| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fingolimod (hydrochloride)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.199432 |
| FNDC3B | fibronectin type III domain containing 3B | 0.148981 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.140337 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.140174 |
| NDRG1 | N-myc downstream regulated 1 | 0.130294 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.122544 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.1087 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.104881 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.100818 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0963455 |
| SMAD3 | SMAD family member 3 | 0.0908014 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0892759 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0830052 |
| UBC | ubiquitin C | 0.0814754 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0791105 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0772454 |
| TGM2 | transglutaminase 2 | 0.0770245 |
| VEGFA | vascular endothelial growth factor A | 0.0682972 |
| CCNL1 | cyclin L1 | 0.0670669 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0669723 |
| CCNY | cyclin Y | 0.0606737 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0604173 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0588662 |
| BRD2 | bromodomain containing 2 | 0.0579807 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0579317 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0578252 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0569034 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0566047 |
| APP | amyloid beta (A4) precursor protein | 0.0560668 |
| FAM13A | family with sequence similarity 13, member A | 0.0553253 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0542638 |
| POTEF | POTE ankyrin domain family, member F | 0.0541854 |
| SPAG9 | sperm associated antigen 9 | 0.0521319 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0515246 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0510696 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0507745 |
| CDCP1 | CUB domain containing protein 1 | 0.0485453 |
| HELZ | helicase with zinc finger | 0.0470118 |
| ARRDC3 | arrestin domain containing 3 | 0.0467271 |
| MCL1 | myeloid cell leukemia 1 | 0.0465675 |
| FAM3C | family with sequence similarity 3, member C | 0.0464983 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0464629 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0450152 |
| ASPH | aspartate beta-hydroxylase | 0.0444838 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0442774 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0436557 |
| PCBP2 | poly(rC) binding protein 2 | 0.0428901 |
| MATR3 | matrin 3 | 0.0427629 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0425255 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0422616 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0416718 |
| LDHA | lactate dehydrogenase A | 0.041628 |
| MYOF | myoferlin | 0.0405007 |
| ADM | adrenomedullin | 0.0397418 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0395864 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.038868 |
| APOL1 | apolipoprotein L, 1 | 0.0388135 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0387514 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0383673 |
| HPCAL1 | hippocalcin-like 1 | 0.0379743 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0378944 |
| RIOK3 | RIO kinase 3 | 0.037678 |
| EZR | ezrin | 0.0365444 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0364435 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0351193 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.034726 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0345967 |
| VMP1 | vacuole membrane protein 1 | 0.0344014 |
| PFKP | phosphofructokinase, platelet | 0.0343216 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0342801 |
| ANO6 | anoctamin 6 | 0.0339915 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0337846 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0337682 |
| PKM | pyruvate kinase, muscle | 0.0334658 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0333518 |
| NUP58 | nucleoporin 58 | 0.033248 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0331189 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0329171 |
| TPM3 | tropomyosin 3 | 0.0328977 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0327145 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0324544 |
| TMEM51 | transmembrane protein 51 | 0.0321069 |
| NOTCH2 | notch 2 | 0.0320975 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0314539 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0314334 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0312459 |
| INSIG2 | insulin induced gene 2 | 0.0303156 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0302081 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0301199 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0300702 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0299281 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0297995 |
| RUNX1 | runt-related transcription factor 1 | 0.0295669 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0293072 |
| FOSL1 | FOS-like antigen 1 | 0.0292936 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0288964 |
| SFTPA2 | surfactant protein A2 | 0.0288299 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0285805 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0283167 |
| MEF2A | myocyte enhancer factor 2A | 0.0282405 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.152231 |
| LAMB3 | laminin, beta 3 | -0.136698 |
| MMP7 | matrix metallopeptidase 7 | -0.0978532 |
| PTMA | prothymosin, alpha | -0.0727963 |
| HLA-B | major histocompatibility complex, class I, B | -0.0711005 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0701931 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0644334 |
| LMO7 | LIM domain 7 | -0.0611437 |
| RASAL2 | RAS protein activator like 2 | -0.0599041 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0571699 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0559943 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0557563 |
| CP | ceruloplasmin (ferroxidase) | -0.0540395 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0510864 |
| FTL | ferritin, light polypeptide | -0.0505734 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0493201 |
| S100A6 | S100 calcium binding protein A6 | -0.0483987 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0479395 |
| EHBP1 | EH domain binding protein 1 | -0.0477269 |
| MT2A | metallothionein 2A | -0.0473409 |
| RPS8 | ribosomal protein S8 | -0.0462274 |
| NCKAP5 | NCK-associated protein 5 | -0.0438983 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0430969 |
| RNF213 | ring finger protein 213 | -0.0412597 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0397075 |
| AHNAK | AHNAK nucleoprotein | -0.0380823 |
| RPL23 | ribosomal protein L23 | -0.0370158 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0366065 |
| FRMD5 | FERM domain containing 5 | -0.0362277 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0353694 |
| DST | dystonin | -0.0351042 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0347381 |
| RRBP1 | ribosome binding protein 1 | -0.0342727 |
| NRG3 | neuregulin 3 | -0.0333812 |
| S100A10 | S100 calcium binding protein A10 | -0.0328456 |
| KLF6 | Kruppel-like factor 6 | -0.0324999 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0322237 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0319759 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0305281 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0303966 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0299733 |
| PCDH7 | protocadherin 7 | -0.0297377 |
| ERBIN | erbb2 interacting protein | -0.0293994 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0290407 |
| RANBP17 | RAN binding protein 17 | -0.0290247 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0290121 |
| RPS21 | ribosomal protein S21 | -0.0289091 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0285893 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.028368 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0282284 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0276959 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0275122 |
| RPS19 | ribosomal protein S19 | -0.0271131 |
| RPS29 | ribosomal protein S29 | -0.0269743 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0267767 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0265959 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0265948 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0265366 |
| TJP1 | tight junction protein 1 | -0.0265068 |
| ACTG1 | actin gamma 1 | -0.0264407 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0257197 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.025391 |
| SVIL | supervillin | -0.0248975 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0247475 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0246202 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0244143 |
| PRKCA | protein kinase C, alpha | -0.024335 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0237197 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0237116 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0237103 |
| ACTN4 | actinin, alpha 4 | -0.0236455 |
| RPL35A | ribosomal protein L35a | -0.022945 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0228813 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0224678 |
| S100P | S100 calcium binding protein P | -0.02242 |
| FMNL2 | formin-like 2 | -0.022402 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0223795 |
| RPLP1 | ribosomal protein, large, P1 | -0.0221867 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0221288 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.022049 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0217806 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0214722 |
| EGFR | epidermal growth factor receptor | -0.0213584 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.0212978 |
| G0S2 | G0/G1 switch 2 | -0.0212238 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0211651 |
| GLIS3 | GLIS family zinc finger 3 | -0.0211337 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.02087 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0208295 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0207739 |
| MT1X | metallothionein 1X | -0.0206967 |
| MAP1B | microtubule-associated protein 1B | -0.0205116 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0204767 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0204751 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0204377 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0201038 |
| AK1 | adenylate kinase 1 | -0.0201018 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0199941 |
| MX2 | MX dynamin-like GTPase 2 | -0.0199641 |
| HMGA2 | high mobility group AT-hook 2 | -0.0199359 |
