| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fingolimod (hydrochloride)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.15282 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.124998 |
| ASPH | aspartate beta-hydroxylase | 0.116689 |
| PAX8 | paired box 8 | 0.109776 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.101816 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0912671 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0906985 |
| LAMC2 | laminin, gamma 2 | 0.08706 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0868249 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0834291 |
| ITGB8 | integrin, beta 8 | 0.0816727 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0779039 |
| LAMB3 | laminin, beta 3 | 0.0761909 |
| POTEF | POTE ankyrin domain family, member F | 0.0759334 |
| APP | amyloid beta (A4) precursor protein | 0.0754111 |
| HELZ | helicase with zinc finger | 0.0746202 |
| PRELID2 | PRELI domain containing 2 | 0.0733838 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0719044 |
| ENO1 | enolase 1, (alpha) | 0.0707908 |
| MYOF | myoferlin | 0.0707499 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0706593 |
| FLNB | filamin B, beta | 0.0672991 |
| LDHA | lactate dehydrogenase A | 0.0661395 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0651224 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0648198 |
| VCAN | versican | 0.0647263 |
| ANXA2 | annexin A2 | 0.06367 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0636209 |
| PGK1 | phosphoglycerate kinase 1 | 0.0573015 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0570844 |
| EGFR | epidermal growth factor receptor | 0.0557517 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0529856 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0527021 |
| KRT7 | keratin 7, type II | 0.0526554 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0525189 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0523757 |
| YEATS2 | YEATS domain containing 2 | 0.0481496 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0471821 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0467639 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0461027 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0459871 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0456692 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.045586 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0455336 |
| SBF2 | SET binding factor 2 | 0.0448079 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0430246 |
| ZNF292 | zinc finger protein 292 | 0.0426623 |
| AFF1 | AF4/FMR2 family, member 1 | 0.042094 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0418129 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0417382 |
| INSIG2 | insulin induced gene 2 | 0.0414603 |
| PKM | pyruvate kinase, muscle | 0.0408726 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0408039 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0405161 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0404834 |
| FMNL2 | formin-like 2 | 0.0403476 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | 0.0401143 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0394325 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0391892 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0391432 |
| ANXA3 | annexin A3 | 0.0386835 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0384919 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | 0.0380437 |
| CANX | calnexin | 0.0378553 |
| CD2AP | CD2-associated protein | 0.037094 |
| FAM13B | family with sequence similarity 13, member B | 0.0369506 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0364966 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0362035 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0357807 |
| SLTM | SAFB-like, transcription modulator | 0.0356179 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0353743 |
| TRIM2 | tripartite motif containing 2 | 0.0352935 |
| DSG2 | desmoglein 2 | 0.0347232 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0346775 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0342423 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0340573 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0336609 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0335191 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0333134 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0328661 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.032622 |
| VEGFA | vascular endothelial growth factor A | 0.031932 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0318695 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0318669 |
| RAD51B | RAD51 paralog B | 0.0318514 |
| FNIP1 | folliculin interacting protein 1 | 0.0318445 |
| ARFGEF3 | ARFGEF family member 3 | 0.0315424 |
| TPM4 | tropomyosin 4 | 0.0311879 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | 0.0309384 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0309117 |
| TPD52 | tumor protein D52 | 0.0307288 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0304847 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0304036 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0302895 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0301802 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0300606 |
| RPL3 | ribosomal protein L3 | 0.0300335 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0299055 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0296454 |
