| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fingolimod (hydrochloride)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.212883 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.128923 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.102202 |
| FAM13A | family with sequence similarity 13, member A | 0.0929175 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0831547 |
| DTNA | dystrobrevin, alpha | 0.080315 |
| RPS6 | ribosomal protein S6 | 0.0685839 |
| SPAG9 | sperm associated antigen 9 | 0.0675735 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.066222 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0613403 |
| RPS2 | ribosomal protein S2 | 0.0612765 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0595734 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0576137 |
| VEGFA | vascular endothelial growth factor A | 0.056901 |
| GOLGA4 | golgin A4 | 0.0568668 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0564642 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0561781 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0549518 |
| ADM | adrenomedullin | 0.0547495 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.054473 |
| OGA | O-GlcNAcase | 0.0541008 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0540433 |
| HELZ | helicase with zinc finger | 0.0522655 |
| SEC24A | SEC24 family member A | 0.0522648 |
| PTMA | prothymosin, alpha | 0.0516264 |
| ZNF292 | zinc finger protein 292 | 0.0502354 |
| RBM39 | RNA binding motif protein 39 | 0.0483681 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0482883 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0478674 |
| ATP13A3 | ATPase type 13A3 | 0.046598 |
| SETD5 | SET domain containing 5 | 0.0462099 |
| NUP58 | nucleoporin 58 | 0.0459125 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0448883 |
| RUNX1 | runt-related transcription factor 1 | 0.0428048 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0426555 |
| RNF24 | ring finger protein 24 | 0.0426122 |
| USP3 | ubiquitin specific peptidase 3 | 0.0408022 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0397542 |
| NAV2 | neuron navigator 2 | 0.0382647 |
| HPCAL1 | hippocalcin-like 1 | 0.0374952 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0371792 |
| FLNB | filamin B, beta | 0.0367702 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0366635 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0366427 |
| WDR45B | WD repeat domain 45B | 0.0355956 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0352746 |
| NDRG1 | N-myc downstream regulated 1 | 0.0350324 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.034813 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0346778 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0343229 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0342085 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0341739 |
| NGLY1 | N-glycanase 1 | 0.0335386 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0333185 |
| CAPRIN2 | caprin family member 2 | 0.0332097 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0329125 |
| GOLT1B | golgi transport 1B | 0.0328284 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0327527 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0327386 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0327243 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0326003 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0325454 |
| TMF1 | TATA element modulatory factor 1 | 0.0322383 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0321686 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.032065 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0319027 |
| FMNL2 | formin-like 2 | 0.0318924 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0318396 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0313681 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0310277 |
| RLF | rearranged L-myc fusion | 0.0309219 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0304753 |
| SRP54 | signal recognition particle 54kDa | 0.0304147 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0304057 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0303336 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0299358 |
| MSN | moesin | 0.0299256 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0298307 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0297511 |
| SEPTIN9 | septin 9 | 0.0297026 |
| MYO1B | myosin IB | 0.0296982 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.02907 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0290238 |
| IRS2 | insulin receptor substrate 2 | 0.0288117 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0287933 |
| NOP58 | NOP58 ribonucleoprotein | 0.0284453 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0283541 |
| RNF145 | ring finger protein 145 | 0.0282063 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0279505 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.027729 |
| RPL12 | ribosomal protein L12 | 0.0275821 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0273159 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.027243 |
| MATR3 | matrin 3 | 0.0268877 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0267176 |
| RPL7 | ribosomal protein L7 | 0.0265425 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0264954 |
| RPL3 | ribosomal protein L3 | 0.0262841 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0262443 |
