| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fingolimod (hydrochloride)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.265351 |
| NDRG1 | N-myc downstream regulated 1 | 0.210727 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.199978 |
| MTSS1 | metastasis suppressor 1 | 0.144852 |
| MYOF | myoferlin | 0.116489 |
| PODXL | podocalyxin-like | 0.0991395 |
| ANXA1 | annexin A1 | 0.0986446 |
| LMO7 | LIM domain 7 | 0.0969115 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0958698 |
| MSN | moesin | 0.0931901 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0918949 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0875927 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0873985 |
| EZR | ezrin | 0.0810434 |
| POTEF | POTE ankyrin domain family, member F | 0.0760803 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0700638 |
| EMP1 | epithelial membrane protein 1 | 0.068781 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0684052 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0680571 |
| CD44 | CD44 molecule (Indian blood group) | 0.0644689 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0639034 |
| ITGA6 | integrin, alpha 6 | 0.0637042 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0632292 |
| MEF2A | myocyte enhancer factor 2A | 0.0630997 |
| ENO1 | enolase 1, (alpha) | 0.0625534 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0620208 |
| ANXA2 | annexin A2 | 0.0618752 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0597687 |
| RAI14 | retinoic acid induced 14 | 0.0586833 |
| RBM39 | RNA binding motif protein 39 | 0.0574766 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0563827 |
| PLEC | plectin | 0.0560008 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0542562 |
| PGK1 | phosphoglycerate kinase 1 | 0.0537991 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0529715 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0526713 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0519345 |
| LAMC2 | laminin, gamma 2 | 0.0506956 |
| MYO10 | myosin X | 0.0500132 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0495393 |
| BCL2L1 | BCL2-like 1 | 0.0492382 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0486019 |
| VCL | vinculin | 0.0483438 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0475939 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0475824 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0472768 |
| RIN2 | Ras and Rab interactor 2 | 0.0470383 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0468753 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0468217 |
| PLS3 | plastin 3 | 0.0458562 |
| CUL4B | cullin 4B | 0.0446473 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0444724 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0433776 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0430211 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0424644 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0418069 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0417346 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0417018 |
| GOLGA4 | golgin A4 | 0.0407621 |
| TSC22D1 | TSC22 domain family, member 1 | 0.040623 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.0403404 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0400613 |
| TPM3 | tropomyosin 3 | 0.0397545 |
| FNIP1 | folliculin interacting protein 1 | 0.0396211 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0395332 |
| MCL1 | myeloid cell leukemia 1 | 0.0393765 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0391379 |
| CANX | calnexin | 0.038459 |
| TGM2 | transglutaminase 2 | 0.0374149 |
| SQLE | squalene epoxidase | 0.0369321 |
| LDHA | lactate dehydrogenase A | 0.0368214 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0367711 |
| SMAD3 | SMAD family member 3 | 0.0365249 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.036097 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0360873 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0359769 |
| SLK | STE20-like kinase | 0.0358207 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0357726 |
| OGA | O-GlcNAcase | 0.0356341 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.035325 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0347104 |
| CDK6 | cyclin-dependent kinase 6 | 0.0343801 |
| PLK2 | polo-like kinase 2 | 0.0343672 |
| RASAL2 | RAS protein activator like 2 | 0.0343146 |
| CMIP | c-Maf inducing protein | 0.0342564 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0339224 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0337983 |
| RND3 | Rho family GTPase 3 | 0.0336624 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.033368 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0333639 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0330237 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0328569 |
| BLCAP | bladder cancer associated protein | 0.0328567 |
| APP | amyloid beta (A4) precursor protein | 0.0328053 |
| FOXO1 | forkhead box O1 | 0.0327899 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0325971 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0324953 |
| RUNX1 | runt-related transcription factor 1 | 0.0323799 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0322631 |
