| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fingolimod (hydrochloride)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.23116 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.108355 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.108024 |
| ATP13A3 | ATPase type 13A3 | 0.0941714 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0932519 |
| ADM | adrenomedullin | 0.0786504 |
| NDRG1 | N-myc downstream regulated 1 | 0.0750118 |
| POTEF | POTE ankyrin domain family, member F | 0.0715541 |
| SLC12A8 | solute carrier family 12, member 8 | 0.0707915 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0635815 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0600052 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0580278 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0542445 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0535036 |
| NUP58 | nucleoporin 58 | 0.0519647 |
| B2M | beta-2-microglobulin | 0.0500817 |
| TPD52 | tumor protein D52 | 0.0498905 |
| ANXA1 | annexin A1 | 0.0490212 |
| TXNRD1 | thioredoxin reductase 1 | 0.0476718 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0469413 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0467852 |
| PLK2 | polo-like kinase 2 | 0.0462395 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0462104 |
| SMAD3 | SMAD family member 3 | 0.0441406 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0425253 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0422177 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0421248 |
| FOSL1 | FOS-like antigen 1 | 0.0419669 |
| MSN | moesin | 0.0419653 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0417452 |
| PCBP2 | poly(rC) binding protein 2 | 0.041062 |
| SPAG9 | sperm associated antigen 9 | 0.04023 |
| CCNL1 | cyclin L1 | 0.0396505 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0391366 |
| SET | SET nuclear proto-oncogene | 0.0387658 |
| TPM3 | tropomyosin 3 | 0.038413 |
| PDS5B | PDS5 cohesin associated factor B | 0.0375918 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0368267 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0368131 |
| SUCO | SUN domain containing ossification factor | 0.0362664 |
| GOLGA4 | golgin A4 | 0.0355595 |
| ZNF292 | zinc finger protein 292 | 0.0354683 |
| TGFB2 | transforming growth factor, beta 2 | 0.0353218 |
| TPX2 | TPX2, microtubule-associated | 0.0352082 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0350927 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0348337 |
| NUP153 | nucleoporin 153kDa | 0.0348105 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0347392 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0345507 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0341774 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0334875 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0333954 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0333631 |
| ARF4 | ADP-ribosylation factor 4 | 0.0326382 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0323862 |
| RIOK3 | RIO kinase 3 | 0.03235 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.032071 |
| NOP58 | NOP58 ribonucleoprotein | 0.0317513 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0316761 |
| TFG | TRK-fused gene | 0.0315881 |
| CALR | calreticulin | 0.0313267 |
| ZNF841 | zinc finger protein 841 | 0.0308305 |
| GRAMD2B | GRAM domain containing 2B | 0.0299776 |
| TMF1 | TATA element modulatory factor 1 | 0.0295322 |
| HELZ | helicase with zinc finger | 0.0293218 |
| SEC24A | SEC24 family member A | 0.02925 |
| UBC | ubiquitin C | 0.0291555 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0288438 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0287894 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0284167 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0282173 |
| ANO6 | anoctamin 6 | 0.0282099 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0282067 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0279204 |
| FLNB | filamin B, beta | 0.0278635 |
| SRP54 | signal recognition particle 54kDa | 0.0277989 |
| CKAP5 | cytoskeleton associated protein 5 | 0.027736 |
| DENND4C | DENN/MADD domain containing 4C | 0.027243 |
| IPO7 | importin 7 | 0.0269551 |
| ECT2 | epithelial cell transforming 2 | 0.0267361 |
| CENPF | centromere protein F, 350/400kDa | 0.0263628 |
| VEGFA | vascular endothelial growth factor A | 0.0258402 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0253277 |
| HPS3 | Hermansky-Pudlak syndrome 3 | 0.0249964 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0249821 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0249696 |
| UBQLN1 | ubiquilin 1 | 0.0249533 |
| USP3 | ubiquitin specific peptidase 3 | 0.0248953 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0246806 |
| ANLN | anillin, actin binding protein | 0.0242653 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0241256 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0239985 |
| NCKAP1 | NCK-associated protein 1 | 0.0235161 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0234296 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0234124 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0233924 |
| FAM219A | family with sequence similarity 219, member A | 0.0233599 |
| ARRDC3 | arrestin domain containing 3 | 0.0232921 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0231813 |
