| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fingolimod (hydrochloride)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.102111 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0615733 |
| GOLGA4 | golgin A4 | 0.0579341 |
| RPS2 | ribosomal protein S2 | 0.0453527 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.044676 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0412959 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0390858 |
| VEGFA | vascular endothelial growth factor A | 0.037973 |
| RPL21 | ribosomal protein L21 | 0.0375376 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0370756 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0345484 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0342279 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0319899 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0316992 |
| OGA | O-GlcNAcase | 0.0312345 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0307506 |
| MSN | moesin | 0.030603 |
| PTEN | phosphatase and tensin homolog | 0.0301446 |
| NUP58 | nucleoporin 58 | 0.0288362 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0286334 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0278354 |
| NDRG1 | N-myc downstream regulated 1 | 0.0275295 |
| HYOU1 | hypoxia up-regulated 1 | 0.0275001 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0272114 |
| ZNF292 | zinc finger protein 292 | 0.0271931 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0270598 |
| ERBIN | erbb2 interacting protein | 0.02691 |
| RNF145 | ring finger protein 145 | 0.0268034 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0267628 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0264897 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0264871 |
| FAM135A | family with sequence similarity 135, member A | 0.0259454 |
| SBF2 | SET binding factor 2 | 0.0253186 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0252878 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.025235 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.024927 |
| JMJD1C | jumonji domain containing 1C | 0.0248706 |
| TPM3 | tropomyosin 3 | 0.0248262 |
| CCNL1 | cyclin L1 | 0.0246318 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0245818 |
| STK24 | serine/threonine kinase 24 | 0.0245671 |
| BRD2 | bromodomain containing 2 | 0.0245447 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0242519 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0241949 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0239437 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0239142 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0238087 |
| NCKAP1 | NCK-associated protein 1 | 0.0237442 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0237174 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0237134 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0236405 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0235686 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0232532 |
| RBM39 | RNA binding motif protein 39 | 0.0231367 |
| SUCO | SUN domain containing ossification factor | 0.0229887 |
| MATR3 | matrin 3 | 0.0228433 |
| XPO1 | exportin 1 | 0.0227384 |
| PDS5B | PDS5 cohesin associated factor B | 0.0226081 |
| POTEF | POTE ankyrin domain family, member F | 0.0225681 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0225312 |
| RPL3 | ribosomal protein L3 | 0.0224605 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0223158 |
| COG5 | component of oligomeric golgi complex 5 | 0.0222579 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0222311 |
| CLTC | clathrin, heavy chain (Hc) | 0.0218225 |
| TMEM41B | transmembrane protein 41B | 0.0213319 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0212807 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0211718 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0210292 |
| KIF5B | kinesin family member 5B | 0.0207254 |
| LMO7 | LIM domain 7 | 0.0207012 |
| FNBP4 | formin binding protein 4 | 0.0206551 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0206129 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0205399 |
| HELZ | helicase with zinc finger | 0.0204754 |
| PCBP2 | poly(rC) binding protein 2 | 0.0204628 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0203882 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0203807 |
| PDZD8 | PDZ domain containing 8 | 0.0203418 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0202556 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0200782 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0200657 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0200633 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0196732 |
| CREBRF | CREB3 regulatory factor | 0.019637 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0195972 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0193184 |
| UBE3A | ubiquitin protein ligase E3A | 0.0192706 |
| CEP57 | centrosomal protein 57kDa | 0.0191654 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0191621 |
| THOC2 | THO complex 2 | 0.0190755 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0190077 |
| YTHDC1 | YTH domain containing 1 | 0.0189955 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0189465 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.018848 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0187559 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0186909 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0186187 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0184991 |
