| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fingolimod (hydrochloride)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.0855089 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0551983 |
| KLK10 | kallikrein-related peptidase 10 | 0.0535576 |
| FTL | ferritin, light polypeptide | 0.0529739 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0511198 |
| MXD1 | MAX dimerization protein 1 | 0.0438159 |
| RPS2 | ribosomal protein S2 | 0.0396276 |
| LAMB3 | laminin, beta 3 | 0.0375554 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0318291 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0314166 |
| RPS6 | ribosomal protein S6 | 0.0290625 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0267207 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0255773 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0252115 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0240041 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0236892 |
| CLMP | CXADR-like membrane protein | 0.0232051 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0228878 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0224118 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0221671 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0215259 |
| RPL35A | ribosomal protein L35a | 0.0184703 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0183872 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0176285 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0173597 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0166594 |
| HMGA1 | high mobility group AT-hook 1 | 0.0156332 |
| COPA | coatomer protein complex, subunit alpha | 0.015469 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0153063 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0151954 |
| RAB1A | RAB1A, member RAS oncogene family | 0.014915 |
| UPP1 | uridine phosphorylase 1 | 0.014793 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | 0.0145494 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0141639 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.013798 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0137601 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0137104 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0136226 |
| EGR1 | early growth response 1 | 0.0135419 |
| RPL38 | ribosomal protein L38 | 0.0135326 |
| ZC3H3 | zinc finger CCCH-type containing 3 | 0.013474 |
| MCU | mitochondrial calcium uniporter | 0.0134502 |
| ABHD3 | abhydrolase domain containing 3 | 0.0133751 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0131841 |
| RCOR1 | REST corepressor 1 | 0.0129674 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0125944 |
| INTS6 | integrator complex subunit 6 | 0.0125745 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0125431 |
| SMNDC1 | survival motor neuron domain containing 1 | 0.0124219 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0123777 |
| SEC24A | SEC24 family member A | 0.0122399 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0122152 |
| ZNF706 | zinc finger protein 706 | 0.0122084 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0121165 |
| FOSL1 | FOS-like antigen 1 | 0.0120394 |
| RBM39 | RNA binding motif protein 39 | 0.0119306 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0119241 |
| DENND2C | DENN/MADD domain containing 2C | 0.0118401 |
| MTDH | metadherin | 0.0117765 |
| CCNL1 | cyclin L1 | 0.0117231 |
| MORF4L2 | mortality factor 4 like 2 | 0.0116015 |
| NOP58 | NOP58 ribonucleoprotein | 0.0115797 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0115718 |
| SLK | STE20-like kinase | 0.0115602 |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.0115011 |
| HM13 | histocompatibility (minor) 13 | 0.011439 |
| RPL37A | ribosomal protein L37a | 0.0113762 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0112811 |
| AK1 | adenylate kinase 1 | 0.0112604 |
| PRR13 | proline rich 13 | 0.0111287 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0111234 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0109793 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0109386 |
| PRKCI | protein kinase C, iota | 0.0107745 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0106674 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0106245 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0105951 |
| SPAG9 | sperm associated antigen 9 | 0.01057 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0104926 |
| SDC1 | syndecan 1 | 0.0104605 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0104603 |
| GOLGB1 | golgin B1 | 0.010452 |
| ACTG1 | actin gamma 1 | 0.0103339 |
| TGFA | transforming growth factor, alpha | 0.0103246 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0102283 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.010179 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0101574 |
| CLINT1 | clathrin interactor 1 | 0.010084 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.010046 |
| UBQLN1 | ubiquilin 1 | 0.0100299 |
| PTMA | prothymosin, alpha | 0.00999065 |
| ZNF83 | zinc finger protein 83 | 0.00998147 |
| PGM3 | phosphoglucomutase 3 | 0.00995274 |
| RPL31 | ribosomal protein L31 | 0.00993154 |
| WAC | WW domain containing adaptor with coiled-coil | 0.00982214 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.00970373 |
| UBAP2 | ubiquitin associated protein 2 | 0.00969937 |
| NXN | nucleoredoxin | 0.00965129 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.00961867 |
