| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fingolimod (hydrochloride)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.174529 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.103208 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0960468 |
| NDRG1 | N-myc downstream regulated 1 | 0.0850973 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.084831 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0746491 |
| PHF21A | PHD finger protein 21A | 0.0690354 |
| CDC73 | cell division cycle 73 | 0.0687739 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0666711 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0584151 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0572068 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0562009 |
| CD109 | CD109 molecule | 0.0552301 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0541684 |
| COPA | coatomer protein complex, subunit alpha | 0.0524352 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0522424 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0505411 |
| APP | amyloid beta (A4) precursor protein | 0.0496164 |
| NUP58 | nucleoporin 58 | 0.0488185 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0469736 |
| HELZ | helicase with zinc finger | 0.0464224 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0455877 |
| SRPK2 | SRSF protein kinase 2 | 0.0448425 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0444935 |
| RNF145 | ring finger protein 145 | 0.0435356 |
| ZNF292 | zinc finger protein 292 | 0.0431258 |
| PRELID2 | PRELI domain containing 2 | 0.041681 |
| SPAG9 | sperm associated antigen 9 | 0.0416692 |
| TMEM178B | transmembrane protein 178B | 0.0416383 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.041453 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0412513 |
| NBAS | neuroblastoma amplified sequence | 0.04114 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0411005 |
| CABIN1 | calcineurin binding protein 1 | 0.040755 |
| RBM33 | RNA binding motif protein 33 | 0.0405444 |
| VMP1 | vacuole membrane protein 1 | 0.0390573 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0387246 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0385454 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0376044 |
| SETD5 | SET domain containing 5 | 0.0375371 |
| AHR | aryl hydrocarbon receptor | 0.0368965 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0368854 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0361728 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0354469 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0353641 |
| A2M | alpha-2-macroglobulin | 0.0349766 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0344875 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.0342832 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0341572 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0340693 |
| TPD52 | tumor protein D52 | 0.0337175 |
| MRTFA | myocardin related transcription factor A | 0.032979 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0328788 |
| CCNL1 | cyclin L1 | 0.0328767 |
| CENPF | centromere protein F, 350/400kDa | 0.0323617 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0320605 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0316632 |
| POM121C | POM121 transmembrane nucleoporin C | 0.0311968 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0309771 |
| TPR | translocated promoter region, nuclear basket protein | 0.0308636 |
| INSIG2 | insulin induced gene 2 | 0.0306967 |
| FMNL2 | formin-like 2 | 0.0304779 |
| GOLGA4 | golgin A4 | 0.0303963 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.030272 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0301633 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0297197 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0296192 |
| FBXO7 | F-box protein 7 | 0.0294778 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0291572 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0287677 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0282533 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0280096 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0279711 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0277272 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0275681 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.0274756 |
| POTEF | POTE ankyrin domain family, member F | 0.0274753 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0272478 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.0270794 |
| TNPO3 | transportin 3 | 0.0270115 |
| PI15 | peptidase inhibitor 15 | 0.0269645 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.026685 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | 0.026473 |
| MCL1 | myeloid cell leukemia 1 | 0.0264403 |
| ANO6 | anoctamin 6 | 0.0263288 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.026227 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0259966 |
| XPO1 | exportin 1 | 0.0259647 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0256843 |
| ZNF654 | zinc finger protein 654 | 0.0255686 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0251795 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0250466 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0249491 |
| SEC24A | SEC24 family member A | 0.0248425 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0247329 |
| DOCK7 | dedicator of cytokinesis 7 | 0.024329 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0242823 |
| RLF | rearranged L-myc fusion | 0.0241199 |