| QKI | QKI, KH domain containing, RNA binding | 0.0260736 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.360353 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.248198 |
| VIM | vimentin | -0.229881 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.144433 |
| TMSB10 | thymosin beta 10 | -0.0926399 |
| EGR1 | early growth response 1 | -0.0884236 |
| GLIS3 | GLIS family zinc finger 3 | -0.0838047 |
| IGF2 | insulin-like growth factor 2 | -0.0761618 |
| CD44 | CD44 molecule (Indian blood group) | -0.0756225 |
| AHNAK | AHNAK nucleoprotein | -0.0687528 |
| TENM2 | teneurin transmembrane protein 2 | -0.0685471 |
| HMGA2 | high mobility group AT-hook 2 | -0.0658967 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0646371 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0623835 |
| CDH13 | cadherin 13 | -0.0596627 |
| CCND1 | cyclin D1 | -0.05869 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0581532 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0571724 |
| DST | dystonin | -0.0571273 |
| COL1A1 | collagen, type I, alpha 1 | -0.0539263 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0538507 |
| RAI14 | retinoic acid induced 14 | -0.0527371 |
| ENO1 | enolase 1, (alpha) | -0.0525444 |
| TNNC1 | troponin C type 1 (slow) | -0.0523868 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0496153 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0492908 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0482599 |
| LOX | lysyl oxidase | -0.0482267 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0461109 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0424591 |
| MT2A | metallothionein 2A | -0.0409078 |
| COL5A1 | collagen, type V, alpha 1 | -0.0407764 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0403366 |
| VCL | vinculin | -0.0391712 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0390215 |
| FMN1 | formin 1 | -0.0375803 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0374031 |
| TXNIP | thioredoxin interacting protein | -0.0353163 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.033061 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0323553 |
| PGK1 | phosphoglycerate kinase 1 | -0.0323426 |
| BPTF | bromodomain PHD finger transcription factor | -0.0302114 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0301698 |
| ETV6 | ets variant 6 | -0.0298057 |
| RAD51B | RAD51 paralog B | -0.0296358 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0295898 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0290477 |
| POTEF | POTE ankyrin domain family, member F | -0.0287932 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0282597 |
| TUBB | tubulin, beta class I | -0.0281506 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0280921 |
| MAP1B | microtubule-associated protein 1B | -0.0280227 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0277693 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0274525 |
| RIN2 | Ras and Rab interactor 2 | -0.0273288 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0271247 |
| LDHA | lactate dehydrogenase A | -0.0268492 |
| PRSS23 | protease, serine, 23 | -0.0265281 |
| ACTG1 | actin gamma 1 | -0.026099 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.025589 |
| ANXA2 | annexin A2 | -0.0255466 |
| CANX | calnexin | -0.0249361 |
| NF1 | neurofibromin 1 | -0.0246347 |
| INHBA | inhibin, beta A | -0.0245984 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0245362 |
| MYO9A | myosin IXA | -0.0242324 |
| IL1B | interleukin 1, beta | -0.0238355 |
| ACTN4 | actinin, alpha 4 | -0.0235221 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0235178 |
| PRKCA | protein kinase C, alpha | -0.0233985 |
| TPM4 | tropomyosin 4 | -0.0232454 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0231056 |
| FTL | ferritin, light polypeptide | -0.0231035 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0230234 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0224496 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.0224433 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0223741 |
| TPM1 | tropomyosin 1 (alpha) | -0.0222803 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0222353 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.0220005 |
| KLF12 | Kruppel-like factor 12 | -0.0219784 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.02182 |
| TPI1 | triosephosphate isomerase 1 | -0.0212323 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0211939 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0209991 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0209134 |
| CDK6 | cyclin-dependent kinase 6 | -0.0206825 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.020384 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0203742 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0203506 |
| RPL35A | ribosomal protein L35a | -0.0202208 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0201581 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0200189 |
| HDLBP | high density lipoprotein binding protein | -0.0198096 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0194764 |
| OSMR | oncostatin M receptor | -0.0191522 |
| SMYD3 | SET and MYND domain containing 3 | -0.018989 |
| EHBP1 | EH domain binding protein 1 | -0.018924 |
| CAVIN1 | caveolae associated protein 1 | -0.0187776 |
| MRC2 | mannose receptor, C type 2 | -0.0187685 |
