| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fingolimod (hydrochloride)_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAML2 | mastermind-like 2 (Drosophila) | 0.126343 |
| NPSR1 | neuropeptide S receptor 1 | 0.109737 |
| RPS6 | ribosomal protein S6 | 0.10602 |
| VEGFA | vascular endothelial growth factor A | 0.087069 |
| NDRG1 | N-myc downstream regulated 1 | 0.0763217 |
| GOLGA4 | golgin A4 | 0.0754098 |
| POTEF | POTE ankyrin domain family, member F | 0.0694301 |
| RPS2 | ribosomal protein S2 | 0.0642061 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0556634 |
| FTL | ferritin, light polypeptide | 0.0539166 |
| AREG | amphiregulin | 0.0527927 |
| RPL35A | ribosomal protein L35a | 0.0516842 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0511349 |
| LCN2 | lipocalin 2 | 0.0483944 |
| ITGA6 | integrin, alpha 6 | 0.0480306 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0465818 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0456268 |
| RBM39 | RNA binding motif protein 39 | 0.0447814 |
| ANXA1 | annexin A1 | 0.0402436 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0380665 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0379274 |
| FAM13A | family with sequence similarity 13, member A | 0.0365409 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0354575 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0349515 |
| AGR3 | anterior gradient 3 | 0.0347144 |
| PTMA | prothymosin, alpha | 0.0345785 |
| DSTN | destrin (actin depolymerizing factor) | 0.034032 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0338494 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0327656 |
| KLHL29 | kelch-like family member 29 | 0.0327207 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0323699 |
| RPS19 | ribosomal protein S19 | 0.0319483 |
| SETD5 | SET domain containing 5 | 0.0316173 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0315612 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0315581 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0312095 |
| S100A9 | S100 calcium binding protein A9 | 0.0311267 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0309879 |
| RPS21 | ribosomal protein S21 | 0.0299826 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0296565 |
| KRT19 | keratin 19, type I | 0.0295443 |
| MORF4L2 | mortality factor 4 like 2 | 0.0289908 |
| ATF4 | activating transcription factor 4 | 0.0289614 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0287711 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0286763 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0285831 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0282634 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0276675 |
| S100A6 | S100 calcium binding protein A6 | 0.027353 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0272107 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0271164 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0262713 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0259882 |
| RPS25 | ribosomal protein S25 | 0.0254008 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0251823 |
| RPL27 | ribosomal protein L27 | 0.0246597 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0244818 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0241691 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0241006 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0240828 |
| ATF5 | activating transcription factor 5 | 0.0240669 |
| CUX1 | cut-like homeobox 1 | 0.0240118 |
| SERF2 | small EDRK-rich factor 2 | 0.024011 |
| AUTS2 | autism susceptibility candidate 2 | 0.0238641 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0236271 |
| TMSB10 | thymosin beta 10 | 0.0231357 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0230301 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 0.0229071 |
| RPS16 | ribosomal protein S16 | 0.0228776 |
| CCNY | cyclin Y | 0.0226819 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0225807 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0224914 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0222582 |
| HELZ | helicase with zinc finger | 0.0219764 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0218289 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0214308 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | 0.0211334 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0210256 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0210053 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0209203 |
| PFN1 | profilin 1 | 0.0203992 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0203326 |
| HMGA1 | high mobility group AT-hook 1 | 0.0200925 |
| TFF2 | trefoil factor 2 | 0.0200021 |
| RPL38 | ribosomal protein L38 | 0.0198344 |
| PKM | pyruvate kinase, muscle | 0.0197961 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.019653 |
| S100P | S100 calcium binding protein P | 0.0195922 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0194008 |
| WDR45B | WD repeat domain 45B | 0.0192889 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0191559 |
| B2M | beta-2-microglobulin | 0.0191196 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0188773 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0187349 |
| SPAG9 | sperm associated antigen 9 | 0.0187154 |
| GOLGB1 | golgin B1 | 0.0185805 |
| PGM3 | phosphoglucomutase 3 | 0.0185174 |