| RLF | rearranged L-myc fusion | 0.0231373 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.295993 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.204907 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.166785 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.142714 |
| EXT1 | exostosin glycosyltransferase 1 | -0.118844 |
| MT2A | metallothionein 2A | -0.0916826 |
| ASPH | aspartate beta-hydroxylase | -0.0912342 |
| HLA-B | major histocompatibility complex, class I, B | -0.090438 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0846654 |
| AHNAK | AHNAK nucleoprotein | -0.0825681 |
| VIM | vimentin | -0.0750413 |
| INTS6 | integrator complex subunit 6 | -0.0711804 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.063444 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0615005 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0611377 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0591281 |
| TMSB10 | thymosin beta 10 | -0.0580971 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0566576 |
| RPL35A | ribosomal protein L35a | -0.0557054 |
| SMYD3 | SET and MYND domain containing 3 | -0.0534537 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0512764 |
| GLIS3 | GLIS family zinc finger 3 | -0.0498423 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0494406 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0493639 |
| ZNF804A | zinc finger protein 804A | -0.0489552 |
| CAVIN1 | caveolae associated protein 1 | -0.0480504 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0447133 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0445174 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0421847 |
| TLE4 | transducin-like enhancer of split 4 | -0.0421239 |
| PRELID2 | PRELI domain containing 2 | -0.0405028 |
| RPS6 | ribosomal protein S6 | -0.0403971 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0400563 |
| RPLP2 | ribosomal protein, large, P2 | -0.0387465 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0383708 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0376614 |
| CD44 | CD44 molecule (Indian blood group) | -0.0368791 |
| PLSCR1 | phospholipid scramblase 1 | -0.0367465 |
| VCL | vinculin | -0.0360049 |
| RPL23 | ribosomal protein L23 | -0.0351787 |
| ANXA2 | annexin A2 | -0.0345006 |
| RIGI | RNA sensor RIG-I | -0.0341127 |
| RPL37 | ribosomal protein L37 | -0.0340601 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0339848 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0339002 |
| RAD51B | RAD51 paralog B | -0.0336352 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0335393 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0332847 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.03328 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0332775 |
| RPS8 | ribosomal protein S8 | -0.0332364 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0327588 |
| FHIT | fragile histidine triad | -0.0327305 |
| E2F3 | E2F transcription factor 3 | -0.0325902 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0322099 |
| PTMA | prothymosin, alpha | -0.0321154 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0317338 |
| SP100 | SP100 nuclear antigen | -0.0316959 |
| AEBP2 | AE binding protein 2 | -0.0316088 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0313798 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0310219 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0306795 |
| DTNA | dystrobrevin, alpha | -0.0298384 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | -0.0295537 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0294395 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0292877 |
| ACTG1 | actin gamma 1 | -0.0287882 |
| OSMR | oncostatin M receptor | -0.0287803 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0287176 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0286868 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0285837 |
| DPYD | dihydropyrimidine dehydrogenase | -0.028579 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0284881 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0284246 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0283321 |
| RPS19 | ribosomal protein S19 | -0.0282632 |
| RPL26 | ribosomal protein L26 | -0.0278971 |
| KLF12 | Kruppel-like factor 12 | -0.0275492 |
| RPS24 | ribosomal protein S24 | -0.0274664 |
| RPLP1 | ribosomal protein, large, P1 | -0.0270429 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0265894 |
| RPL31 | ribosomal protein L31 | -0.0262934 |
| WNT5B | wingless-type MMTV integration site family, member 5B | -0.0262173 |
| TBCA | tubulin folding cofactor A | -0.0262064 |
| CAST | calpastatin | -0.0261964 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0260175 |
| GNAS | GNAS complex locus | -0.0259788 |
| BPTF | bromodomain PHD finger transcription factor | -0.0257189 |
| RPL34 | ribosomal protein L34 | -0.0257023 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0254748 |
| HMGB1 | high mobility group box 1 | -0.025239 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0251221 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0249916 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0245103 |
| NAV1 | neuron navigator 1 | -0.0244628 |
| WWOX | WW domain containing oxidoreductase | -0.0242829 |
| PDLIM5 | PDZ and LIM domain 5 | -0.024181 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0241687 |
| DENND1A | DENN/MADD domain containing 1A | -0.0241609 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0240963 |
