| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fingolimod (hydrochloride)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NEBL | nebulette | 0.112095 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0875225 |
| RPS2 | ribosomal protein S2 | 0.0866518 |
| RPS6 | ribosomal protein S6 | 0.057174 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0550562 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0538426 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0484127 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0470958 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0419277 |
| RCC1 | regulator of chromosome condensation 1 | 0.0417319 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.041729 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0415535 |
| CDH18 | cadherin 18, type 2 | 0.0380271 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0356623 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0347973 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0341716 |
| FMNL2 | formin-like 2 | 0.0337987 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0332696 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0317495 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0317479 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0311754 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0303839 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0298185 |
| ATP9A | ATPase, class II, type 9A | 0.0296809 |
| SET | SET nuclear proto-oncogene | 0.0286658 |
| HMGA1 | high mobility group AT-hook 1 | 0.0280788 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0279775 |
| RPS18 | ribosomal protein S18 | 0.0278814 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0275724 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0274941 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0274764 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0268936 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0268693 |
| PRICKLE1 | prickle homolog 1 (Drosophila) | 0.0265929 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0255862 |
| PDE7A | phosphodiesterase 7A | 0.0253048 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0252654 |
| RPL7 | ribosomal protein L7 | 0.0251919 |
| RPL3 | ribosomal protein L3 | 0.0248093 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0242403 |
| ZNF638 | zinc finger protein 638 | 0.0242265 |
| UBAP2 | ubiquitin associated protein 2 | 0.0240458 |
| PCNX4 | pecanex 4 | 0.0239953 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.023971 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0237977 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0234422 |
| WLS | wntless Wnt ligand secretion mediator | 0.0231471 |
| DENND1A | DENN/MADD domain containing 1A | 0.0231404 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) | 0.023028 |
| PAPOLA | poly(A) polymerase alpha | 0.0229613 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0229285 |
| ZNF146 | zinc finger protein 146 | 0.0228445 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0228057 |
| SNX14 | sorting nexin 14 | 0.0225943 |
| TBC1D32 | TBC1 domain family, member 32 | 0.0223119 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0223089 |
| CENPF | centromere protein F, 350/400kDa | 0.0221612 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0219409 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0219399 |
| SCFD1 | sec1 family domain containing 1 | 0.0217214 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0215908 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0214322 |
| CBX5 | chromobox homolog 5 | 0.0213498 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.0210361 |
| CCDC138 | coiled-coil domain containing 138 | 0.0209424 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0209196 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0208814 |
| RNF220 | ring finger protein 220 | 0.0208267 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0207533 |
| HDGF | hepatoma-derived growth factor | 0.0207512 |
| SBF2 | SET binding factor 2 | 0.0204347 |
| ZNF644 | zinc finger protein 644 | 0.0203832 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0203257 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0201419 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0200649 |
| USP37 | ubiquitin specific peptidase 37 | 0.0199954 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0196132 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0195459 |
| USP34 | ubiquitin specific peptidase 34 | 0.0194927 |
| VEGFA | vascular endothelial growth factor A | 0.0193874 |
| MSH4 | mutS homolog 4 | 0.0191901 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | 0.0191753 |
| PYGL | phosphorylase, glycogen, liver | 0.019175 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.019117 |
| RPS3 | ribosomal protein S3 | 0.0189377 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0188134 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0186168 |
| ATXN2 | ataxin 2 | 0.0185598 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0184522 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0182286 |
| SETD5 | SET domain containing 5 | 0.0181801 |
| NELFCD | negative elongation factor complex member C/D | 0.0181286 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0181088 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0180827 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0180496 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0180347 |
| SRPK1 | SRSF protein kinase 1 | 0.0178276 |
| UBE3A | ubiquitin protein ligase E3A | 0.0176565 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0176291 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.017621 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.107707 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0952584 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0812011 |
| UBC | ubiquitin C | -0.0799183 |
| CADM2 | cell adhesion molecule 2 | -0.0764876 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0734462 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0703653 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0699307 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0680573 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0678765 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0642879 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0617286 |
| EGR1 | early growth response 1 | -0.0616835 |
| RPL23 | ribosomal protein L23 | -0.0541019 |
| RTN4 | reticulon 4 | -0.0534573 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0534373 |
| RIGI | RNA sensor RIG-I | -0.0528706 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0520772 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0518805 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0515855 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0509829 |
| FBXO11 | F-box protein 11 | -0.0494104 |
| GNAS | GNAS complex locus | -0.0486423 |
| RPS27A | ribosomal protein S27a | -0.0479317 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0470984 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0463143 |
| HMGB1 | high mobility group box 1 | -0.04593 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0455454 |
| TMEM41B | transmembrane protein 41B | -0.0449443 |
| NFIA | nuclear factor I/A | -0.0429066 |
| ZNF608 | zinc finger protein 608 | -0.0422261 |
| OGA | O-GlcNAcase | -0.0421385 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0418201 |
| JMJD1C | jumonji domain containing 1C | -0.0413298 |
| TXNRD1 | thioredoxin reductase 1 | -0.0407353 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0404264 |
| PGK1 | phosphoglycerate kinase 1 | -0.0398933 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | -0.0398799 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0395219 |
| TMSB10 | thymosin beta 10 | -0.0392881 |
| RPLP1 | ribosomal protein, large, P1 | -0.0387155 |
| RPS4X | ribosomal protein S4, X-linked | -0.0385761 |
| TUBB | tubulin, beta class I | -0.0376825 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0375284 |
| VMP1 | vacuole membrane protein 1 | -0.0372795 |
| COL5A2 | collagen, type V, alpha 2 | -0.0369781 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0367768 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0365964 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.036536 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0364652 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0342869 |
| SEPTIN7 | septin 7 | -0.0342613 |
| FOXO3 | forkhead box O3 | -0.0342581 |
| HHIP | hedgehog interacting protein | -0.0340833 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | -0.0340589 |
| RPS24 | ribosomal protein S24 | -0.0338324 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.033727 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0333825 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0333278 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0331311 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0331287 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0330552 |
| ANXA2 | annexin A2 | -0.0330089 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0329998 |
| EXOC6B | exocyst complex component 6B | -0.0327544 |
| B2M | beta-2-microglobulin | -0.0321537 |
| JUN | jun proto-oncogene | -0.0321489 |
| LOC112694756 | uncharaterized LOC112694756 | -0.03213 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0313281 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0309572 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0307245 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.0302723 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0301573 |
| MAP1B | microtubule-associated protein 1B | -0.0300831 |
| PEG10 | paternally expressed 10 | -0.0298229 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0290859 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0289624 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0287965 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0282889 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0282371 |
| CAVIN1 | caveolae associated protein 1 | -0.0279547 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0279535 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0276865 |
| YBX1 | Y box binding protein 1 | -0.0273928 |
| IL6ST | interleukin 6 signal transducer | -0.0272252 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.0271976 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0271563 |
| SETX | senataxin | -0.0271136 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0269789 |
| PARD3 | par-3 family cell polarity regulator | -0.026709 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0266236 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0265999 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0264723 |
| IFRD1 | interferon-related developmental regulator 1 | -0.026239 |
| YAP1 | Yes-associated protein 1 | -0.0259988 |
| RBM39 | RNA binding motif protein 39 | -0.0258053 |
| UCK2 | uridine-cytidine kinase 2 | -0.0257241 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0257106 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0256359 |
| SHROOM3 | shroom family member 3 | -0.0256343 |
