| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fingolimod (hydrochloride)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.185788 |
| CLTC | clathrin, heavy chain (Hc) | 0.123288 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.109629 |
| NCOA3 | nuclear receptor coactivator 3 | 0.097123 |
| NDRG1 | N-myc downstream regulated 1 | 0.0945323 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0746041 |
| DSPP | dentin sialophosphoprotein | 0.059067 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0561897 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0554014 |
| ASPH | aspartate beta-hydroxylase | 0.0553877 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0502976 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0496329 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0495761 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.048242 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0476806 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.047051 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.0469621 |
| SET | SET nuclear proto-oncogene | 0.0438736 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0431598 |
| VEGFA | vascular endothelial growth factor A | 0.0429142 |
| CEP250 | centrosomal protein 250kDa | 0.0420644 |
| LDHA | lactate dehydrogenase A | 0.041683 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0416123 |
| ENO1 | enolase 1, (alpha) | 0.0394524 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.039025 |
| ACTG1 | actin gamma 1 | 0.0381772 |
| EGFR | epidermal growth factor receptor | 0.0379227 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0376286 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.035928 |
| BBX | bobby sox homolog (Drosophila) | 0.0354366 |
| LASP1 | LIM and SH3 protein 1 | 0.0350845 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0348681 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.034695 |
| SBF2 | SET binding factor 2 | 0.0337535 |
| GOLGB1 | golgin B1 | 0.0335994 |
| ANKRD12 | ankyrin repeat domain 12 | 0.033568 |
| CANX | calnexin | 0.0332763 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0328869 |
| TPM3 | tropomyosin 3 | 0.0326886 |
| TMEM123 | transmembrane protein 123 | 0.0325424 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0320443 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0318781 |
| TPD52 | tumor protein D52 | 0.0317523 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0316101 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0311545 |
| PTMA | prothymosin, alpha | 0.0303283 |
| FOXO3 | forkhead box O3 | 0.0302587 |
| PKM | pyruvate kinase, muscle | 0.0300096 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0299335 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0298605 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.029579 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0294167 |
| PGK1 | phosphoglycerate kinase 1 | 0.029383 |
| VMP1 | vacuole membrane protein 1 | 0.0293322 |
| PRELID2 | PRELI domain containing 2 | 0.0293103 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.028947 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0288303 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0287073 |
| YEATS2 | YEATS domain containing 2 | 0.0286016 |
| EZR | ezrin | 0.028546 |
| ZNF292 | zinc finger protein 292 | 0.0282125 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0279887 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0279161 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0278224 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0278112 |
| USO1 | USO1 vesicle transport factor | 0.0277865 |
| APP | amyloid beta (A4) precursor protein | 0.0277515 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.027609 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0275468 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0273137 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0271656 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0270659 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0270617 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0269907 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.026946 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0268981 |
| POTEF | POTE ankyrin domain family, member F | 0.0267169 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.026263 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0262327 |
| TMEM165 | transmembrane protein 165 | 0.0259509 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0247778 |
| CCNY | cyclin Y | 0.0245418 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.024111 |
| MMP24OS | MMP24 opposite strand | 0.0240289 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0236182 |
| YAP1 | Yes-associated protein 1 | 0.0235922 |
| UBC | ubiquitin C | 0.0232409 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | 0.0232216 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0230555 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0229823 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0226879 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0226548 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0226465 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0221541 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.022137 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0220146 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0218629 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0215561 |
| FAM13A | family with sequence similarity 13, member A | 0.0215404 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0215109 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CATSPERB | catsper channel auxiliary subunit beta | -0.0591272 |
