| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fingolimod (hydrochloride) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fingolimod (hydrochloride)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | 0.0422398 |
| SPAG9 | sperm associated antigen 9 | 0.0411182 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0327873 |
| NGLY1 | N-glycanase 1 | 0.0289641 |
| ARRDC3 | arrestin domain containing 3 | 0.0281091 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0276559 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0274184 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0265368 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0265166 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0235978 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0235244 |
| TMEM165 | transmembrane protein 165 | 0.0228335 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0219095 |
| HELZ | helicase with zinc finger | 0.0203581 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0203161 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0201351 |
| RUNX1 | runt-related transcription factor 1 | 0.0197185 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0192406 |
| TPD52 | tumor protein D52 | 0.0191003 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0190464 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.019016 |
| UVRAG | UV radiation resistance associated | 0.0185201 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0184182 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0175867 |
| FNIP1 | folliculin interacting protein 1 | 0.0173916 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0173377 |
| SUCO | SUN domain containing ossification factor | 0.0172101 |
| NDRG1 | N-myc downstream regulated 1 | 0.0167236 |
| OGA | O-GlcNAcase | 0.0163094 |
| PAPOLA | poly(A) polymerase alpha | 0.0158961 |
| RPS2 | ribosomal protein S2 | 0.0158866 |
| NCKAP1 | NCK-associated protein 1 | 0.0158718 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0158304 |
| SRP54 | signal recognition particle 54kDa | 0.0156885 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0156252 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0153101 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0145908 |
| RNF145 | ring finger protein 145 | 0.0145638 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0143991 |
| ATP13A3 | ATPase type 13A3 | 0.014314 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0142866 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0142329 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0141875 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0138408 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0137188 |
| HBP1 | HMG-box transcription factor 1 | 0.0137174 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.013564 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0134951 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0134818 |
| NUP58 | nucleoporin 58 | 0.0134512 |
| SEC24A | SEC24 family member A | 0.0134215 |
| WDR45B | WD repeat domain 45B | 0.0132401 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0131656 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0129906 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.012926 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0127242 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0126631 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0125998 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0125785 |
| PDE8A | phosphodiesterase 8A | 0.012447 |
| NPTN | neuroplastin | 0.0121026 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0120449 |
| ATG14 | autophagy related 14 | 0.0118452 |
| SQSTM1 | sequestosome 1 | 0.011754 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0116812 |
| HYOU1 | hypoxia up-regulated 1 | 0.0116444 |
| TMF1 | TATA element modulatory factor 1 | 0.0115651 |
| TFG | TRK-fused gene | 0.0115392 |
| TOP1 | topoisomerase (DNA) I | 0.0113933 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0111386 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0109041 |
| DTNA | dystrobrevin, alpha | 0.0105291 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0104962 |
| RBM39 | RNA binding motif protein 39 | 0.0104591 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0104457 |
| NDE1 | nudE neurodevelopment protein 1 | 0.0103742 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0100815 |
| ANO6 | anoctamin 6 | 0.010073 |
| ECT2 | epithelial cell transforming 2 | 0.0100706 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0100283 |
| WAC | WW domain containing adaptor with coiled-coil | 0.00992057 |
| SLMAP | sarcolemma associated protein | 0.00982833 |
| MATR3 | matrin 3 | 0.00977322 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.00972169 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.00964176 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.00964 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00957425 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.00954074 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.00944874 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.00940256 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.00939461 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0093585 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.00933185 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0092977 |
| CASC3 | cancer susceptibility candidate 3 | 0.00928918 |
