| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fingolimod (hydrochloride)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.235546 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.112864 |
| DTNA | dystrobrevin, alpha | 0.112365 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0933132 |
| MMP12 | matrix metallopeptidase 12 | 0.0731505 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0728429 |
| NUP58 | nucleoporin 58 | 0.0713369 |
| ATP13A3 | ATPase type 13A3 | 0.0657815 |
| YBX3 | Y box binding protein 3 | 0.0640661 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0631977 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0629195 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0593327 |
| SPAG9 | sperm associated antigen 9 | 0.0589008 |
| MSN | moesin | 0.057737 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0546822 |
| CD109 | CD109 molecule | 0.0537805 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0508471 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0507803 |
| RUNX1 | runt-related transcription factor 1 | 0.0493955 |
| RPS6 | ribosomal protein S6 | 0.0487713 |
| RPS2 | ribosomal protein S2 | 0.0476702 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0464543 |
| DST | dystonin | 0.0459342 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0452189 |
| JMJD1C | jumonji domain containing 1C | 0.0442131 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0441324 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0436899 |
| CTSB | cathepsin B | 0.0419844 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0416566 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.041544 |
| HAS2 | hyaluronan synthase 2 | 0.0414962 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0407855 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0402924 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0401491 |
| MALT1 | MALT1 paracaspase | 0.0400424 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0398009 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0396437 |
| NDRG1 | N-myc downstream regulated 1 | 0.0395614 |
| WDR43 | WD repeat domain 43 | 0.0394879 |
| RNF145 | ring finger protein 145 | 0.0389723 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0384617 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0382793 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.037958 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0375016 |
| FRMD6 | FERM domain containing 6 | 0.0363107 |
| QKI | QKI, KH domain containing, RNA binding | 0.0356409 |
| MYO10 | myosin X | 0.0347963 |
| NCKAP1 | NCK-associated protein 1 | 0.0346464 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0340708 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0340229 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0338053 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0337402 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0331225 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0327847 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0327582 |
| TPM4 | tropomyosin 4 | 0.0322114 |
| LIMA1 | LIM domain and actin binding 1 | 0.0319797 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0319587 |
| RBM39 | RNA binding motif protein 39 | 0.0318723 |
| RASA2 | RAS p21 protein activator 2 | 0.031779 |
| CD44 | CD44 molecule (Indian blood group) | 0.031711 |
| CALD1 | caldesmon 1 | 0.0315781 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0313447 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0313358 |
| RLF | rearranged L-myc fusion | 0.0311909 |
| APP | amyloid beta (A4) precursor protein | 0.0311314 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0309241 |
| MED13L | mediator complex subunit 13-like | 0.0308315 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0308103 |
| RTN4 | reticulon 4 | 0.0305886 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0304126 |
| HELZ | helicase with zinc finger | 0.0302163 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0300138 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0298672 |
| SETD5 | SET domain containing 5 | 0.0297283 |
| PARD3 | par-3 family cell polarity regulator | 0.0291351 |
| PGK1 | phosphoglycerate kinase 1 | 0.0290612 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0289456 |
| RND3 | Rho family GTPase 3 | 0.0289433 |
| STC1 | stanniocalcin 1 | 0.0287522 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0286398 |
| CASC3 | cancer susceptibility candidate 3 | 0.0283153 |
| ZNF292 | zinc finger protein 292 | 0.0282457 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0282208 |
| MYO1B | myosin IB | 0.0280859 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0280006 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0279326 |
| CORO1C | coronin, actin binding protein, 1C | 0.0277694 |
| USP3 | ubiquitin specific peptidase 3 | 0.0277183 |
| PUM2 | pumilio RNA-binding family member 2 | 0.027548 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0274369 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0271265 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0260357 |
| CDK17 | cyclin-dependent kinase 17 | 0.0254631 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0249862 |
| KIF5B | kinesin family member 5B | 0.0249478 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0248785 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0245934 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0244508 |
| VCL | vinculin | 0.0244235 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | -0.0934919 |
| EFNA5 | ephrin-A5 | -0.0850131 |
| ASPH | aspartate beta-hydroxylase | -0.0765928 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0729229 |
| RPS27A | ribosomal protein S27a | -0.0709962 |
| RPL23 | ribosomal protein L23 | -0.0673671 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0557531 |
| UBC | ubiquitin C | -0.0508453 |
| FLNA | filamin A, alpha | -0.0444253 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0424909 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.041094 |
| NAV1 | neuron navigator 1 | -0.0400477 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0379962 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0363468 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0354157 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0352776 |
| AEBP2 | AE binding protein 2 | -0.0352412 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0351496 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0348229 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0346452 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0341988 |
| PRKCE | protein kinase C, epsilon | -0.033914 |
| INTS6 | integrator complex subunit 6 | -0.033075 |
| TMSB10 | thymosin beta 10 | -0.0320224 |
| CDH13 | cadherin 13 | -0.0316174 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.031035 |
| GPC6 | glypican 6 | -0.0308531 |
| PRELID2 | PRELI domain containing 2 | -0.0306266 |
| ACTG1 | actin gamma 1 | -0.0296696 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0284148 |
| ZNF804A | zinc finger protein 804A | -0.027957 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0274379 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0270146 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0232987 |
| VIM | vimentin | -0.023103 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0230732 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0226415 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.022584 |
| RPS4X | ribosomal protein S4, X-linked | -0.0223275 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0220405 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0219873 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0219383 |
| ENO1 | enolase 1, (alpha) | -0.0215765 |
| KIAA1549L | KIAA1549-like | -0.0213249 |
| RAD51B | RAD51 paralog B | -0.0211655 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0210719 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0207921 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0205486 |
| RPL9 | ribosomal protein L9 | -0.0203923 |
| RPS17 | ribosomal protein S17 | -0.0201589 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0197357 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0196611 |
| RPL37A | ribosomal protein L37a | -0.019294 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0191974 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0189495 |
| RPLP2 | ribosomal protein, large, P2 | -0.0185515 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0182543 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0182436 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0181234 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0180862 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0180141 |
| SMYD3 | SET and MYND domain containing 3 | -0.017856 |
| PKP4 | plakophilin 4 | -0.0176693 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0172339 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0170938 |
| RPS12 | ribosomal protein S12 | -0.0170446 |
| EXOC4 | exocyst complex component 4 | -0.0170105 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0168428 |
| KIAA1217 | KIAA1217 | -0.0166662 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0166054 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0165626 |
| CTIF | CBP80/20-dependent translation initiation factor | -0.0165401 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0165098 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0164336 |
| RNF213 | ring finger protein 213 | -0.0164129 |
| MYO9A | myosin IXA | -0.016362 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0163566 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0163022 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0162883 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0161819 |
| RPS8 | ribosomal protein S8 | -0.0160863 |
| PCBP2 | poly(rC) binding protein 2 | -0.0160486 |
| NTM | neurotrimin | -0.0158787 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0158704 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0155678 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0153077 |
| EXOC6B | exocyst complex component 6B | -0.0152002 |
| SNX14 | sorting nexin 14 | -0.0151327 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0146483 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0143835 |
| ZNF638 | zinc finger protein 638 | -0.0143495 |
| NBEA | neurobeachin | -0.0142005 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0141941 |
| DENND1A | DENN/MADD domain containing 1A | -0.014154 |
| ATXN1 | ataxin 1 | -0.0141449 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0140205 |
| AMOTL2 | angiomotin like 2 | -0.0140128 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0138869 |
| TBCA | tubulin folding cofactor A | -0.0138067 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0136008 |