| USP37 | ubiquitin specific peptidase 37 | 0.0238889 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0238758 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.11289 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.108493 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.08151 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0760706 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0675673 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0527302 |
| HLA-B | major histocompatibility complex, class I, B | -0.0523707 |
| FRMD4A | FERM domain containing 4A | -0.0456996 |
| TMSB10 | thymosin beta 10 | -0.0449513 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0429802 |
| ACTG1 | actin gamma 1 | -0.0404695 |
| RPS8 | ribosomal protein S8 | -0.0374721 |
| PTMA | prothymosin, alpha | -0.0373997 |
| RPLP1 | ribosomal protein, large, P1 | -0.037099 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.035904 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0323003 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.030489 |
| IER3 | immediate early response 3 | -0.0295335 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0286058 |
| AHNAK | AHNAK nucleoprotein | -0.0280573 |
| EHBP1 | EH domain binding protein 1 | -0.0274016 |
| HMGA2 | high mobility group AT-hook 2 | -0.0271502 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0266235 |
| PTCHD4 | patched domain containing 4 | -0.0250383 |
| RPL37A | ribosomal protein L37a | -0.0249502 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0239786 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0233634 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0233492 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0231261 |
| RPL9 | ribosomal protein L9 | -0.0229048 |
| RPL23 | ribosomal protein L23 | -0.0222195 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0220362 |
| FRMD5 | FERM domain containing 5 | -0.0219998 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0215788 |
| RRBP1 | ribosome binding protein 1 | -0.0215689 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0213072 |
| NAV3 | neuron navigator 3 | -0.0210829 |
| GSN | gelsolin | -0.0206411 |
| TRIM2 | tripartite motif containing 2 | -0.0205833 |
| RPS12 | ribosomal protein S12 | -0.0204856 |
| MFSD12 | major facilitator superfamily domain containing 12 | -0.0204811 |
| LMNA | lamin A/C | -0.0197965 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.019616 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0195918 |
| NLGN1 | neuroligin 1 | -0.0194007 |
| S100A6 | S100 calcium binding protein A6 | -0.0193478 |
| RPS6 | ribosomal protein S6 | -0.0192877 |
| CALU | calumenin | -0.0192677 |
| CAVIN1 | caveolae associated protein 1 | -0.0191209 |
| CUX1 | cut-like homeobox 1 | -0.0190565 |
| RPL19 | ribosomal protein L19 | -0.0187044 |
| TMEM123 | transmembrane protein 123 | -0.0184012 |
| RPS19 | ribosomal protein S19 | -0.0182766 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0181573 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0181429 |
| RPL26 | ribosomal protein L26 | -0.0179285 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0178702 |
| RPS3 | ribosomal protein S3 | -0.0177938 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0177339 |
| HLA-A | major histocompatibility complex, class I, A | -0.0177159 |
| RPL34 | ribosomal protein L34 | -0.0175785 |
| RPL35A | ribosomal protein L35a | -0.0175273 |
| S100A10 | S100 calcium binding protein A10 | -0.0173609 |
| GNAS | GNAS complex locus | -0.0172706 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0172442 |
| CDK14 | cyclin-dependent kinase 14 | -0.0170813 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0170094 |
| NRCAM | neuronal cell adhesion molecule | -0.016757 |
| ETV6 | ets variant 6 | -0.0165785 |
| MACROD2 | MACRO domain containing 2 | -0.0165412 |
| RPL36 | ribosomal protein L36 | -0.0165353 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0164034 |
| CCND1 | cyclin D1 | -0.0163424 |
| VGF | VGF nerve growth factor inducible | -0.0162716 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0162121 |
| FUS | FUS RNA binding protein | -0.0158767 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0157846 |
| RUNX1 | runt-related transcription factor 1 | -0.0156889 |
| NPR2 | natriuretic peptide receptor 2 | -0.015654 |
| ZNF704 | zinc finger protein 704 | -0.0155658 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0154539 |
| CALR | calreticulin | -0.0153739 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0153594 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0152366 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0150998 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0149945 |
| RPL31 | ribosomal protein L31 | -0.014935 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0149223 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0147576 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0146544 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0145295 |
| RPS20 | ribosomal protein S20 | -0.014366 |
| JAZF1 | JAZF zinc finger 1 | -0.0143036 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0141415 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0139971 |
| RPS27 | ribosomal protein S27 | -0.0138844 |
| INSIG1 | insulin induced gene 1 | -0.0138097 |
| LYST | lysosomal trafficking regulator | -0.0138079 |
| S100A9 | S100 calcium binding protein A9 | -0.0137251 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0136699 |