| SETD5 | SET domain containing 5 | 0.00925518 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.00923676 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.00922727 |
| H1-0 | H1.0 linker histone | 0.0091847 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.00915426 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.208024 |
| EGFR | epidermal growth factor receptor | -0.099071 |
| MT2A | metallothionein 2A | -0.0970249 |
| TMSB10 | thymosin beta 10 | -0.0869807 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0621457 |
| TXNRD1 | thioredoxin reductase 1 | -0.0553187 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0457121 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0396912 |
| ASPH | aspartate beta-hydroxylase | -0.0389671 |
| RPL35A | ribosomal protein L35a | -0.0387258 |
| OSMR | oncostatin M receptor | -0.0370295 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0350928 |
| RPLP1 | ribosomal protein, large, P1 | -0.0348871 |
| EFNA5 | ephrin-A5 | -0.0322991 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.031832 |
| S100A10 | S100 calcium binding protein A10 | -0.0316755 |
| EGR1 | early growth response 1 | -0.0313788 |
| ACTG1 | actin gamma 1 | -0.0299171 |
| SEC61G | Sec61 gamma subunit | -0.0295345 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0293896 |
| CST3 | cystatin C | -0.0282243 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0281339 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.026708 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0262661 |
| RNF213 | ring finger protein 213 | -0.0260056 |
| GRAMD1B | GRAM domain containing 1B | -0.0254973 |
| PKM | pyruvate kinase, muscle | -0.0250104 |
| FOXP1 | forkhead box P1 | -0.0238667 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.023746 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0234415 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0230036 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0214815 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0214742 |
| HLA-B | major histocompatibility complex, class I, B | -0.0205658 |
| AREG | amphiregulin | -0.0205487 |
| RPS24 | ribosomal protein S24 | -0.020428 |
| MT1X | metallothionein 1X | -0.020331 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0203073 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.020257 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0199351 |
| RPL34 | ribosomal protein L34 | -0.0194497 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0193213 |
| LDHA | lactate dehydrogenase A | -0.0192731 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0190596 |
| KRT7 | keratin 7, type II | -0.0189078 |
| CCND1 | cyclin D1 | -0.0187122 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0186552 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0182609 |
| RPS25 | ribosomal protein S25 | -0.0181387 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0181013 |
| FTL | ferritin, light polypeptide | -0.018054 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0178376 |
| SMYD3 | SET and MYND domain containing 3 | -0.0178213 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0177225 |
| S100A9 | S100 calcium binding protein A9 | -0.017626 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0176012 |
| STC1 | stanniocalcin 1 | -0.0175276 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0175172 |
| ENO1 | enolase 1, (alpha) | -0.017391 |
| RPL31 | ribosomal protein L31 | -0.0171455 |
| RPL37A | ribosomal protein L37a | -0.0169918 |
| S100A11 | S100 calcium binding protein A11 | -0.0167314 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0166406 |
| B2M | beta-2-microglobulin | -0.0164499 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0160881 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0160513 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0158974 |
| RPL23 | ribosomal protein L23 | -0.0158853 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0156647 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0154691 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0154539 |
| RPS19 | ribosomal protein S19 | -0.0153852 |
| KRT18 | keratin 18, type I | -0.0151215 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0151202 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0151134 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0148643 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0147769 |
| RPLP2 | ribosomal protein, large, P2 | -0.0145891 |
| RAD51B | RAD51 paralog B | -0.0145665 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0145565 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0144416 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0144071 |
| IER3 | immediate early response 3 | -0.01424 |
| BPTF | bromodomain PHD finger transcription factor | -0.0142172 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0140323 |
| RPS8 | ribosomal protein S8 | -0.0139938 |
| VCL | vinculin | -0.013987 |
| KRT8 | keratin 8, type II | -0.013976 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0138914 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0137168 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0136548 |
| RPS29 | ribosomal protein S29 | -0.013459 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0134444 |
| LAMA4 | laminin, alpha 4 | -0.0132437 |
| RPL30 | ribosomal protein L30 | -0.013197 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0131872 |
| RPS3 | ribosomal protein S3 | -0.0131844 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0130733 |
| ANXA2 | annexin A2 | -0.0130436 |
| S100P | S100 calcium binding protein P | -0.0129117 |