| SQSTM1 | sequestosome 1 | 0.0295798 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL35A | ribosomal protein L35a | -0.0715925 |
| RPL9 | ribosomal protein L9 | -0.0698625 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0689841 |
| RPL23 | ribosomal protein L23 | -0.0688411 |
| RPL26 | ribosomal protein L26 | -0.0635106 |
| RPS12 | ribosomal protein S12 | -0.0620343 |
| RPS8 | ribosomal protein S8 | -0.05959 |
| RPS19 | ribosomal protein S19 | -0.0552997 |
| RPLP2 | ribosomal protein, large, P2 | -0.0534878 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0534713 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0522823 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0486613 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0482788 |
| RPL19 | ribosomal protein L19 | -0.0449307 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0433924 |
| HMGB1 | high mobility group box 1 | -0.0417799 |
| RPLP1 | ribosomal protein, large, P1 | -0.0398593 |
| MKI67 | marker of proliferation Ki-67 | -0.038061 |
| RPL37A | ribosomal protein L37a | -0.0377638 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0374115 |
| RPL28 | ribosomal protein L28 | -0.036015 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0353722 |
| RPL11 | ribosomal protein L11 | -0.0348074 |
| ACTG1 | actin gamma 1 | -0.0345107 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0335558 |
| RPS29 | ribosomal protein S29 | -0.0334992 |
| S100A10 | S100 calcium binding protein A10 | -0.0334345 |
| MACROD2 | MACRO domain containing 2 | -0.033387 |
| WWOX | WW domain containing oxidoreductase | -0.0330513 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0329619 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0324341 |
| RPL12 | ribosomal protein L12 | -0.0319168 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0306156 |
| TJP1 | tight junction protein 1 | -0.0304832 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0298361 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0292134 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0291417 |
| DIAPH3 | diaphanous-related formin 3 | -0.0289555 |
| RPS27A | ribosomal protein S27a | -0.0288307 |
| RPS21 | ribosomal protein S21 | -0.0285007 |
| RPS17 | ribosomal protein S17 | -0.0283321 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0276981 |
| RPS24 | ribosomal protein S24 | -0.02694 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.026281 |
| RPL5 | ribosomal protein L5 | -0.0261218 |
| RPL30 | ribosomal protein L30 | -0.0260352 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.025424 |
| RPL36 | ribosomal protein L36 | -0.0253834 |
| DEK | DEK proto-oncogene | -0.0253475 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0252151 |
| RPS20 | ribosomal protein S20 | -0.0249534 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0245073 |
| RPS25 | ribosomal protein S25 | -0.0243025 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0242647 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0241758 |
| CENPP | centromere protein P | -0.0238802 |
| RPL31 | ribosomal protein L31 | -0.0238401 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0237007 |
| RPS11 | ribosomal protein S11 | -0.0234564 |
| RPL34 | ribosomal protein L34 | -0.0233913 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0233108 |
| PKP4 | plakophilin 4 | -0.0233068 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0231856 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0227136 |
| EVI5 | ecotropic viral integration site 5 | -0.0226977 |
| SHTN1 | shootin 1 | -0.0226544 |
| RPS16 | ribosomal protein S16 | -0.0225794 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0224861 |
| RPL32 | ribosomal protein L32 | -0.0219194 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0218431 |
| TUSC3 | tumor suppressor candidate 3 | -0.0217348 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0217125 |
| GPHN | gephyrin | -0.0216533 |
| ANO10 | anoctamin 10 | -0.0214099 |
| RPL18 | ribosomal protein L18 | -0.0213909 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0209414 |
| SON | SON DNA binding protein | -0.0209229 |
| RPS6 | ribosomal protein S6 | -0.020917 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0209064 |
| FAT1 | FAT atypical cadherin 1 | -0.0206891 |
| OLA1 | Obg-like ATPase 1 | -0.0206041 |
| RPS27 | ribosomal protein S27 | -0.0205586 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0203137 |
| TMSB10 | thymosin beta 10 | -0.0202883 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.020232 |
| RPS3 | ribosomal protein S3 | -0.0201411 |
| TCF12 | transcription factor 12 | -0.0201246 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0201024 |
| SPECC1 | sperm antigen with calponin homology and coiled-coil domains 1 | -0.0200831 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0200748 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0199849 |
| CAB39 | calcium binding protein 39 | -0.0198337 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.019797 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0197488 |
| GMPS | guanine monphosphate synthase | -0.0194488 |
| RPL35 | ribosomal protein L35 | -0.0194166 |
| RRM2 | ribonucleotide reductase M2 | -0.0192557 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0192058 |
| RPS4X | ribosomal protein S4, X-linked | -0.0190751 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0190705 |