| SUCO | SUN domain containing ossification factor | 0.0321995 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.117681 |
| RPLP2 | ribosomal protein, large, P2 | -0.0696241 |
| MT2A | metallothionein 2A | -0.0685387 |
| PTMA | prothymosin, alpha | -0.0583532 |
| TMSB10 | thymosin beta 10 | -0.0533112 |
| RPS21 | ribosomal protein S21 | -0.0491636 |
| RPS8 | ribosomal protein S8 | -0.0483816 |
| HLA-B | major histocompatibility complex, class I, B | -0.0458449 |
| RPS19 | ribosomal protein S19 | -0.0451254 |
| RPLP1 | ribosomal protein, large, P1 | -0.0428622 |
| RPL23 | ribosomal protein L23 | -0.0426969 |
| RPS24 | ribosomal protein S24 | -0.0401756 |
| RPL35A | ribosomal protein L35a | -0.0392558 |
| RPL12 | ribosomal protein L12 | -0.0385666 |
| RPS6 | ribosomal protein S6 | -0.0357387 |
| RPS12 | ribosomal protein S12 | -0.0356258 |
| MT1X | metallothionein 1X | -0.0345814 |
| RPS25 | ribosomal protein S25 | -0.0329424 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.032829 |
| B2M | beta-2-microglobulin | -0.0323487 |
| RPL11 | ribosomal protein L11 | -0.0312268 |
| RPS3 | ribosomal protein S3 | -0.0307148 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0302051 |
| RPL30 | ribosomal protein L30 | -0.0297337 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0294885 |
| FTL | ferritin, light polypeptide | -0.028693 |
| RPL31 | ribosomal protein L31 | -0.0281449 |
| RPL19 | ribosomal protein L19 | -0.0280289 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0277939 |
| RPL36 | ribosomal protein L36 | -0.027786 |
| RPL36A | ribosomal protein L36a | -0.0276963 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0276405 |
| RPL9 | ribosomal protein L9 | -0.0270273 |
| RPS13 | ribosomal protein S13 | -0.0266303 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0259308 |
| RPL37A | ribosomal protein L37a | -0.0252745 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0249845 |
| RPL26 | ribosomal protein L26 | -0.0248603 |
| RPL34 | ribosomal protein L34 | -0.0242453 |
| RPS27A | ribosomal protein S27a | -0.023814 |
| RPS23 | ribosomal protein S23 | -0.0235535 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0234515 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0230546 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0227585 |
| RPL32 | ribosomal protein L32 | -0.0225615 |
| RPL35 | ribosomal protein L35 | -0.0222821 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0216902 |
| RPL27A | ribosomal protein L27a | -0.0214587 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0213083 |
| RPS29 | ribosomal protein S29 | -0.0210741 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0208429 |
| S100A6 | S100 calcium binding protein A6 | -0.0205659 |
| RPLP0 | ribosomal protein, large, P0 | -0.0204996 |
| S100A2 | S100 calcium binding protein A2 | -0.0204326 |
| S100A10 | S100 calcium binding protein A10 | -0.0200799 |
| HMGB1 | high mobility group box 1 | -0.019595 |
| RPL21 | ribosomal protein L21 | -0.0193271 |
| RPS27 | ribosomal protein S27 | -0.0193229 |
| RPS14 | ribosomal protein S14 | -0.0186625 |
| STC1 | stanniocalcin 1 | -0.0186146 |
| GUK1 | guanylate kinase 1 | -0.0183699 |
| RPL8 | ribosomal protein L8 | -0.0179056 |
| RPS4X | ribosomal protein S4, X-linked | -0.0177365 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0172709 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0169764 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.0168936 |
| RPS16 | ribosomal protein S16 | -0.016613 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.016189 |
| ROMO1 | reactive oxygen species modulator 1 | -0.0161119 |
| S100A9 | S100 calcium binding protein A9 | -0.016018 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0159741 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0157311 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0156032 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0152278 |
| HLA-A | major histocompatibility complex, class I, A | -0.0152247 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0149923 |
| RPL18 | ribosomal protein L18 | -0.0146076 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0145981 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0145659 |
| COX7B | cytochrome c oxidase subunit VIIb | -0.0144537 |
| MGP | matrix Gla protein | -0.0143714 |
| S100A4 | S100 calcium binding protein A4 | -0.0142635 |
| RPL27 | ribosomal protein L27 | -0.0138946 |
| RPL37 | ribosomal protein L37 | -0.013842 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -0.0137195 |
| CBX3 | chromobox homolog 3 | -0.0136394 |
| ATP5MK | ATP synthase membrane subunit k | -0.013609 |
| POMP | proteasome maturation protein | -0.013571 |
| IER3 | immediate early response 3 | -0.0135107 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.0132949 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0131217 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0130706 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.0130696 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0130252 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0129822 |
| ATP5MG | ATP synthase membrane subunit g | -0.0129754 |
| RDX | radixin | -0.0129625 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0129296 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0128425 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0128074 |
