 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0300945 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0298878 |
| TOP1 | topoisomerase (DNA) I | 0.0294416 |
| HMGA1 | high mobility group AT-hook 1 | 0.0291082 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0290805 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0290311 |
| MICU1 | mitochondrial calcium uptake 1 | 0.0289182 |
| TBCA | tubulin folding cofactor A | 0.0287184 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0285995 |
| FTL | ferritin, light polypeptide | 0.0283755 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.0280927 |
| RPS6 | ribosomal protein S6 | 0.0280606 |
| PDE8A | phosphodiesterase 8A | 0.0279884 |
| TPI1 | triosephosphate isomerase 1 | 0.0279513 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0275781 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0274877 |
| COL1A2 | collagen, type I, alpha 2 | 0.0272561 |
| SCRN1 | secernin 1 | 0.027216 |
| SCFD1 | sec1 family domain containing 1 | 0.0271648 |
| SIK3 | SIK family kinase 3 | 0.0267375 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0267208 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0266057 |
| FLNB | filamin B, beta | 0.0264643 |
| TNRC6C | trinucleotide repeat containing 6C | 0.0264392 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0262423 |
| NUDCD3 | NudC domain containing 3 | 0.0260932 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGB2 | high mobility group box 2 | -0.0557961 |
| MT2A | metallothionein 2A | -0.0478319 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.046714 |
| RPS23 | ribosomal protein S23 | -0.0403262 |
| MYEF2 | myelin expression factor 2 | -0.0356477 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0344131 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0321381 |
| ZNF207 | zinc finger protein 207 | -0.0315198 |
| SEPTIN7 | septin 7 | -0.0303781 |
| MALSU1 | mitochondrial assembly of ribosomal large subunit 1 | -0.0295103 |
| H1-4 | H1.4 linker histone, cluster member | -0.0294277 |
| EXOC6B | exocyst complex component 6B | -0.0284337 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0275239 |
| KIF11 | kinesin family member 11 | -0.0271815 |
| CENPF | centromere protein F, 350/400kDa | -0.0263369 |
| WDR26 | WD repeat domain 26 | -0.0262073 |
| CENPE | centromere protein E, 312kDa | -0.0249342 |
| EPS15 | epidermal growth factor receptor pathway substrate 15 | -0.0247194 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0238127 |
| SON | SON DNA binding protein | -0.0236674 |
| IREB2 | iron-responsive element binding protein 2 | -0.0236482 |
| RDX | radixin | -0.0231628 |
| ANLN | anillin, actin binding protein | -0.023135 |
| CEP55 | centrosomal protein 55kDa | -0.0230032 |
| RPL38 | ribosomal protein L38 | -0.0229591 |
| ANO10 | anoctamin 10 | -0.0228913 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0227744 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | -0.0226589 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | -0.0224213 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0224127 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0223758 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase | -0.0223534 |
| CMC2 | C-x(9)-C motif containing 2 | -0.0218401 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.021542 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0214612 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0212985 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0211453 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0210651 |
| SMAP1 | small ArfGAP 1 | -0.0208797 |
| DCP2 | decapping mRNA 2 | -0.020866 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0206569 |
| YTHDC2 | YTH domain containing 2 | -0.020645 |
| ZC3H6 | zinc finger CCCH-type containing 6 | -0.0205904 |
| SFSWAP | splicing factor, suppressor of white-apricot family | -0.0204682 |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 | -0.0204325 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | -0.0203022 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0202186 |
| YME1L1 | YME1-like 1 ATPase | -0.0201959 |
| SBF2 | SET binding factor 2 | -0.0201228 |
| RPS29 | ribosomal protein S29 | -0.0199801 |
| RPL36 | ribosomal protein L36 | -0.0198312 |
| OGA | O-GlcNAcase | -0.0197988 |
| ATP9B | ATPase, class II, type 9B | -0.0197916 |
| IER3 | immediate early response 3 | -0.0196804 |
| RPLP2 | ribosomal protein, large, P2 | -0.0195449 |
| WTAP | Wilms tumor 1 associated protein | -0.0193128 |
| RHEB | Ras homolog enriched in brain | -0.019263 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0191522 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | -0.0191204 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0190869 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0189946 |
| GLG1 | golgi glycoprotein 1 | -0.0188943 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.018856 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0187114 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0186445 |
| ZNF107 | zinc finger protein 107 | -0.018631 |
| CKAP2L | cytoskeleton associated protein 2-like | -0.0185086 |
| FAM135A | family with sequence similarity 135, member A | -0.0184909 |
| SMC1A | structural maintenance of chromosomes 1A | -0.0184463 |
| KIAA1958 | KIAA1958 | -0.0184012 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0182376 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | -0.0182098 |
| RPL37 | ribosomal protein L37 | -0.0182014 |
| SQSTM1 | sequestosome 1 | -0.0181457 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | -0.0180217 |
| TMEM131 | transmembrane protein 131 | -0.0180183 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0179827 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.0179129 |
| ZNF608 | zinc finger protein 608 | -0.0178444 |
| ZNF652 | zinc finger protein 652 | -0.0176231 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0175308 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0175149 |
| WDR44 | WD repeat domain 44 | -0.0174788 |
| NCAPG | non-SMC condensin I complex, subunit G | -0.0174776 |
| USP3 | ubiquitin specific peptidase 3 | -0.0174179 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0173857 |
| GMPS | guanine monphosphate synthase | -0.0173603 |
| RPS27A | ribosomal protein S27a | -0.0173284 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0172922 |
| KIF20B | kinesin family member 20B | -0.0172637 |
| CEP192 | centrosomal protein 192kDa | -0.017246 |
| TUBB | tubulin, beta class I | -0.0170576 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0170193 |
| RPL6 | ribosomal protein L6 | -0.0170127 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0170061 |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 | -0.0169848 |
| ZFP91 | ZFP91 zinc finger protein | -0.0169832 |
| THUMPD2 | THUMP domain containing 2 | -0.0169075 |
| MKI67 | marker of proliferation Ki-67 | -0.016745 |
| TIPRL | TOR signaling pathway regulator | -0.0167358 |