| NTN4 | netrin 4 | -0.0293425 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0265607 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0249181 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0229394 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0228371 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0227893 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.019663 |
| ENAH | enabled homolog (Drosophila) | -0.0181241 |
| RPL23 | ribosomal protein L23 | -0.0179441 |
| FASN | fatty acid synthase | -0.0164206 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0153473 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | -0.015191 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0149861 |
| SP100 | SP100 nuclear antigen | -0.0146413 |
| GRHL1 | grainyhead-like 1 (Drosophila) | -0.0143511 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.014005 |
| S100A8 | S100 calcium binding protein A8 | -0.0137262 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0136028 |
| TCEA2 | transcription elongation factor A (SII), 2 | -0.0135045 |
| CDK12 | cyclin-dependent kinase 12 | -0.0131024 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0129312 |
| PMP22 | peripheral myelin protein 22 | -0.0127596 |
| GLCCI1 | glucocorticoid induced 1 | -0.0123879 |
| HMGB1 | high mobility group box 1 | -0.0123 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -0.012287 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0121937 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0119061 |
| KLF6 | Kruppel-like factor 6 | -0.0114904 |
| KAZN | kazrin, periplakin interacting protein | -0.0112578 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0111644 |
| OLA1 | Obg-like ATPase 1 | -0.0111446 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0109161 |
| MAP7 | microtubule-associated protein 7 | -0.0108024 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0107501 |
| RPL9 | ribosomal protein L9 | -0.0106767 |
| RPS12 | ribosomal protein S12 | -0.010647 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0106454 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0106035 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0105415 |
| NRP1 | neuropilin 1 | -0.0105121 |
| WDR43 | WD repeat domain 43 | -0.0104854 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0104629 |
| RAB1B | RAB1B, member RAS oncogene family | -0.0102826 |
| RPS8 | ribosomal protein S8 | -0.0100706 |
| WWOX | WW domain containing oxidoreductase | -0.0100684 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | -0.00999658 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00997424 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00974352 |
| NAPG | N-ethylmaleimide-sensitive factor attachment protein, gamma | -0.00972163 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.00968276 |
| CADM2 | cell adhesion molecule 2 | -0.00959757 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.0095053 |
| RPL35A | ribosomal protein L35a | -0.00941416 |
| NCOA7 | nuclear receptor coactivator 7 | -0.00937053 |
| EFNA5 | ephrin-A5 | -0.00935834 |
| NREP | neuronal regeneration related protein | -0.00927227 |
| S100P | S100 calcium binding protein P | -0.00903592 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.00892844 |
| CUX1 | cut-like homeobox 1 | -0.00867823 |
| ZNF407 | zinc finger protein 407 | -0.00864671 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.00854992 |
| PLSCR1 | phospholipid scramblase 1 | -0.00853602 |
| PRXL2A | peroxiredoxin like 2A | -0.00844575 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.00842751 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.00840752 |
| TRIM5 | tripartite motif containing 5 | -0.00839887 |
| TP53INP2 | tumor protein p53 inducible nuclear protein 2 | -0.00832381 |
| SIK3 | SIK family kinase 3 | -0.00831174 |
| BICDL1 | BICD family like cargo adaptor 1 | -0.00823395 |
| CCDC59 | coiled-coil domain containing 59 | -0.00822593 |
| MYL12B | myosin, light chain 12B, regulatory | -0.00822114 |
| TBL1X | transducin (beta)-like 1X-linked | -0.00819083 |
| XRN2 | 5'-3' exoribonuclease 2 | -0.00815353 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.00813141 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.00803963 |
| RHOB | ras homolog family member B | -0.00801292 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0080103 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.00796974 |
| TTC6 | tetratricopeptide repeat domain 6 | -0.00795892 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.00794381 |
| STAC2 | SH3 and cysteine rich domain 2 | -0.00787635 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.00784628 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0078046 |
| SPATA13 | spermatogenesis associated 13 | -0.00777898 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.00775504 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | -0.00775453 |
| CREBBP | CREB binding protein | -0.00773658 |
| FDPS | farnesyl diphosphate synthase | -0.00768282 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.00767296 |
| PHF14 | PHD finger protein 14 | -0.00766031 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.00761887 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.00759128 |
| RBPMS | RNA binding protein with multiple splicing | -0.00743532 |
| SHLD1 | shieldin complex subunit 1 | -0.00743226 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.00742287 |
| RUNX2 | runt-related transcription factor 2 | -0.00742168 |
| ITGB5 | integrin, beta 5 | -0.00728362 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00715525 |
| PSMC1 | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | -0.00710317 |