| SLMAP | sarcolemma associated protein | 0.00954509 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.216183 |
| AHNAK | AHNAK nucleoprotein | -0.134429 |
| FLNB | filamin B, beta | -0.115018 |
| TMSB10 | thymosin beta 10 | -0.109357 |
| VIM | vimentin | -0.108268 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0857902 |
| ITGA6 | integrin, alpha 6 | -0.068654 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0631741 |
| SMAD3 | SMAD family member 3 | -0.0589584 |
| EGFR | epidermal growth factor receptor | -0.0578606 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0563502 |
| ASPH | aspartate beta-hydroxylase | -0.0562872 |
| S100A10 | S100 calcium binding protein A10 | -0.055505 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0539335 |
| SDC4 | syndecan 4 | -0.0534661 |
| LDHA | lactate dehydrogenase A | -0.0532855 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0528115 |
| EFNA5 | ephrin-A5 | -0.0512517 |
| RPS27A | ribosomal protein S27a | -0.047109 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0455618 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0445022 |
| EMP1 | epithelial membrane protein 1 | -0.0427384 |
| EZR | ezrin | -0.0418045 |
| SLC38A2 | solute carrier family 38, member 2 | -0.04116 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.040534 |
| NDRG1 | N-myc downstream regulated 1 | -0.0404645 |
| MYOF | myoferlin | -0.0392324 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0382412 |
| KRT8 | keratin 8, type II | -0.0354563 |
| ENO1 | enolase 1, (alpha) | -0.03465 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0339425 |
| PCBP2 | poly(rC) binding protein 2 | -0.0338055 |
| KLF6 | Kruppel-like factor 6 | -0.0317619 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0310328 |
| ITGB4 | integrin, beta 4 | -0.0304716 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0303998 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0303646 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0294798 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0293922 |
| FOXO1 | forkhead box O1 | -0.0291772 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0290633 |
| RTN4 | reticulon 4 | -0.0288999 |
| ARHGAP42 | Rho GTPase activating protein 42 | -0.0283469 |
| ANXA2 | annexin A2 | -0.0279506 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0277795 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0273734 |
| OGA | O-GlcNAcase | -0.0268957 |
| ACTN4 | actinin, alpha 4 | -0.026264 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0258125 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.025718 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0255478 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.025085 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0247699 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0234845 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0231587 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0229419 |
| S100A6 | S100 calcium binding protein A6 | -0.0228035 |
| CORO1C | coronin, actin binding protein, 1C | -0.0228019 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0227468 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0224633 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0223865 |
| VCL | vinculin | -0.0220309 |
| FAT1 | FAT atypical cadherin 1 | -0.0218883 |
| PLEC | plectin | -0.0218342 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.0216323 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0213317 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0211928 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0211385 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0207807 |
| NEK7 | NIMA-related kinase 7 | -0.0206807 |
| MED13L | mediator complex subunit 13-like | -0.0204002 |
| RPL23 | ribosomal protein L23 | -0.0203537 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0203138 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0202534 |
| JUN | jun proto-oncogene | -0.0200838 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0198192 |
| VCAN | versican | -0.0197851 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0197568 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0197085 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0195973 |
| CAB39 | calcium binding protein 39 | -0.0193661 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0192457 |
| PKM | pyruvate kinase, muscle | -0.019213 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0191641 |
| PERP | PERP, TP53 apoptosis effector | -0.0189442 |
| DUSP6 | dual specificity phosphatase 6 | -0.018673 |
| ANO6 | anoctamin 6 | -0.018646 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0185338 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0184459 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0183901 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0183737 |
| STK39 | serine threonine kinase 39 | -0.0180645 |
| TGM2 | transglutaminase 2 | -0.0179558 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0179309 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0175486 |
| APAF1 | apoptotic peptidase activating factor 1 | -0.0173234 |
| FHL2 | four and a half LIM domains 2 | -0.0173073 |
| PRELID2 | PRELI domain containing 2 | -0.0172943 |
| WWC1 | WW and C2 domain containing 1 | -0.0169912 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0169216 |
