| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fingolimod (hydrochloride)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.104064 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0919064 |
| B2M | beta-2-microglobulin | 0.091546 |
| NDRG1 | N-myc downstream regulated 1 | 0.0694836 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0671171 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0634217 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0630343 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0630162 |
| TXNIP | thioredoxin interacting protein | 0.0621616 |
| RNF149 | ring finger protein 149 | 0.0583529 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0504715 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0489724 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0475468 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0468184 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0452328 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0443378 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0437443 |
| PTEN | phosphatase and tensin homolog | 0.0410406 |
| DSCAM | Down syndrome cell adhesion molecule | 0.039727 |
| VEGFA | vascular endothelial growth factor A | 0.0383547 |
| ABHD2 | abhydrolase domain containing 2 | 0.0381813 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0375318 |
| RNF43 | ring finger protein 43 | 0.0370464 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0364243 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.035934 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0355294 |
| MKI67 | marker of proliferation Ki-67 | 0.0350468 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0349069 |
| RPS6 | ribosomal protein S6 | 0.0347863 |
| SBF2 | SET binding factor 2 | 0.0338277 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0335953 |
| CCNL1 | cyclin L1 | 0.0334237 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0331897 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0330733 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0326399 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0321372 |
| DIAPH3 | diaphanous-related formin 3 | 0.0317393 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0317082 |
| IFNGR1 | interferon gamma receptor 1 | 0.0314759 |
| CENPF | centromere protein F, 350/400kDa | 0.0302473 |
| DENND4C | DENN/MADD domain containing 4C | 0.0295187 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0294665 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0292741 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0292264 |
| IL20RA | interleukin 20 receptor, alpha | 0.0285918 |
| EHF | ets homologous factor | 0.027892 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0270941 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.026846 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0263734 |
| AOPEP | aminopeptidase O (putative) | 0.0262721 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0260874 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.025681 |
| RBM26 | RNA binding motif protein 26 | 0.025639 |
| TJP2 | tight junction protein 2 | 0.0254741 |
| TRIM2 | tripartite motif containing 2 | 0.0252814 |
| TMEM51 | transmembrane protein 51 | 0.0251534 |
| DSPP | dentin sialophosphoprotein | 0.0251304 |
| LIMA1 | LIM domain and actin binding 1 | 0.0251137 |
| MEIS2 | Meis homeobox 2 | 0.0251032 |
| GRAMD2B | GRAM domain containing 2B | 0.0250033 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0248519 |
| XPO1 | exportin 1 | 0.0248381 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0243665 |
| DSTN | destrin (actin depolymerizing factor) | 0.0243228 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0242969 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0242473 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0241367 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0240232 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0236309 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0232782 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0230064 |
| ZNF395 | zinc finger protein 395 | 0.0229539 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0227176 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0225833 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0225288 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.0224854 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0223356 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0221398 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0221302 |
| NUCB2 | nucleobindin 2 | 0.0217996 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0216062 |
| RUNX1 | runt-related transcription factor 1 | 0.0214237 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0213478 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.021226 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.021171 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0211269 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0209252 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.020824 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | 0.020805 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0207636 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0207325 |
| DNM2 | dynamin 2 | 0.0206435 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.0206353 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0205195 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0203106 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0203044 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0200034 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.019947 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0197918 |
| GOLGA4 | golgin A4 | 0.0196366 |
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | -0.200167 |
| ANXA2 | annexin A2 | -0.10939 |
| PLSCR2 | phospholipid scramblase 2 | -0.101101 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0991197 |
| RNF213 | ring finger protein 213 | -0.0944193 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0943027 |
| VCL | vinculin | -0.091197 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0892472 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0855876 |
| EXT1 | exostosin glycosyltransferase 1 | -0.080924 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.079889 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0790963 |
| SP100 | SP100 nuclear antigen | -0.0788212 |
| RIGI | RNA sensor RIG-I | -0.0784533 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0774884 |
| LMO7 | LIM domain 7 | -0.0756861 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0752965 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0696258 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0682638 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0665981 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0665394 |
| XAF1 | XIAP associated factor 1 | -0.0593718 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.05801 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0579483 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0566787 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0566773 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0559058 |
| MUC20 | mucin 20, cell surface associated | -0.055872 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.053816 |
| PLSCR1 | phospholipid scramblase 1 | -0.0535242 |
| SQSTM1 | sequestosome 1 | -0.0534722 |
| EGR1 | early growth response 1 | -0.0517794 |
| POU2F2 | POU class 2 homeobox 2 | -0.0516529 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0515396 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.049946 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0491417 |
| MX1 | MX dynamin-like GTPase 1 | -0.0488084 |
| LYZ | lysozyme | -0.0479511 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0469437 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0468932 |
| PHF3 | PHD finger protein 3 | -0.0464789 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0461116 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0461039 |
| NPSR1 | neuropeptide S receptor 1 | -0.0458525 |
| POF1B | premature ovarian failure, 1B | -0.0450433 |
| AREG | amphiregulin | -0.0444223 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0443644 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0442413 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0433029 |
| TJP1 | tight junction protein 1 | -0.0431533 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0429339 |
| SDC4 | syndecan 4 | -0.0428037 |
| MAP7 | microtubule-associated protein 7 | -0.042467 |
| UBAP2 | ubiquitin associated protein 2 | -0.0407034 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0400436 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0399727 |
| ACTG1 | actin gamma 1 | -0.0390748 |
| MX2 | MX dynamin-like GTPase 2 | -0.0390612 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | -0.0387635 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0387442 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0378513 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.03762 |
| SMAD3 | SMAD family member 3 | -0.0368595 |
| MCL1 | myeloid cell leukemia 1 | -0.0364171 |
| NABP1 | nucleic acid binding protein 1 | -0.0355033 |
| SETX | senataxin | -0.0349759 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0343007 |
| MCU | mitochondrial calcium uniporter | -0.0341861 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0339805 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0335248 |
| PMP22 | peripheral myelin protein 22 | -0.0333477 |
| EZR | ezrin | -0.033142 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0327793 |
| PERP | PERP, TP53 apoptosis effector | -0.0321964 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0320512 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0320388 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0316136 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0311852 |
| TNS4 | tensin 4 | -0.0307559 |
| LRRC8A | leucine rich repeat containing 8 family, member A | -0.0302334 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0300488 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0290677 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0287737 |
| TUFT1 | tuftelin 1 | -0.0287674 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0285919 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0284118 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0278819 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0277767 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0274511 |
| FBXO39 | F-box protein 39 | -0.0274373 |
| USP53 | ubiquitin specific peptidase 53 | -0.0273637 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0272354 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0270179 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0268732 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0268433 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0267842 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0265334 |
| ARF1 | ADP-ribosylation factor 1 | -0.0263013 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0260942 |
| HM13 | histocompatibility (minor) 13 | -0.0259506 |