| RTN4 | reticulon 4 | 0.0183876 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH14 | myosin, heavy chain 14, non-muscle | -0.215536 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.177416 |
| KRT20 | keratin 20, type I | -0.132681 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.110494 |
| AHNAK | AHNAK nucleoprotein | -0.106658 |
| EXT1 | exostosin glycosyltransferase 1 | -0.100631 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0995404 |
| INTS6 | integrator complex subunit 6 | -0.0993199 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0983272 |
| LAMA4 | laminin, alpha 4 | -0.0981926 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0945228 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0926465 |
| KRT8 | keratin 8, type II | -0.0887379 |
| FRY | furry homolog (Drosophila) | -0.0833669 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0782508 |
| TMSB10 | thymosin beta 10 | -0.0765024 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0705968 |
| SMAD3 | SMAD family member 3 | -0.0694946 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0689279 |
| MMP7 | matrix metallopeptidase 7 | -0.0684558 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0667754 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0667645 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0653936 |
| POF1B | premature ovarian failure, 1B | -0.0646578 |
| ACTN4 | actinin, alpha 4 | -0.0638864 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0609507 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0606283 |
| ACTG1 | actin gamma 1 | -0.058573 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0569821 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0537484 |
| RPL35A | ribosomal protein L35a | -0.0537223 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0530655 |
| TRIB1 | tribbles pseudokinase 1 | -0.0526961 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0526925 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.052618 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0519385 |
| ANXA2 | annexin A2 | -0.0515081 |
| CTBP2 | C-terminal binding protein 2 | -0.0513014 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0501659 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0501361 |
| RNF213 | ring finger protein 213 | -0.0496556 |
| EGR1 | early growth response 1 | -0.0495451 |
| PGK1 | phosphoglycerate kinase 1 | -0.0495216 |
| AGR2 | anterior gradient 2 | -0.0493702 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0490334 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0485925 |
| KRT19 | keratin 19, type I | -0.0474772 |
| RPS24 | ribosomal protein S24 | -0.0473616 |
| PTMA | prothymosin, alpha | -0.0473468 |
| DIAPH2 | diaphanous-related formin 2 | -0.0472548 |
| MYO1E | myosin IE | -0.0471873 |
| KRT18 | keratin 18, type I | -0.0469562 |
| JUN | jun proto-oncogene | -0.0462643 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0457796 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.045391 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0443918 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0440071 |
| S100A10 | S100 calcium binding protein A10 | -0.0439917 |
| PRELID2 | PRELI domain containing 2 | -0.0438658 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0437341 |
| ASPH | aspartate beta-hydroxylase | -0.0422729 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0422177 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.041561 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0396668 |
| RPLP1 | ribosomal protein, large, P1 | -0.0378007 |
| VCL | vinculin | -0.0377516 |
| SDC4 | syndecan 4 | -0.0371444 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0371259 |
| MCL1 | myeloid cell leukemia 1 | -0.035478 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0354632 |
| TMEM65 | transmembrane protein 65 | -0.0353528 |
| RPL34 | ribosomal protein L34 | -0.0352585 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0352426 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0352425 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0351395 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0349852 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0341186 |
| FOXO3 | forkhead box O3 | -0.0339072 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0330025 |
| AREG | amphiregulin | -0.0328533 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0326509 |
| CAPN8 | calpain 8 | -0.0323567 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.032246 |
| RPS8 | ribosomal protein S8 | -0.0322005 |
| LMNA | lamin A/C | -0.0320791 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0319862 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.031259 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0311554 |
| RPS25 | ribosomal protein S25 | -0.0304795 |
| PRR5L | proline rich 5 like | -0.0303519 |
| CUX1 | cut-like homeobox 1 | -0.0294853 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.029096 |
| GNAS | GNAS complex locus | -0.0290051 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0289096 |
| LYZ | lysozyme | -0.0286958 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0285002 |
| TJP1 | tight junction protein 1 | -0.0281417 |
| SQSTM1 | sequestosome 1 | -0.0281299 |
| RPLP0 | ribosomal protein, large, P0 | -0.0279911 |
| GSN | gelsolin | -0.0279236 |