| SRP54 | signal recognition particle 54kDa | 0.0184769 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.017803 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.017722 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.163706 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.091937 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0870521 |
| UBC | ubiquitin C | -0.0868936 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0834615 |
| AHNAK | AHNAK nucleoprotein | -0.0813706 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0581783 |
| KRT8 | keratin 8, type II | -0.0522252 |
| RPS27A | ribosomal protein S27a | -0.0431338 |
| HLA-E | major histocompatibility complex, class I, E | -0.0424165 |
| TMC5 | transmembrane channel-like 5 | -0.0396374 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0328107 |
| TXNRD1 | thioredoxin reductase 1 | -0.0290103 |
| AHR | aryl hydrocarbon receptor | -0.0287455 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0278029 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.027614 |
| JUN | jun proto-oncogene | -0.0271828 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0266839 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0255635 |
| PLSCR1 | phospholipid scramblase 1 | -0.0255453 |
| CDK12 | cyclin-dependent kinase 12 | -0.0240878 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0239972 |
| CANX | calnexin | -0.023616 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0236033 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0231491 |
| EPCAM | epithelial cell adhesion molecule | -0.0231141 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0228597 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0214629 |
| ECT2 | epithelial cell transforming 2 | -0.021174 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0209252 |
| CALU | calumenin | -0.020797 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0203502 |
| STK24 | serine/threonine kinase 24 | -0.0197314 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0196183 |
| ANXA2 | annexin A2 | -0.0196124 |
| VMP1 | vacuole membrane protein 1 | -0.0193062 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0190937 |
| PRSS3 | protease, serine, 3 | -0.0185536 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0182823 |
| ACTN4 | actinin, alpha 4 | -0.0180489 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0176094 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0168323 |
| ALDOC | aldolase C, fructose-bisphosphate | -0.0167919 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0164998 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0164199 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0158705 |
| ENO1 | enolase 1, (alpha) | -0.0157507 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0157167 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0156233 |
| CAPN8 | calpain 8 | -0.015403 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | -0.0152318 |
| LMO7 | LIM domain 7 | -0.0152187 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0152181 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0151154 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0150628 |
| KRT17 | keratin 17, type I | -0.0149113 |
| TMEM45B | transmembrane protein 45B | -0.0147227 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 | -0.0146921 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0145379 |
| PCBP2 | poly(rC) binding protein 2 | -0.0144543 |
| EMP1 | epithelial membrane protein 1 | -0.0143823 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.014244 |
| ASPH | aspartate beta-hydroxylase | -0.014233 |
| TRIB1 | tribbles pseudokinase 1 | -0.0141603 |
| SEPTIN9 | septin 9 | -0.0139148 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0138507 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0138139 |
| RNF169 | ring finger protein 169 | -0.0137542 |
| APP | amyloid beta (A4) precursor protein | -0.013746 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0137229 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0136392 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0135356 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0133006 |
| CD2AP | CD2-associated protein | -0.0132916 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0131988 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0131908 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0130855 |
| ATM | ATM serine/threonine kinase | -0.0129984 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0129869 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.012971 |
| RPN1 | ribophorin I | -0.0129374 |
| H1-0 | H1.0 linker histone | -0.0129123 |
| RPL23 | ribosomal protein L23 | -0.0128664 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0127814 |
| PLEC | plectin | -0.012759 |
| CD164 | CD164 molecule, sialomucin | -0.0126015 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0125603 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.012422 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0123427 |
| EXPH5 | exophilin 5 | -0.0123405 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0122307 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0120328 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0120284 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0120165 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0119958 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0119832 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0119763 |
| ABHD17C | abhydrolase domain containing 17C | -0.0119728 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0118757 |
| RPL4 | ribosomal protein L4 | -0.0118496 |
